Behavioural And Microbial Risk Factors Associated With Bacterial Vaginosis In Young Women
Funder
National Health and Medical Research Council
Funding Amount
$290,032.00
Summary
Bacterial vaginosis (BV) is one of the commonest genital infections in women of reproductive age. Few data have determined the incidence of BV among young low risk women and the associated risk factors. This study aims to establish the incidence of BV in a cohort of young women and determine if BV is sexually transmitted. We hope this research will led to improvements in management and treatment of BV.
Optimising Large-scale Public Health Interventions To Control Neglected Tropical Diseases
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Neglected tropical diseases (NTD) are a group of health conditions that affect the poorest of the poor, particularly in remote and rural areas. They affect the most vulnerable communities and cause substantial, chronic health harms impairing personal and social development. Several debilitating NTD are common in remote indigenous communities and Pacific islands. I propose a series of studies to investigate new strategies to control NTD in large populations where these diseases are endemic.
LIFEPATH: Life-course Biological Pathways Underlying Social Differences In Healthy Ageing
Funder
National Health and Medical Research Council
Funding Amount
$470,466.00
Summary
Healthy ageing varies across society due to environmental, behavioural and social circumstances that affect peoples’ lives. To improve our ability to change this we will investigate suspected biological mechanisms over the life course. Using repeated blood samples collected during a large prospective study, we will measure a very large number of biological markers and analyse these combined with lifestyle and behavioural information to identify the modifiable predictors of healthy ageing.
Practice- And Policy-relevant Research In Skin Cancer Epidemiology, Prevention And Screening
Funder
National Health and Medical Research Council
Funding Amount
$483,402.00
Summary
This Fellowship will enable me to lead an internationally-competitive program of research in skin cancer epidemiology, prevention & screening that will lead to improved patient and population health through impacts on clinical practice and health policy. My aim is to lead paradigm-shifting contributions in: ? Genetic epidemiology of melanoma, ? Precision skin cancer prevention & screening, and ? Public health genomics for cancer prevention.
Post-genomic Surveillance For Communicable Disease Control
Funder
National Health and Medical Research Council
Funding Amount
$470,144.00
Summary
Genomic surveillance is now at the forefront of translational research due to recent significant advances in genomics and informatics, increasing demands for rapid detection of outbreaks and transformational impact of culture-independent testing on public health. This multi-disciplinary research will redefine existing paradigms, develop and evaluate novel systems for laboratory surveillance and offer insights into transmission dynamics of high-burden pathogens for Australia.
Genomics Dissection And Prevention Of Bacterial Transmission Events
Funder
National Health and Medical Research Council
Funding Amount
$891,290.00
Summary
This project aims at improving public health capacity to limit the spread of infectious diseases in hospital and community settings. The multi-disciplinary team of investigators will link epidemiological data with the finest resolution data from bacterial genomes in order to pinpoint events of infection transmission between individuals. Two high-burden pathogens (golden staph and food-borne Salmonella) will be used as exemplars of infectious diseases with different biology and modes of spread.
Understanding The Sources Of Campylobacter In Australia
Funder
National Health and Medical Research Council
Funding Amount
$546,720.00
Summary
Campylobacter is a key cause of foodborne disease in Australia, with rates of illness amongst the highest in the world. Our project brings together academic, government and industry partners to harness new genetic techniques to better identify sources and risk factors for Campylobacter infection. The project will assist health agencies to include genomics in public health, with findings directly informing government policies and industry practices to minimise disease caused by Campylobacter.
A New Genomic Frontier For Foodborne Disease Investigation In Australia
Funder
National Health and Medical Research Council
Funding Amount
$750,520.00
Summary
Foodborne diseases caused by bacteria such as Salmonella and Campylobacter are a huge public health problem, both in Australia and globally. Current methods used to investigate foodborne disease may not be sensitive enough to track foodborne outbreaks, and may not even detect them in the first place. We propose using cutting-edge molecular techniques to investigate foodborne outbreaks, and we think that using these methods will enable outbreaks to be interrupted at a much earlier stage.
Improving Skin Cancer Prevention: Motivating Preventive Behaviours Using Knowledge Of Personalised Genomic Risk Of Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$1,041,720.00
Summary
The aim of our study is to evaluate whether we can improve the Australian public’s skin cancer prevention behaviours, particularly reducing exposure to ultraviolet (UV) radiation, by giving personalised information about melanoma genetic risk. We will also explore the psycho-social, ethical, and economic implications of receiving this information. The results of our study are likely to influence the future of skin cancer prevention in Australia.
Investigation Of Candidate Aetiologic Organisms Of Bacterial Vaginosis In Diverse And Unique Epidemiological And Clinical Studies
Funder
National Health and Medical Research Council
Funding Amount
$564,438.00
Summary
Bacterial vaginosis (BV), a vaginal infection affecting 10% of Australian women, is an important cause of premature birth, yet its cause is unknown. We are conducting studies to understand the cause of BV in order to improve diagnosis and treatment.