Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol a ....Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol administration. Successful development of the technology will not only gain new knowledge in the key area of nanotechnology, but also lead to better inhalation therapy to benefit patients.Read moreRead less
Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung inf ....Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung infection and other serious health problems will benefit from an improved delivery of therapeutic dose at a much reduced cost. The technology is environmentally friendly as powder aerosol delivery does not require any harmful organic solvent to operate.Read moreRead less
High Gravity Precipitation of Nanoparticles for Pulmonary Drug Delivery. This collaborative project aims to explore the huge market potential of drug delivery by inhalation aerosols using nanoparticles. It will apply cutting edge nanotechnology to develop new techniques using high gravity to synthesise particles of biomaterials suitable for inhalation. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. Successful developme ....High Gravity Precipitation of Nanoparticles for Pulmonary Drug Delivery. This collaborative project aims to explore the huge market potential of drug delivery by inhalation aerosols using nanoparticles. It will apply cutting edge nanotechnology to develop new techniques using high gravity to synthesise particles of biomaterials suitable for inhalation. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. Successful development of the technology will position both Australia and the industry partner to take a lead in the application of this novel technology in pharmaceutical aerosols, and provides better inhalation therapy to benefit patients.Read moreRead less
Establishing the relationship between water characteristics and fouling of membranes used in water reuse. The project will result in the following significant benefits to the Australian and international partners: a state-of-the-art laboratory and semi-pilot system from which a full-scale system could be developed and tested, funded by the water industry; an outstanding research project for postgraduate students at the University of Technology, Sydney (UTS), Gwangji Institute of Science and Tech ....Establishing the relationship between water characteristics and fouling of membranes used in water reuse. The project will result in the following significant benefits to the Australian and international partners: a state-of-the-art laboratory and semi-pilot system from which a full-scale system could be developed and tested, funded by the water industry; an outstanding research project for postgraduate students at the University of Technology, Sydney (UTS), Gwangji Institute of Science and Technology, Korea (GIST) and Yale University; and fostering a culture of innovation in the wastewater industry in Australia, Korea and USA and contributing to the commercialization of research by UTS, GIST and YU.Read moreRead less
Fluidised bed biosorption-flocculation granular activated carbon (FBBSF-GAC) for membrane filtration in wastewater reuse. Water resource is limited and has been continuously decreasing. The idea of recycling and reusing of wastewater has been adopted for irrigation, industry and other non-potable uses. In Australia, wastewater reuse is now considered a key strategy for conserving water at national, state and local level. In this study, the proposed treatment unit is to produce a superior effluen ....Fluidised bed biosorption-flocculation granular activated carbon (FBBSF-GAC) for membrane filtration in wastewater reuse. Water resource is limited and has been continuously decreasing. The idea of recycling and reusing of wastewater has been adopted for irrigation, industry and other non-potable uses. In Australia, wastewater reuse is now considered a key strategy for conserving water at national, state and local level. In this study, the proposed treatment unit is to produce a superior effluent quality for water reuse while minimize membrane fouling of the membrane filtration system. Hence, it will benefit water industries globally and communities in Australia. There will be a major export opportunity from Australia to supply efficient, low-cost and sustainable flocculant together with an improved treatment system worldwide.Read moreRead less
A New Photocatalysis Hybrid System in Wastewater Treatment for Reuse. This project would particularly be useful to unreticulated sewage systems and small sewage treatment plants are prevalent in the coastal areas of NSW and Queensland and the interior parts of Northern Territory with small and isolated communities. Opportunities for demonstrating the successful application of this cost effective method of waste water treatment to appropriate stakeholders through participation in workshops, semin ....A New Photocatalysis Hybrid System in Wastewater Treatment for Reuse. This project would particularly be useful to unreticulated sewage systems and small sewage treatment plants are prevalent in the coastal areas of NSW and Queensland and the interior parts of Northern Territory with small and isolated communities. Opportunities for demonstrating the successful application of this cost effective method of waste water treatment to appropriate stakeholders through participation in workshops, seminars and events will be explored. The study can also be extended to small and medium sized industries in their wastewater treatment. The technology is of direct benefit within the Nation and also has significant export potential. Read moreRead less
Determination of the fate of dissolved organic nitrogen in biological nutrient removal (BNR) processes and development of appropriate treatment technologies. The aim of this project is to better characterise the dissolved organic nitrogen (DON) in sewage treatment plant influent, determine its fate in biological nutrient removal (BNR) plants, and to evaluate and develop an appropriate treatment technology.
