Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directiona ....Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directionality changes during accommodation (focusing). The expected outcome is improved understanding of retinal stretching changes during focusing. The benefit is that the project will lead to advancements in retinal imaging.Read moreRead less
Removing the blinkers: a wider study of the human eye. Peripheral aberrations, wide-field retinal imaging and optical parameters. This project will study peripheral (side vision) optics of the human eye and its role in the limits of visual performance. This will improve ocular measurements and contribute towards improved diagnosis and treatment of ocular diseases and short-sightedness.
Advanced methods for intraocular imaging. The ability to image the retina of the human eye at high resolution is fundamental to improving understanding of ocular physiology, ocular optics and disease diagnosis. This project applies the relatively new application of active optics to vision science. This project will investigate the advantages of using new beam shaping techniques for characterising the optics of the eye, improving retinal imagery and improving fixation stability. This project will ....Advanced methods for intraocular imaging. The ability to image the retina of the human eye at high resolution is fundamental to improving understanding of ocular physiology, ocular optics and disease diagnosis. This project applies the relatively new application of active optics to vision science. This project will investigate the advantages of using new beam shaping techniques for characterising the optics of the eye, improving retinal imagery and improving fixation stability. This project will achieve three-dimensional holography of human eyes and develop holography plates for correcting the aberrations of eyes. Expected outcomes are not-before experienced resolution images of the retina and better understanding of the optical characteristics of the refractive surfaces and media in the eye.Read moreRead less
Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to ....Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to investigate a broad range of cognitive and communication functions. Benefits will include potential technologies and algorithms to assist listening (in devices such as hearing aids), language development and reading.Read moreRead less
Understanding lens aging: the molecular basis of presbyopia. Ageing has major consequences in the deterioration of vision, notably, the inability to focus on near objects. The understanding gained through this study of age-related lens changes may allow us to prescribe drugs or diets that alter lens properties and thus delay the need for glasses. This would have great benefits not just in decreased inconvenience of users, but also in cost to the middle-aged and elderly. In addition, data will b ....Understanding lens aging: the molecular basis of presbyopia. Ageing has major consequences in the deterioration of vision, notably, the inability to focus on near objects. The understanding gained through this study of age-related lens changes may allow us to prescribe drugs or diets that alter lens properties and thus delay the need for glasses. This would have great benefits not just in decreased inconvenience of users, but also in cost to the middle-aged and elderly. In addition, data will be used to underpin the development of a flexible intraocular lens (IOL). Hard IOLs are routinely inserted into human eyes following cataract surgery. In the future, flexible IOLs based on the properties of young lenses will be used, rather than reading glasses. This new industry could be based in Australia.Read moreRead less
Identifying the basis for perceptual stability and perceptual omission during saccadic eye movements. The ability to explore the world via eye movements is an important feature of visual capabilities. This project will establish how the brain maintains the perception of a stable and stationary world despite the several eye movements made each second. This knowledge will fill a conspicuous gap in the understanding of the human visual system.
Functional Electronic Stimulation of Muscles - Development of a Model for Sensory Feedback to Amputees and Vision for the Blind. Electrical stimulation of nerve fibres is an emerging physiological technique with great promise towards rehabilitation. The field lacks techniques for detailed, focal application of stimuli to recruit specific fibres for fine muscle control or conveying useful neurosensory information. The investigator has developed microtechnology for delivering stimuli to 100 sites, ....Functional Electronic Stimulation of Muscles - Development of a Model for Sensory Feedback to Amputees and Vision for the Blind. Electrical stimulation of nerve fibres is an emerging physiological technique with great promise towards rehabilitation. The field lacks techniques for detailed, focal application of stimuli to recruit specific fibres for fine muscle control or conveying useful neurosensory information. The investigator has developed microtechnology for delivering stimuli to 100 sites, conceivably facilitating recruitment of specific fibres within a given bundle. Effects of muscle stimulation are readily measured and shall be used to model and refine techniques for generic high-resolution fibre recruitment. Benefits include, improved muscle control in functional electrical stimulation, sensory perception for amputees and patterned vision from optic nerve stimulation.Read moreRead less
Large-scale Parallelization of Neural Stimulation in a Visual Prosthesis. Over time, engineers have been able to treat a large number of disorders through new technologies. For example, the deaf can now hear again through cochlear implants. Similar efforts to provide vision to the blind, however, have met with difficulties owing to the high quantities of sites that must be stimulated to provide 'useful' vision. This study addresses the important issues relating to the delivery of large quantitie ....Large-scale Parallelization of Neural Stimulation in a Visual Prosthesis. Over time, engineers have been able to treat a large number of disorders through new technologies. For example, the deaf can now hear again through cochlear implants. Similar efforts to provide vision to the blind, however, have met with difficulties owing to the high quantities of sites that must be stimulated to provide 'useful' vision. This study addresses the important issues relating to the delivery of large quantities of electrical stimulations to surviving nerves in the eyes of blind patients in an effort to devise a beneficial visual prosthesis or 'bionic eye'. The outcomes of this study could substantially enhance Australia's already prominent reputation in neurostimulation and provide much needed treatments to vision disorders.Read moreRead less
An investigation of respiration in stuttering. Australia leads the world in stuttering research, and this project will maintain that profile. The research aims to establish if breathing has a causal role in stuttering. The new knowledge produced will support or weaken current theories of the cause of stuttering and will contribute to understanding the nature of the disorder. In particular, it will be applied to develop more effective and efficient treatments for chronic stuttering.
Establishing the relationship between anxiety and stuttering. The present project will establish basic knowledge about the disorder of stuttering, which will contribute to offsetting the personal and community costs of the disorder by guiding empirical investigations into its nature and the development of future treatments. Further benefits at the population level will occur by provision to the public of basic information about the disorder assembled from this project. By conveying information f ....Establishing the relationship between anxiety and stuttering. The present project will establish basic knowledge about the disorder of stuttering, which will contribute to offsetting the personal and community costs of the disorder by guiding empirical investigations into its nature and the development of future treatments. Further benefits at the population level will occur by provision to the public of basic information about the disorder assembled from this project. By conveying information from the present project to clinicians who treat stuttering patients, the project will benefit Australians who stutter.Read moreRead less