Probing the function of protein molecular motors on nano-fabricated structures. The function of protein linear molecular motors, which are natural dynamic bio-nano-devices with a ubiquitous importance in multicellular organisms, will be 'probed' with purposefully designed nano-structures fabricated via photo- or Scanning Probe Microscopy Lithography, that is, flat polymeric surfaces with combinatorial combinations of physico-chemistries; and micro/nano-channels and nano-wells with critical dimen ....Probing the function of protein molecular motors on nano-fabricated structures. The function of protein linear molecular motors, which are natural dynamic bio-nano-devices with a ubiquitous importance in multicellular organisms, will be 'probed' with purposefully designed nano-structures fabricated via photo- or Scanning Probe Microscopy Lithography, that is, flat polymeric surfaces with combinatorial combinations of physico-chemistries; and micro/nano-channels and nano-wells with critical dimensions similar to the scale of the probed biomolecules. The project turns 'up-side down' the challenge of invasive nano-probing of biomolecules using it in an engineered manner. The fundamental understanding of linear molecular motors will impact on biomedical science and on the assessment of hybrid natural-artificial dynamic nano-devices.Read moreRead less
Nano-scale modification of gold surfaces for sensing mercury from gaseous effluents of alumina refineries. The Australian alumina industry contributes more than $5.4 billion export income annually. It is also a major driver of the rural economy with all but one of Australia's seven alumina refineries located in rural areas. In response to the industry's attempts to reduce the environmental impact of its processes, this project will conduct basic strategic research into the interaction between m ....Nano-scale modification of gold surfaces for sensing mercury from gaseous effluents of alumina refineries. The Australian alumina industry contributes more than $5.4 billion export income annually. It is also a major driver of the rural economy with all but one of Australia's seven alumina refineries located in rural areas. In response to the industry's attempts to reduce the environmental impact of its processes, this project will conduct basic strategic research into the interaction between mercury vapour and gold surfaces at the nano-level. Our principal aim is to develop mercury sensor technology suited to alumina refineries. This innovative technology will be a significant breakthrough in the control of mercury emissions and have many other applications.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989068
Funder
Australian Research Council
Funding Amount
$637,120.00
Summary
Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information g ....Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information gained is not accessible by any other method. The proposed equipment will be the first of this type in Australia and will complement existing surface science facilities. The project will enhance Australia's position in surface science internationally and a large number of projects will benefit from access to the equipment.Read moreRead less
Exploring the Dynamics of Nanostructure Self-Organisation during Compound Semiconductor Epitaxy. The application of LEEM to GaAs and InAs will be a world first, positioning Australia at the forefront of nanoscale self-organisation, leading to important international recognition and publicity. The spectacular movies obtained will revolutionise our basic understanding of compound semiconductor self-organisation and facilitate an improved control over nanostructure fabrication using MBE. This will ....Exploring the Dynamics of Nanostructure Self-Organisation during Compound Semiconductor Epitaxy. The application of LEEM to GaAs and InAs will be a world first, positioning Australia at the forefront of nanoscale self-organisation, leading to important international recognition and publicity. The spectacular movies obtained will revolutionise our basic understanding of compound semiconductor self-organisation and facilitate an improved control over nanostructure fabrication using MBE. This will generate entirely new device structures relevant to the frontier technologies of photonics and quantum information processing. The project will provide high level training for post-graduate and honours students in nanoscale characterisation and synchrotron science.Read moreRead less
Biodegradable immuno-therapeutic nanoparticles. The national benefit relates directly to Promoting and Maintaining Good Health through preventative healthcare as this project will develop a new vaccine delivery platform that will contribute to preventing a host of diseases such as viral infections and malaria. The health benefits of better vaccines directly enhance a Healthy Start to Life and Ageing Well. This area of nanoparticle therapies is a global 'hot spot' and this multi-disciplinary team ....Biodegradable immuno-therapeutic nanoparticles. The national benefit relates directly to Promoting and Maintaining Good Health through preventative healthcare as this project will develop a new vaccine delivery platform that will contribute to preventing a host of diseases such as viral infections and malaria. The health benefits of better vaccines directly enhance a Healthy Start to Life and Ageing Well. This area of nanoparticle therapies is a global 'hot spot' and this multi-disciplinary team could make huge and rapid progressions in this area of therapeutics. New intellectual property in the area of therapeutic particle production is the cornerstone of this project and could deliver lasting economic benefits through the creation of new health products and patents.Read moreRead less
