Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
A Genome-wide Association Scan To Identify Genetic Risk Factors For Sight Threatening Diabetic Retinopathy
Funder
National Health and Medical Research Council
Funding Amount
$982,203.00
Summary
Diabetic eye disease is an important complication of diabetes that can lead to blindness. Very little is known about how diabetes causes eye disease, but genetics is known to play a role. We aim to identify genes that contribute to eye disease in diabetes patients. We will compare genes between patients with diabetes with and without severe diabetic eye disease using cutting edge genomic technology. We hope to be able to better predict risk of blindness and to move towards novel treatments.
Computational Intelligence Methods for Financial Applications. Complex financial problems can be better addressed with software that can learn from available data and adapt to environmental changes. It is therefore essential to develop technologies that enable prediction and optimisation in constrained and dynamic environments. There are currently some limitations in existing business decision support systems despite their ubiquity providing an opportunity for Australia to be at the forefront as ....Computational Intelligence Methods for Financial Applications. Complex financial problems can be better addressed with software that can learn from available data and adapt to environmental changes. It is therefore essential to develop technologies that enable prediction and optimisation in constrained and dynamic environments. There are currently some limitations in existing business decision support systems despite their ubiquity providing an opportunity for Australia to be at the forefront as new standards in the field are developed. Furthermore, the fund management industry (particularly superannuation) is significant to the Australian economy and development of this technology has the potential to enhance its performance and reputation.Read moreRead less
The Next Step in Intelligent Decision-Support Systems (IDSS): Systems that Learn and Adapt. This project will benefit Australia's scientific knowledge and technology base in the areas of evolutionary computation, business intelligence, and decision management. The outcomes will advance Australian companies and organisations, as many common yet complex business problems can be better addressed with systems that automatically learn and adapt to environmental changes. Such complex business problems ....The Next Step in Intelligent Decision-Support Systems (IDSS): Systems that Learn and Adapt. This project will benefit Australia's scientific knowledge and technology base in the areas of evolutionary computation, business intelligence, and decision management. The outcomes will advance Australian companies and organisations, as many common yet complex business problems can be better addressed with systems that automatically learn and adapt to environmental changes. Such complex business problems include dynamic scheduling (in the manufacturing sector), resource allocation optimisation (in the defence, mining, and agriculture sectors), and network design optimisation (in the telecommunications and energy sectors).Read moreRead less
Autocalibration without decimation. The insertion of computer generated characters into real footage, the removal of objects from video, and the recovery of 3-dimensional architectural or topographic models from photographs are amongst a growing number of processes used in industry which require highly accurate camera calibration. Autocalibration is thus a prerequisite for these and many other emerging image-based technologies. By developing expertise in this area, and particularly by enabling ....Autocalibration without decimation. The insertion of computer generated characters into real footage, the removal of objects from video, and the recovery of 3-dimensional architectural or topographic models from photographs are amongst a growing number of processes used in industry which require highly accurate camera calibration. Autocalibration is thus a prerequisite for these and many other emerging image-based technologies. By developing expertise in this area, and particularly by enabling more flexible and efficient means of autocalibration, we expect to provide Australian industry with a valuable improvement in the state of the art and a competitive edge in a number of important application areas.Read moreRead less
Combined shape and appearance descriptors for visual object recognition. The quantity of video generated each year is expanding rapidly. This increasing volume of visual information means that it is more likely that any particular event will be recorded, but that the footage will be harder to find. This applies to a collection of home videos as much as to television and movie footage. The object-recognition method to be developed has the potential to alleviate this situation, in which vast amou ....Combined shape and appearance descriptors for visual object recognition. The quantity of video generated each year is expanding rapidly. This increasing volume of visual information means that it is more likely that any particular event will be recorded, but that the footage will be harder to find. This applies to a collection of home videos as much as to television and movie footage. The object-recognition method to be developed has the potential to alleviate this situation, in which vast amounts of video data are available but have little value. Such an outcome would be a boon for Australian industry and offer a valuable export opportunity.Read moreRead less
Multi-objective parameter estimation techniques for computer vision. This project will benefit Australia's scientific knowledge and technology base in the area of computer vision. By contributing improved methods for parameter estimation applicable to a wide variety of technical problems, the project will aid the generation of improved software products in a wide variety of domains. Examples include: augmented reality systems, with which virtual reality artifacts may be immersed within real vid ....Multi-objective parameter estimation techniques for computer vision. This project will benefit Australia's scientific knowledge and technology base in the area of computer vision. By contributing improved methods for parameter estimation applicable to a wide variety of technical problems, the project will aid the generation of improved software products in a wide variety of domains. Examples include: augmented reality systems, with which virtual reality artifacts may be immersed within real video; 3D from 2D systems, with which 3D object structure may be computed from image streams; and visual robotic systems, with which the pose of viewed objects may be determined.Read moreRead less
Automated acquisition of surveillance-camera network topology. The development of an automated system for acquisition of camera network topology is a crucial prerequisite to obtaining intelligent surveillance systems operating at the network level. Such systems will contribute improved methods for safeguarding Australia from terrorism and crime by facilitating the tracking of suspicious individuals and vehicles, and detecting anomalous behaviours in busy environments. The leading-edge techniques ....Automated acquisition of surveillance-camera network topology. The development of an automated system for acquisition of camera network topology is a crucial prerequisite to obtaining intelligent surveillance systems operating at the network level. Such systems will contribute improved methods for safeguarding Australia from terrorism and crime by facilitating the tracking of suspicious individuals and vehicles, and detecting anomalous behaviours in busy environments. The leading-edge techniques involved will also constitute smart information use of significant commercial value to Australian industry. Read moreRead less
Enhanced parameter estimation for multi-component fitting in computer vision. This project will benefit Australia's scientific knowledge and technology base in the area of computer vision. By contributing improved methods for parameter estimation applicable to a wide variety of technical problems, the project will aid the generation of improved software products in a wide variety of domains. Examples include: augmented reality systems, with which virtual reality artifacts may be immersed within ....Enhanced parameter estimation for multi-component fitting in computer vision. This project will benefit Australia's scientific knowledge and technology base in the area of computer vision. By contributing improved methods for parameter estimation applicable to a wide variety of technical problems, the project will aid the generation of improved software products in a wide variety of domains. Examples include: augmented reality systems, with which virtual reality artifacts may be immersed within real video; behaviour analysis in surveillance, in which complex, articulated 3D object motions may be characterised.Read moreRead less