A Longitudinal Study Of Psychopathology In People With Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$999,803.00
Summary
This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combina ....This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combination of questionnaire survey and in depth interviews of the young adults and their families or carers to track the course of their mental health. The study commenced in 1990 with nearly 1000 young people with ID aged 4-18 years and their progress has been reviewed every 2-3 years in over 75% of the original group. During the next 5 years we plan to follow their mental health during the critical stage of young adult life. During this time there is the greatest risk of mental illnesses such as depression and schizophrenia and the stresses of adjusting to new daily occupations, independent living or residential care and social contact away from the family. We will be able to study the specific emotional and behavioural problems faced by young adults with the main known causes of ID such as Down, Fragile X, Prader Willi and William Syndromes, as well as those who have autism. The great benefit of a long term follow up study is that it allows us to study the links between earlier family environmental, psychological and biological factors and subsequent mental health problems. We can also demonstrate the impact that mental illness in a young person with ID has on the family and parental mental health. The findings have implications for better diagnosis, improved care and management, early intervention and prevention of these common severe and under recognized mental health problems in this disadvantaged group of young Australians and their families and carers.Read moreRead less
The Role Of UPF3B And Nonsense Mediated MRNA Decay Surveillance In The Pathology Of Intellectual Disability.
Funder
National Health and Medical Research Council
Funding Amount
$789,954.00
Summary
Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundam ....Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundamental importance.Read moreRead less
Still in my mind: Gurindji experience, location and visuality. This project will develop an innovative historical account of the effects of pictorial representation of Aboriginal identity, using visual, ethnographic and archival sources. It will investigate and critique the impact of ethno-centric codification through which Aboriginal peoples have been framed and refracted throughout the 19th century and into the 21st century, from a specific Gurindji standpoint.
Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education ....Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education sectors, it will provide a forward-looking and accessible public history, and utilise the potential of images to broaden contemporary debates about citizenship. Expected outcomes include a better public understanding of the pathways to citizenship, and enhanced engagement with Australian values and identity.Read moreRead less
Connecting Indigenous Community Photographies: a transnational case study. The project aims to conduct the first transnational comparison of Indigenous community-controlled photography, exploring Indigenous peoples’ ways of seeing and documenting their worlds. The project seeks to significantly advance Australian and global understanding of Indigenous vernacular photography through investigating formerly unexplored private collections of images created by Indigenous photographers during the mid ....Connecting Indigenous Community Photographies: a transnational case study. The project aims to conduct the first transnational comparison of Indigenous community-controlled photography, exploring Indigenous peoples’ ways of seeing and documenting their worlds. The project seeks to significantly advance Australian and global understanding of Indigenous vernacular photography through investigating formerly unexplored private collections of images created by Indigenous photographers during the mid 20th Century in four communities across three countries. One of the outcomes of the project is a nuanced visual history that cannot be excavated from other sources. The benefits of this project include public exhibitions, a book, symposiums, and a scholarly anthology that encourages the public’s connection with the past.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775489
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the developm ....Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the development of national identity through the diversity and richness of Australia's visual cultures. Read moreRead less
Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empi ....Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empirical basis for national training programs designed to create experts that are accurate, reliable, and continuously improving. Improving the training of experts will ensure the integrity of forensics as evidentiary tools available to police, lead to more reliable courtroom convictions and help safeguard Australia from terrorism and crime.Read moreRead less
How feedback can impair recognition judgments and undermine border security, criminal investigations, educational testing, and medical screening. If a customs officer learns that they have missed an explosive device while screening luggage, will this affect their judgment? In many scenarios, a person receives feedback about their recognition memory performance and has to try again without having another chance to study the material. Almost no research has examined the effects of feedback on reco ....How feedback can impair recognition judgments and undermine border security, criminal investigations, educational testing, and medical screening. If a customs officer learns that they have missed an explosive device while screening luggage, will this affect their judgment? In many scenarios, a person receives feedback about their recognition memory performance and has to try again without having another chance to study the material. Almost no research has examined the effects of feedback on recognition in the absence of opportunity for further study. This is problematic because many vitally important recognition decisions lack such opportunity. Using various scenarios (face recognition, security screening, multiple-choice testing, and medical screening) this project will demonstrate that feedback affects recognition performance differently depending on the nature of the recognition decision.Read moreRead less
Optimal strategies for collaborative visual search. The ability of individual operators to search for and detect targets is a weak link in many military, medical, and industrial operations. Teams of operators, however, can perform well even when individuals do not. This project aims to investigate a promising new eye-tracking technique, gaze-linking, that helps searchers collaborate efficiently by allowing each to know where the other is looking. This research builds on mathematical models of in ....Optimal strategies for collaborative visual search. The ability of individual operators to search for and detect targets is a weak link in many military, medical, and industrial operations. Teams of operators, however, can perform well even when individuals do not. This project aims to investigate a promising new eye-tracking technique, gaze-linking, that helps searchers collaborate efficiently by allowing each to know where the other is looking. This research builds on mathematical models of information processing to identify strategies that optimise gaze-linked collaboration, and is expected to develop principles for training gaze-linked searchers. Gaze-linking offers a promising, and potentially economical, technique for improving human performance, increasing efficiency and safety in a variety of tasks.Read moreRead less
Improving anti-salt crystallisation for solar-steam desalination. This project aims to solve a critical issue of solar-steam desalination by fundamental research. The solar-steam desalination technology offers an ideal strategy to utilize solar light as the energy source for desalination and water purification to produce affordable clean water. Photothermal materials play a key role in the desalination system to convert sunlight to heat and subsequently evaporate the saline water to generate ste ....Improving anti-salt crystallisation for solar-steam desalination. This project aims to solve a critical issue of solar-steam desalination by fundamental research. The solar-steam desalination technology offers an ideal strategy to utilize solar light as the energy source for desalination and water purification to produce affordable clean water. Photothermal materials play a key role in the desalination system to convert sunlight to heat and subsequently evaporate the saline water to generate steam as clean water. However, salt crystallization on the photothermal material surfaces severely limits the performance of the materials and clean water production. Solving this problem could accelerate the commercialisation and application of this technology, which will benefit millions of people worldwide.Read moreRead less