Novel nanostructured alloy membranes for hydrogen permeation: Advanced materials technology for renewable energy. Hydrogen purification by alloy membranes is a key technology in maintaining the greenhouse gas emission low while using the fossil fuels including coal for energy generation. However, the alloys currently available for the membrane separation are mostly based on a costly precious metal palladium, making the application of the technology limited. The proposed non-equilibrium material ....Novel nanostructured alloy membranes for hydrogen permeation: Advanced materials technology for renewable energy. Hydrogen purification by alloy membranes is a key technology in maintaining the greenhouse gas emission low while using the fossil fuels including coal for energy generation. However, the alloys currently available for the membrane separation are mostly based on a costly precious metal palladium, making the application of the technology limited. The proposed non-equilibrium material processing will enable us to fabricate novel nanocomposite niobium-based alloys to which excellent hydrogen permeation characteristics are expected with high economic viability. Successful development of the proposed alloys could enhance the competitiveness of the Australian coal industry worldwide.Read moreRead less
Advanced products through multiscale microstructure engineering. The metals manufacturing industry is one of the most important in Australia. Future growth and sustainability of the sector is critically dependent on the development of innovative metal products and materials.. In this program Australia's leading research group in metal manufacturing will develop new products and processes through the controlled manipulation of the microstructure at a number of levels: from nano scale to macro s ....Advanced products through multiscale microstructure engineering. The metals manufacturing industry is one of the most important in Australia. Future growth and sustainability of the sector is critically dependent on the development of innovative metal products and materials.. In this program Australia's leading research group in metal manufacturing will develop new products and processes through the controlled manipulation of the microstructure at a number of levels: from nano scale to macro scale. The areas of application include the automotive industry, biomaterials, surface engineering and the emerging area of microforming technologiesRead moreRead less
Exploring the bio-nano interface in plants to enhance crop growth. This project aims to improve the delivery of nutrients and therapeutics to plants by understanding their interactions with nanomaterials. This will create new knowledge on the impact of air, water, and soilborne nanomaterials utilizing cutting-edge bio-nano characterization techniques, innovative lab testing, and high-throughput nanoparticle coating and screening. Expected outcomes of the project include 1) an understanding into ....Exploring the bio-nano interface in plants to enhance crop growth. This project aims to improve the delivery of nutrients and therapeutics to plants by understanding their interactions with nanomaterials. This will create new knowledge on the impact of air, water, and soilborne nanomaterials utilizing cutting-edge bio-nano characterization techniques, innovative lab testing, and high-throughput nanoparticle coating and screening. Expected outcomes of the project include 1) an understanding into how nanomaterial coating technologies impact nanomaterial properties, which will 2) shed light on how nanomaterials interact with plants, which leads to 3) breakthroughs in using nanomaterials to deliver nutrients, fertilizers, and pesticides to boost crop yields and productivity in Australian agriculture.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100900
Funder
Australian Research Council
Funding Amount
$366,000.00
Summary
Smart aptamer-guided nanoexosome as a novel biotechnology platform. This project aims to develop guided novel nanomaterials as a new biotechnological platform for in vivo targeted delivery of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) for gene editing. By systematically engineering the surface properties of natural nanovesicles known as exosomes, a novel nanotechnology platform should be established. The guided nano biotechnological platform should not only enable targete ....Smart aptamer-guided nanoexosome as a novel biotechnology platform. This project aims to develop guided novel nanomaterials as a new biotechnological platform for in vivo targeted delivery of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) for gene editing. By systematically engineering the surface properties of natural nanovesicles known as exosomes, a novel nanotechnology platform should be established. The guided nano biotechnological platform should not only enable targeted in vivo precision gene editing via CRISPR but also specific delivery of gene editing machinery across the blood brain barrier for better exploration of fundamental biology of the brain.Read moreRead less
ARC Nanotechnology Research Network. The field of nano scale science, engineering and technology (in short nanotechnology) is just emerging and it is predicted to make a major impact in all technologies and areas of society. Australian Nanotechnology Network intends to harness the combined Australian capability to enable Australia to take a leading role in this rapidly growing field.