Forensic platform technologies for roadside and workplace testing based on nanostructured silicon chips. Roadside drug testing has recently been incorporated into government legislation throughout Australia and abroad. The objective of this project is to develop advanced analysis technologies for implementing effective roadside and workplace testing. The availability of these technologies will increase the safety of Australian drivers and workers.
Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk ass ....Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk assessment. This is intended to be achieved by developing and validating high-throughput in vitro toxicity screening platforms for manufactured nanoparticles. The approach is based on advanced lab-on-a-chip microfluidic technologies. The predictive power of the platform will be refined and optimised via ex-vivo and in-vivo models.Read moreRead less
Electrochemical sensors as early alert screening tools for water quality assessment. This project will impact on water safety assessment and provide better management tools for water pollutant control. It will address a real need to develop on-line detection technologies for application in the water industry and will demonstrate the potential broad applicability of this technology to a wide range of analytes of concern.
Building bio-inspired smart nanochannels for virus detection. This project aims to harness high-precision silicon nanofabrication methods to create the next generation of bio-inspired viral biosensors. The new technology would enable prompt, cost-efficient, and accurate detection of virus contamination of our water and food supplies. The project plans to fabricate arrays of parallel double-layered nanochannels in silicon via templated etching, with surface functionalisation to display receptors. ....Building bio-inspired smart nanochannels for virus detection. This project aims to harness high-precision silicon nanofabrication methods to create the next generation of bio-inspired viral biosensors. The new technology would enable prompt, cost-efficient, and accurate detection of virus contamination of our water and food supplies. The project plans to fabricate arrays of parallel double-layered nanochannels in silicon via templated etching, with surface functionalisation to display receptors. These nanochannels are designed to act as size-selective filters for electrochemical and electrochemiluminescence sensing. The project plans to explore innovative signal amplification and multiplexing capabilities for ultrasensitive detection of norovirus and bacteriophages.Read moreRead less