Modelling The Biology And Transmission Of Influenza Virus - Learning From 1918-19 And Other Outbreaks
Funder
National Health and Medical Research Council
Funding Amount
$114,222.00
Summary
In preparing for a future pandemic of influenza, it is important to learn as much as possible from what happened in the past, particularly from the devastating pandemic of 1918-19. This project will collate detailed information about the spread of influenza in past outbreaks and create a publicly accessible data-base. Mathematical methods will be used to analyse historic and contemporary data, so as to provide better understanding of the spread of influenza, and of the likely effects of social a ....In preparing for a future pandemic of influenza, it is important to learn as much as possible from what happened in the past, particularly from the devastating pandemic of 1918-19. This project will collate detailed information about the spread of influenza in past outbreaks and create a publicly accessible data-base. Mathematical methods will be used to analyse historic and contemporary data, so as to provide better understanding of the spread of influenza, and of the likely effects of social and medical measures for its control. An important theme of the project is to consolidate our knowledge about how past exposure to non-pandemic influenza could provide short-lived protection against any new pandemic, and to explore the implications of this for prevention today. Another theme is to explore the severity of influenza during pandemics, and to identify social and medical factors that might reduce the dose of virus transmitted, or otherwise reduce the severity of infection. The insights from the modeling will also help to identify gaps in knowledge and understanding about the basic biology of influenza, stimulate new research to fill those gaps, and thus offer the prospect of more effective vaccines and treatments for the future control of influenza.Read moreRead less
Deadly Liver Mob: Engaging Aboriginal People In Viral Hepatitis, HIV And Sexual Health Services
Funder
National Health and Medical Research Council
Funding Amount
$848,441.00
Summary
Rates of blood-borne viruses and sexually transmissible infections are high among the Aboriginal and Torres Strait Islander population. A local initiative in western Sydney has trialed a new approach to engagement and care of Aboriginal people. We will implement this approach in services across NSW and evaluate its effectiveness as a sustainable and acceptable model for engaging Aboriginal people in care and develop an implementation plan for future roll-out to other services.
Arbovirus Activation And Modulation Of NLRP3 Inflammasome
Funder
National Health and Medical Research Council
Funding Amount
$779,720.00
Summary
This project aims to establish how mosquito borne viruses such as Ross River and dengue viruses interacts with the human host to cause disease, including how the virus evades the host’s immune response to persist and cause disease for prolonged periods. Knowing how differences in the virus and the host’s immune system interplay to cause asymptomatic to severely disabling disease will assist in devising new treatments and prevention programs to lessen the impact of these diseases in Australia.
Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hard ....Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hardware, software and communication systems to dynamically generate decision tools for safe and efficient power system operating conditions. These systems will also generate alarms if any risky operational situations arise.Read moreRead less
Performance analysis of the Unified Power Flow Controller based on multi-bridge converter. The objective of this research is to conceive a new configuration of UPFC without series injection transformers, based on two-level full-bridge modules. The conceived system can be utilized for the power systems to control the power flow through the transmission line.
The benefit is in reducing restrictions on electricity transfer links.
The project will develop a laboratory version of the novel UPFC de ....Performance analysis of the Unified Power Flow Controller based on multi-bridge converter. The objective of this research is to conceive a new configuration of UPFC without series injection transformers, based on two-level full-bridge modules. The conceived system can be utilized for the power systems to control the power flow through the transmission line.
The benefit is in reducing restrictions on electricity transfer links.
The project will develop a laboratory version of the novel UPFC demonstrating the hardware and control requirements for this form of UPFC which could reduce the costs of this corrective solution up to 30% below existing solutions.
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EMERGENCY CONTROL FOR POWER SYSTEM SEPARATION. In 2003 we saw major blackouts of power systems for US/Canada, Italy and London leading to billions of dollars of lost production and major impacts on many peoples lives. One aspect contributing to some of these is the control of system dynamic response and the targeted use of emergency controls such as load and generator shedding. This project is contributing to the development of an integrated control response such that appropriate levels of emerg ....EMERGENCY CONTROL FOR POWER SYSTEM SEPARATION. In 2003 we saw major blackouts of power systems for US/Canada, Italy and London leading to billions of dollars of lost production and major impacts on many peoples lives. One aspect contributing to some of these is the control of system dynamic response and the targeted use of emergency controls such as load and generator shedding. This project is contributing to the development of an integrated control response such that appropriate levels of emergency controls are determined and the probability of cascading blackouts reduced through automated systems. Read moreRead less
Advanced Planning Tools for the Prevention of System-wide Blackouts of Large Power Systems. In 2003 there had been major power blackouts in US/Canada, Italy and in Scandinavia leading to billions of dollars of lost production and had raised concern about national security. Prevention of blackout should be one of the highest priorities of the electricity industry. National security for any critical infrastructure of any country is more vulnerable for a prolonged blackout. This project will provid ....Advanced Planning Tools for the Prevention of System-wide Blackouts of Large Power Systems. In 2003 there had been major power blackouts in US/Canada, Italy and in Scandinavia leading to billions of dollars of lost production and had raised concern about national security. Prevention of blackout should be one of the highest priorities of the electricity industry. National security for any critical infrastructure of any country is more vulnerable for a prolonged blackout. This project will provide comprehensive planning tools to prevent blackouts in the Australian National Electricity grid. Any benefit to electricity industry will finally result in further benefits to the national economy and security as a whole.
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Investigation of Demand Diversity and Appropriate New Generation Entry into Electricity Market Simulation Tools. The power industry is currently facing a great challenge in providing
better market operation and management following recent devastating blackouts in North America, UK and Italy. This project aims at investigating major mechanisms of market simulation techniques including impacts from load diversity and approaches to defining appropriate new generation entry into the market. From th ....Investigation of Demand Diversity and Appropriate New Generation Entry into Electricity Market Simulation Tools. The power industry is currently facing a great challenge in providing
better market operation and management following recent devastating blackouts in North America, UK and Italy. This project aims at investigating major mechanisms of market simulation techniques including impacts from load diversity and approaches to defining appropriate new generation entry into the market. From the outcome of this project the National Electricity Market will be able to manage the uncertainties of load diversity (one of the most common blackout causes), and efficiently minimise risk associated with decisions on new generation entry to enhance electricity supply infrastructure.
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POWER DELIVERY IN A DEREGULATED ENVIRONMENT. The recent deregulation of the power industry has opened up new technical challenges that must be addressed in order to ensure fair and equitable market operation. Significant among these is the availability of alternative routes for the delivery of power, between and across different ownerships. In this scenario, a major challenge is to determine the minimum cost contractual arrangement for the delivery of required power. To achieve this, new techniq ....POWER DELIVERY IN A DEREGULATED ENVIRONMENT. The recent deregulation of the power industry has opened up new technical challenges that must be addressed in order to ensure fair and equitable market operation. Significant among these is the availability of alternative routes for the delivery of power, between and across different ownerships. In this scenario, a major challenge is to determine the minimum cost contractual arrangement for the delivery of required power. To achieve this, new techniques for the analysis of power systems are required. This proposal aims to provide solutions to these analysis problems and hence to provide software to assist with market operation.Read moreRead less