As a result of tightening effluent N licence requirements for sewage treatment plants, ....Determination of the fate of dissolved organic nitrogen in biological nutrient removal (BNR) processes and development of appropriate treatment technologies. The aim of this project is to better characterise the dissolved organic nitrogen (DON) in sewage treatment plant influent, determine its fate in biological nutrient removal (BNR) plants, and to evaluate and develop an appropriate treatment technology.
As a result of tightening effluent N licence requirements for sewage treatment plants, the dissolved organic nitrogen (DON) fraction has become extremely important. In many cases, the DON forms the major fraction of the effluent N, and is constraining further reductions in licence specifications, and in some cases it is the cause of failure to meet licence.
DON is refractory (un-biodegradable), very poorly characterised, its fate in conventional biological treatment processes not known, and its eventual impact on the environment unknown. Considering its importance, it is critical that these issues are addressed. This proposal intends to address some of them.
This project is an APA(I) PhD student project.Read moreRead less
Application of the MIEXR DOC process to membrane hybrid systems for water reuse. Fresh water is increasingly scarce in Australia and wastewater reuse is being advocated as a strategy for both meeting our needs and protecting the environment. This research will test the magnetic ion exchange (MIEX) process as a pretreatment for a membrane-flocculation hybrid system (MFHS). MIEX will remove small and medium molecular weight organics and minimize membrane fouling. Large molecular weight organics, s ....Application of the MIEXR DOC process to membrane hybrid systems for water reuse. Fresh water is increasingly scarce in Australia and wastewater reuse is being advocated as a strategy for both meeting our needs and protecting the environment. This research will test the magnetic ion exchange (MIEX) process as a pretreatment for a membrane-flocculation hybrid system (MFHS). MIEX will remove small and medium molecular weight organics and minimize membrane fouling. Large molecular weight organics, suspended solids and micro-organisms will be removed by MFHS. This research will pioneer a novel hybrid system for treatment and reuse of domestic wastewater for non-drinking purposes and provide high quality research training of a doctoral student.Read moreRead less
Production of Biodegradable Polyhydroxyalkanoate Polymers using Advanced Biological Wastewater Treatment Process Technology. The aim of this project is to develop a sustainable process for producing biodegradable polyhydroxyalkanoate (PHAs)polymers from an innovative aerobic-anaerobic biological wastewater treatment process, ?treating? high strength food industry effluent. These biopolymers offer enormous potential for use as renewable and biodegradable thermoplastics.
It is proposed to inve ....Production of Biodegradable Polyhydroxyalkanoate Polymers using Advanced Biological Wastewater Treatment Process Technology. The aim of this project is to develop a sustainable process for producing biodegradable polyhydroxyalkanoate (PHAs)polymers from an innovative aerobic-anaerobic biological wastewater treatment process, ?treating? high strength food industry effluent. These biopolymers offer enormous potential for use as renewable and biodegradable thermoplastics.
It is proposed to investigate two process configurations, namely the sequencing batch reactor and a continuous two step anaerobic-aerobic reaction system. These will be studied at bench-scale. The outcomes include:
1. Determination of the optimum microbial conditions and key growth
parameters for the production of PHA.
2. Optimisation of the process configuration, operating strategies
and operating conditions to maximise the
production of PHA.
3. Assessment of the influence of the feed composition (e.g. VFA)
on the PHA composition (PHB/PHV).
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Healthier Water: Innovative Processes for Arsenic Removal and Sludge Management. Arsenic is a highly toxic metal found in drinking water in parts of Australia and in many parts of the world. The enforcement of stringent arsenic standard for drinking water calls for an effective treatment technology. In this study, an innovative and cost effective treatment system for arsenic removal will be developed for use in small community water supplies. This novel hybrid system consists of buoyant media f ....Healthier Water: Innovative Processes for Arsenic Removal and Sludge Management. Arsenic is a highly toxic metal found in drinking water in parts of Australia and in many parts of the world. The enforcement of stringent arsenic standard for drinking water calls for an effective treatment technology. In this study, an innovative and cost effective treatment system for arsenic removal will be developed for use in small community water supplies. This novel hybrid system consists of buoyant media flocculator and a newly-developed metal oxide coated media adsorption technique to achieve superior arsenic removal. A simple and safe disposal of arsenic sludge will also be established and tested.Read moreRead less