A group of bacteria called Neisseria cause human-specific infections. To initiate infection, the bacteria must produce a hair-like surface structure, the pilus. The pilus consists mainly of a protein called pilin, and we now understand how pilin production is controlled. However 20 other genes are also involved in pilus production. This project aims to understand how these other genes are controlled and coordinated to assemble this structure that is central to the ability to cause disease.
What Determines Patients' Adherence To Treatment In Cardiovascular Disease Prevention? A Process Evaluation Of The Kanyini_GAP Trial
Funder
National Health and Medical Research Council
Funding Amount
$254,251.00
Summary
Cardiovascular disease is the leading cause of death and disability in Australia with a disproportionate burden borne by Aboriginal populations. Despite the existence of proven treatments, adherence to therapy is a major problem. Based on the use of well-established survey methods involving patients, GPs and pharmacists the study seeks to better understand the reasons for non-adherence and why different strategies to address this may or may not be effective.