Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlyin ....Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlying biological and biomedical processes, bringing sustainable discovery of new relationships and variations within the data. The project aims to support new approaches to medical diagnosis and treatment, and offer crucial lessons to address the broader challenge of understanding large, complex data sets.Read moreRead less
Understanding the koala microbiome: unlocking the secrets of koala health and dietary specialisation, and successful husbandry and translocation. This project aims to discover how the composition and function of koala gastrointestinal microbial communities differ in space and time in response to the varying nutritional quality and chemical composition of koala diets. Using detailed chemical analysis, cutting edge metagenomic and bioinformatic pipelines and powerful approaches to study enzyme fun ....Understanding the koala microbiome: unlocking the secrets of koala health and dietary specialisation, and successful husbandry and translocation. This project aims to discover how the composition and function of koala gastrointestinal microbial communities differ in space and time in response to the varying nutritional quality and chemical composition of koala diets. Using detailed chemical analysis, cutting edge metagenomic and bioinformatic pipelines and powerful approaches to study enzyme functions in the koala’s gut, the investigators aims to reveal the role of microbes in detoxification of plant toxins and degradation of recalcitrant fibre fractions. The outcomes aim to facilitate the use of faecal transplants to improve digestive function for translocated and rehabilitated koalas, enhancing options for koala management and conservation.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100181
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Strengthening merit-based access and support at the new National Computing Infrastructure petascale supercomputing facility. World-leading high-performance computing is fundamental to Australia's international research success. This facility will provide access to the new National Computational Infrastructure facility by world-leading researchers from six research universities, and sustain ground-breaking work in an increasingly competitive environment.
Social and geographical location and its impact on mathematics teaching and learning. Too many students from poor urban backgrounds or from rural communities are at risk of underperforming in school mathematics. This project identifies the critical factors that contribute to this failure and seeks to develop improved practices to enable greater access to school mathematics.
Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the h ....Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the health system. The data collected in this project will assist in developing health services to meet these needs.Read moreRead less
Co-designing a Food Sovereignty Model with Indigenous Communities. Food sovereignty asserts the rights of people and communities to healthy and culturally appropriate foods through determination of their own food and agriculture systems. With food insecurity higher among Indigenous households; a food sovereignty approach offers the potential for sustainable long-term solutions that maintain human dignity and reinvigorate knowledge systems. Drawing on national and international perspectives and u ....Co-designing a Food Sovereignty Model with Indigenous Communities. Food sovereignty asserts the rights of people and communities to healthy and culturally appropriate foods through determination of their own food and agriculture systems. With food insecurity higher among Indigenous households; a food sovereignty approach offers the potential for sustainable long-term solutions that maintain human dignity and reinvigorate knowledge systems. Drawing on national and international perspectives and using Indigenous research methodologies, this project aims to co-design a food sovereignty model that will enable Indigenous communities to effectively address food insecurity according to their local contexts. Both the process and solutions will contribute to improvements in physical, mental and social wellbeing.Read moreRead less
Reconnecting Warlpiri communities with cultural heritage materials. The projects aims to reconnect Warlpiri communities with past documentation and recordings of their cultural heritage. Centred in Yuendumu, the project expects to unpack the significance of past documentation of cultural heritage for present day Warlpiri people who live in vastly different social worlds from their forebears. Through collaborations with Warlpiri families, and Partner Organisation, Pintupi Anmatyerr Warlpiri (PAW) ....Reconnecting Warlpiri communities with cultural heritage materials. The projects aims to reconnect Warlpiri communities with past documentation and recordings of their cultural heritage. Centred in Yuendumu, the project expects to unpack the significance of past documentation of cultural heritage for present day Warlpiri people who live in vastly different social worlds from their forebears. Through collaborations with Warlpiri families, and Partner Organisation, Pintupi Anmatyerr Warlpiri (PAW) Media and Communications, the project will see the set up of activities to engage with these materials and the production of resources for use by future generations.Read moreRead less
The digitisation of school health and physical education. While there is growing enthusiasm for using digital technology in school health and physical education (HPE), this is happening in the absence of systematic empirical research. This project aims to describe the forms digital HPE is taking, analyse the commercial and ideological forces shaping it, and discuss its impacts. It aims to provide educational stakeholders with a knowledge base on which to anchor debate, policy and further researc ....The digitisation of school health and physical education. While there is growing enthusiasm for using digital technology in school health and physical education (HPE), this is happening in the absence of systematic empirical research. This project aims to describe the forms digital HPE is taking, analyse the commercial and ideological forces shaping it, and discuss its impacts. It aims to provide educational stakeholders with a knowledge base on which to anchor debate, policy and further research concerning the complex ethical and philosophical issues raised by the digitisation of HPE. As the first HPE research grounded in theories of digital culture, the project also aims to challenge the intellectual foundations of HPE teacher training as well as widely held views about the public health role of schools.Read moreRead less
A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship betwee ....A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship between in-prison and post-prison vocational education and employment programs, employment and recidivism. It aims to identify effective elements, strategies, program and policy directions in offender training and employment. This is a unique partnership amongst key academics in the field, peak national bodies, correctional and employment organisations.Read moreRead less