Tailoring A Brief Sleep Intervention For Autism: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$401,475.00
Summary
Up to 86% of children with Autism Spectrum Disorder (ASD) experience behavioural sleep problems which have been shown to be associated with increased core ASD symptoms, increased rates of internalizing and externalizing disorders, and increased parental stress. The “Sleeping Sound” study is a novel behavioural sleep intervention that has shown much promise as a treatment to reduce sleep problems and improve mental health outcomes in children with ASD.
Understanding The Mechanisms Of Bleeding And Clotting Complications For Children On Extracorporeal Circuits.
Funder
National Health and Medical Research Council
Funding Amount
$1,113,385.00
Summary
Extracorporeal Membrane Oxygenation (ECMO) is advanced life support, which can save critically ill children. Significant bleeding occurs in 39%; clotting in 31% of children on ECMO; stroke in 12%. The biggest barrier to reducing these complications is the lack of understanding of how the bleeding/clotting system works in ECMO. This unique proposal uses the largest paediatric ECMO population in Australia and a multidisplinary expert team to develop a mechanistic understanding of these issues.
Adolescent Rural Cohort Study Hormones, Health, Education, Environments And Relationships
Funder
National Health and Medical Research Council
Funding Amount
$1,016,983.00
Summary
Adolescence is a time of major physical, emotional and social change, often characterised by risk taking and experimentation. Behaviours and decisions taken at this time of life will shape future health. This rural cohort study will for the first time will study the influence of pubertal hormones on behaviours, mental and physical health and general well being in adolescents.
Nitric Oxide On Cardio Pulmonary Bypass In Congenital Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$1,878,889.00
Summary
Children undergoing open heart surgery on a heart lung machine can experience serious side effects from the exposure to the artificial circulation during surgery and may have either prolonged need for life support in intensive care or even may suffer from long term complications. In this study we investigate the use of a new approach using nitric oxide, a anti-inflammatory gas, during surgery to reduce these side effects.
Nasal Highflow For Paediatric Acute Hypoxic Respiratory Failure
Funder
National Health and Medical Research Council
Funding Amount
$2,627,819.00
Summary
The burden of respiratory disease in children requiring intensive care admission is increasing despite better quality care in hospitals. This study investigates a new method, called nasal high flow, to support the breathing of children, that can be provided in regular children's wards in regional and metropolitan hospitals. The study anticipates to demonstrate that early intervention with nasal high flow reduces the need for intensive care admission.