Modelling The Biology And Transmission Of Influenza Virus - Learning From 1918-19 And Other Outbreaks
Funder
National Health and Medical Research Council
Funding Amount
$114,222.00
Summary
In preparing for a future pandemic of influenza, it is important to learn as much as possible from what happened in the past, particularly from the devastating pandemic of 1918-19. This project will collate detailed information about the spread of influenza in past outbreaks and create a publicly accessible data-base. Mathematical methods will be used to analyse historic and contemporary data, so as to provide better understanding of the spread of influenza, and of the likely effects of social a ....In preparing for a future pandemic of influenza, it is important to learn as much as possible from what happened in the past, particularly from the devastating pandemic of 1918-19. This project will collate detailed information about the spread of influenza in past outbreaks and create a publicly accessible data-base. Mathematical methods will be used to analyse historic and contemporary data, so as to provide better understanding of the spread of influenza, and of the likely effects of social and medical measures for its control. An important theme of the project is to consolidate our knowledge about how past exposure to non-pandemic influenza could provide short-lived protection against any new pandemic, and to explore the implications of this for prevention today. Another theme is to explore the severity of influenza during pandemics, and to identify social and medical factors that might reduce the dose of virus transmitted, or otherwise reduce the severity of infection. The insights from the modeling will also help to identify gaps in knowledge and understanding about the basic biology of influenza, stimulate new research to fill those gaps, and thus offer the prospect of more effective vaccines and treatments for the future control of influenza.Read moreRead less
Deadly Liver Mob: Engaging Aboriginal People In Viral Hepatitis, HIV And Sexual Health Services
Funder
National Health and Medical Research Council
Funding Amount
$848,441.00
Summary
Rates of blood-borne viruses and sexually transmissible infections are high among the Aboriginal and Torres Strait Islander population. A local initiative in western Sydney has trialed a new approach to engagement and care of Aboriginal people. We will implement this approach in services across NSW and evaluate its effectiveness as a sustainable and acceptable model for engaging Aboriginal people in care and develop an implementation plan for future roll-out to other services.
Arbovirus Activation And Modulation Of NLRP3 Inflammasome
Funder
National Health and Medical Research Council
Funding Amount
$779,720.00
Summary
This project aims to establish how mosquito borne viruses such as Ross River and dengue viruses interacts with the human host to cause disease, including how the virus evades the host’s immune response to persist and cause disease for prolonged periods. Knowing how differences in the virus and the host’s immune system interplay to cause asymptomatic to severely disabling disease will assist in devising new treatments and prevention programs to lessen the impact of these diseases in Australia.
Boolean plasmonics: the design of nano-optical logic gates. The success of this project will see the development of an all-optical nano-scale logic gate. Such a device will drastically improve communications and information technology. Standard lithographic techniques will be used ensuring reproducibility and mass production, placing Australia at the forefront of the photonic market.
A new photoelectrochemical system for solar hydrogen and electricity. This project aims to develop a new integrated photoelectrochemical (PEC) system for converting solar energy into hydrogen and electricity simultaneously. The key concept is to design innovative advanced materials which will be integrated into PEC devices with capacitor function for both solar fuel production and electricity storage. This project expects to generate new knowledge in understanding the fundamental mechanism of de ....A new photoelectrochemical system for solar hydrogen and electricity. This project aims to develop a new integrated photoelectrochemical (PEC) system for converting solar energy into hydrogen and electricity simultaneously. The key concept is to design innovative advanced materials which will be integrated into PEC devices with capacitor function for both solar fuel production and electricity storage. This project expects to generate new knowledge in understanding the fundamental mechanism of developing functional materials for more efficient solar energy conversion and storage. Expected outcomes include prototypes of the next generation advanced materials and technologies for sustainable energy utilisation systems for converting solar energy into hydrogen and electricity.Read moreRead less
Perovskite Materials: Exploring properties beyond solar cells. This project aims to explore functionalities of metal halide perovskite materials for sustainable solar energy conversion and storage, beyond the heavily studied perovskite solar cell application. The project intends to design toxic lead free/less perovskite materials for an integrated photoelectrochemical hydrogen production and solar rechargeable battery system. It will study the relations between material synthesis conditions, dev ....Perovskite Materials: Exploring properties beyond solar cells. This project aims to explore functionalities of metal halide perovskite materials for sustainable solar energy conversion and storage, beyond the heavily studied perovskite solar cell application. The project intends to design toxic lead free/less perovskite materials for an integrated photoelectrochemical hydrogen production and solar rechargeable battery system. It will study the relations between material synthesis conditions, device structure and performance of the photoelectrochemical system. Expected outcomes are low cost and more efficient solar-to-hydrogen conversion and solar energy storage devices, important for sustainable use of intermittent solar energy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100003
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin ....3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin modern nanoelectronics for innovative energy, nano-optical and quantum device applications. This unique equipment will facilitate breakthrough discoveries in nanomaterials, and foster collaborations amongst Australian researchers to accelerate industry in advanced nanodevice technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100749
Funder
Australian Research Council
Funding Amount
$368,446.00
Summary
Designing solar rechargeable batteries for efficient solar energy storage. This project aims to develop a new prototype of solar rechargeable battery for the direct storage of solar energy. Specifically, the research will integrate newly designed solar-driven photo-electrochemical energy conversion process and bi-functional photo-electrodes into a lithium-sulphur battery to achieve high energy storage efficiency. Expected outcomes include high-performance solar rechargeable batteries and new kno ....Designing solar rechargeable batteries for efficient solar energy storage. This project aims to develop a new prototype of solar rechargeable battery for the direct storage of solar energy. Specifically, the research will integrate newly designed solar-driven photo-electrochemical energy conversion process and bi-functional photo-electrodes into a lithium-sulphur battery to achieve high energy storage efficiency. Expected outcomes include high-performance solar rechargeable batteries and new knowledge generated from the integration of interdisciplinary research in energy storage, photo-electrochemistry and nanotechnology. Further advances in material science and solar energy storage technologies will assist in addressing the global energy shortage and mitigating environmental pollution.Read moreRead less
Patchy colloidosomes at interfaces: correlation of particle surface heterogeneity, wettability, and chemical activity at the nanoscale. The surfaces of natural mineral particles are made up of spots with such different chemical and physical properties. The complexity makes it hard to predict their behaviour. This project will provide insights into how the 'patchy' nature of particle surfaces affects their behaviour in processes such as flotation separation and bio-fuel production.
Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-as ....Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-assemble into long thermostable fibrils that support cell growth and development. The project’s goal is now to create cost-effective, non-toxic, conducting peptide fibrils that can be used in water or physiological environments for bioelectronics applications.Read moreRead less