Humanisation And Pre-clinical Validation Of A Therapeutic Anti-cancer Antibody
Funder
National Health and Medical Research Council
Funding Amount
$699,136.00
Summary
This grant will develop a novel antibody against a protease expressed on cancer cells. Preclinical studies, and antibody humanisation, will be performed. This project will also provide vital information on optimal therapeutic approaches with the antibody that can be ultimately taken into human trials.
ADAM Metalloprotease Inhibition For Treatment Of Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$770,925.00
Summary
Colorectal cancer (CRC) causes over 4000 deaths/year, typically from developing drug resistance and spreading to other organs (metastasis). These processes involve tumour cells called cancer stem cells (CSCs), which rely on specific cell surface proteins for survival and function. We are developing antibodies against one of these type of proteins, to test in mouse models of CRC. These already show promise in targeting CSCs and inhibiting drug-resistance and metastasis in mice.
Exploring Botanic Gardens Herbarium's value, via Environmental Aesthetics. . The project aims to aesthetically redefine engagement with the plant collection at Royal Botanic Gardens Herbarium (RBG) Sydney and to communicate its artistic, cultural and heritage value to the public through a Public Program of creative arts case studies. It's expected that new insights will arise from an environmental art methodology utilising the digitisation of the Herbarium specimens, so that audiences can intera ....Exploring Botanic Gardens Herbarium's value, via Environmental Aesthetics. . The project aims to aesthetically redefine engagement with the plant collection at Royal Botanic Gardens Herbarium (RBG) Sydney and to communicate its artistic, cultural and heritage value to the public through a Public Program of creative arts case studies. It's expected that new insights will arise from an environmental art methodology utilising the digitisation of the Herbarium specimens, so that audiences can interactively experience the plant archive through narratives that activate plants as underpinning ecosystems. Benefits to partners RBG, Bundanon Trust and Open Humanities Press will include the digital expansion of audience engagement with the Herbarium at RBG and Mt Annan and communication of collection’s significance.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775489
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the developm ....Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the development of national identity through the diversity and richness of Australia's visual cultures. Read moreRead less
A new theory of Aboriginal art. The paradigms developed by scholars have a huge impact on the value of art. After the Australian artworld repositioned Aboriginal art from the frame of 'primitive art' to that of contemporary art, the price of and market for Aboriginal art increased enormously. However, Aboriginal art failed to penetrate the international contemporary artworld because the paradigms of contemporary art within which it was framed were outmoded. Through examining the production of Ab ....A new theory of Aboriginal art. The paradigms developed by scholars have a huge impact on the value of art. After the Australian artworld repositioned Aboriginal art from the frame of 'primitive art' to that of contemporary art, the price of and market for Aboriginal art increased enormously. However, Aboriginal art failed to penetrate the international contemporary artworld because the paradigms of contemporary art within which it was framed were outmoded. Through examining the production of Aboriginal art from the perspectives of its producers and recent globalised contemporary art practices, this project aims to develop a new theory of Aboriginal art that is more aligned with the thinking of current curators who set the agenda at the upper end of the market.Read moreRead less
Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of t ....Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of the media industries. This is designed to deliver new knowledge of the skills and subject matter that sustained filmmaking, communication and education in Australia during a time when conventional scholarship assumes there was almost no significant filmmaking.Read moreRead less
A history of press photography in Australia. Press photography has long influenced how Australians have understood themselves and their world. In collaboration with the National Library of Australia and the Walkley Foundation, the project explores the evolving role of photographs in breaking news, and historical shifts in photographic technologies, media practices and ethics.
The reformulation of landscape as a user-generated interactive aesthetic. This project seeks to provide Australia with an opportunity to advance its understanding of landscape and climate change by building the world's first networked landscape visualisation system.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453517
Funder
Australian Research Council
Funding Amount
$205,800.00
Summary
240 x 360 degree digital video camera for interactive immersive visualization research applications. This proposal involves the acquisition of a high resolution 240x360 degree digital video camera and three post-production facilities. The equipment will allow, for the first time, the development of truly global interactive and immersive imaging and projection systems possessing digital capture at 25FPS on a scale to match conventional cinematic techniques. It will provide Australia's leading gro ....240 x 360 degree digital video camera for interactive immersive visualization research applications. This proposal involves the acquisition of a high resolution 240x360 degree digital video camera and three post-production facilities. The equipment will allow, for the first time, the development of truly global interactive and immersive imaging and projection systems possessing digital capture at 25FPS on a scale to match conventional cinematic techniques. It will provide Australia's leading group of interactive cinema and new media researchers with facilities to employ globally immersive cinematic formats in the research and development of interactive narrative systems, and will allow benefits of these new systems to be realised by the cultural sector and entertainment industry.Read moreRead less
Graphic Encounters: Colonial Prints and the Inscription of Aboriginality. This project plans to collate the archive of prints depicting Indigenous Australians, from national and international collections, to ask how people's place in this newly encroached territory was inscribed by colonial prints. Before the 1890s, prints (engravings, etchings and lithographs) were the principal means of reproducing images. Prints disseminated imagery of Indigenous people and determined how they were 'put in th ....Graphic Encounters: Colonial Prints and the Inscription of Aboriginality. This project plans to collate the archive of prints depicting Indigenous Australians, from national and international collections, to ask how people's place in this newly encroached territory was inscribed by colonial prints. Before the 1890s, prints (engravings, etchings and lithographs) were the principal means of reproducing images. Prints disseminated imagery of Indigenous people and determined how they were 'put in the picture' of settlement. Our colonial-era cultural heritage includes many prints (engravings, etchings, lithographs, etcetera) of Aborigines, yet they have been overlooked and the story of their production, dissemination and consumption is untold. This project aims to collate and trace this visual archive of Indigenous Australians and present its imagery to all Australians, including descendants, in an exhibition and conference, catalogue, monograph and online database.Read moreRead less