Jet breakup of emulsions for the production of designer microparticulate drug delivery systems. Drug delivery systems are an important and growing part of the pharmaceutical and biotechnology market. The growth is estimated to be at 23% p.a. and is tied to the requirements for more precise and complex delivery profiles by highly potent drugs or vaccines (bioactives). To achieve the required level of control and precision, improved encapsulation technologies are needed to produce particles of a p ....Jet breakup of emulsions for the production of designer microparticulate drug delivery systems. Drug delivery systems are an important and growing part of the pharmaceutical and biotechnology market. The growth is estimated to be at 23% p.a. and is tied to the requirements for more precise and complex delivery profiles by highly potent drugs or vaccines (bioactives). To achieve the required level of control and precision, improved encapsulation technologies are needed to produce particles of a precise size and narrow size distribution. This project aims to develop an innovative technology for the production of superior uniformly sized particulate drug delivery systems for the delivery of the "next generation" bioactives.Read moreRead less
Ozone-Enhanced Particle Removal in Water Treatment. Combined ozonation/biologically active carbon filtration provides effective contaminant removal while minimizing disinfection by-product formation. However, the cost of installation in conventional water treatment plants is very high. This project will investigate the beneficial influence of ozonation on the micro-flocculation of small particles, with the aim to optimising particle removal by sedimentation prior to filtration. To do this, requi ....Ozone-Enhanced Particle Removal in Water Treatment. Combined ozonation/biologically active carbon filtration provides effective contaminant removal while minimizing disinfection by-product formation. However, the cost of installation in conventional water treatment plants is very high. This project will investigate the beneficial influence of ozonation on the micro-flocculation of small particles, with the aim to optimising particle removal by sedimentation prior to filtration. To do this, requires a clear understanding of how dissolved ozone interacts with particle surfaces for different water chemistries. The ideal outcome would be to develop a robust water treatment system that required BAC filtration only and eliminated the need for a conventional sand filtration stage as well.Read moreRead less
Multi-scale Process Modelling for Intelligent Control. Processing and manufacturing systems are inherently multi-scale in their behaviour. From the molecular scale to the enterprise-wide scale. This and other attributes of the individual models create difficulties in the design and control of such systems. This project will develop suitable multi-scale measures (metrics) for process models based on an object oriented assumption based modelling language. It will lead to enhanced intelligent contr ....Multi-scale Process Modelling for Intelligent Control. Processing and manufacturing systems are inherently multi-scale in their behaviour. From the molecular scale to the enterprise-wide scale. This and other attributes of the individual models create difficulties in the design and control of such systems. This project will develop suitable multi-scale measures (metrics) for process models based on an object oriented assumption based modelling language. It will lead to enhanced intelligent control strategies and improved operational performance through use of the most appropriate model. The work will focus on industrially important reaction and particulate processing systemsRead moreRead less
Scalable, high throughput microfluidic platforms for tissue specific biomaterials development and tissue genesis. The co-development of novel biomaterial platforms and new generation production methods for tissue analogues will provide the necessary stimulus for improved and more relevant methods of enhanced repair or regeneration of diseased or damaged tissues. These outcomes will result in faster time-to-market new generation therapeutic products for Australia and the world. These advances wil ....Scalable, high throughput microfluidic platforms for tissue specific biomaterials development and tissue genesis. The co-development of novel biomaterial platforms and new generation production methods for tissue analogues will provide the necessary stimulus for improved and more relevant methods of enhanced repair or regeneration of diseased or damaged tissues. These outcomes will result in faster time-to-market new generation therapeutic products for Australia and the world. These advances will have a significant impact on our healthcare costs and the quality of life for all Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100155
Funder
Australian Research Council
Funding Amount
$495,000.00
Summary
High-Speed Particle Image Velocimetry and Laser-Induced Fluorescence Facility. This state-of-the-art laser facility will increase our scientific understanding of industrial processes by providing valuable information on velocity, temperature and concentration profiles for rapidly changing flow fields. Previously it was not possible to do this, and the knowledge gained will be applied to develop more efficient and environmentally sustainable operations. For example, many current processes have hi ....High-Speed Particle Image Velocimetry and Laser-Induced Fluorescence Facility. This state-of-the-art laser facility will increase our scientific understanding of industrial processes by providing valuable information on velocity, temperature and concentration profiles for rapidly changing flow fields. Previously it was not possible to do this, and the knowledge gained will be applied to develop more efficient and environmentally sustainable operations. For example, many current processes have high energy input but scientific evidence suggests that it can be reduced if the embodied energy of the flow is properly utilised. Importantly, this utilisation often leads to increased yields and product quality. The facility will greatly assist researchers and industry collaborators in developing processes for the 21st century.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC150100019
Funder
Australian Research Council
Funding Amount
$4,571,797.00
Summary
ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows ....ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows with guidance from the centre’s industrial partners. The centre’s expected legacy is a unique research and training facility, designed for future integration into a microscale LNG plant. The anticipated research and training outcomes will help to ensure Australia plays a leading role in future global LNG developments.Read moreRead less
Discrete Element Method for Analysis and Design of Pharmaceutical Encapsulation. Tablets represent the preferred method of dose delivery in the pharmaceutical industry, with over 80% of the market. PressFit - gelcaps have recently been developed, which encase a tablet core within a gelatin coating. The product combines the consumer appeal of capsules with the processing convenience of tablets, and provides a high degree of tamper-resistance. An important issue is that the caplets are required ....Discrete Element Method for Analysis and Design of Pharmaceutical Encapsulation. Tablets represent the preferred method of dose delivery in the pharmaceutical industry, with over 80% of the market. PressFit - gelcaps have recently been developed, which encase a tablet core within a gelatin coating. The product combines the consumer appeal of capsules with the processing convenience of tablets, and provides a high degree of tamper-resistance. An important issue is that the caplets are required to have very precise dimensional precision, an issue not previously of high priority for tabletting . This project seeks to enhance the competitive advantage of this new technology, through a combination of advanced mathematical modeling supported by experiments.Read moreRead less
Advanced modelling and optimisation of Underground Coal Gasification. The last decade is characterised by increasing interest of many countries in obtaining and developing Underground Coal Gasification (UCG) technologies. Recent long-term successful trial in Chinchilla has proven that the technology is ready for commercial use but the fundamental research into UCG is needed for further improvement of the technology performance in commercial applications. The major goal of this project is in comb ....Advanced modelling and optimisation of Underground Coal Gasification. The last decade is characterised by increasing interest of many countries in obtaining and developing Underground Coal Gasification (UCG) technologies. Recent long-term successful trial in Chinchilla has proven that the technology is ready for commercial use but the fundamental research into UCG is needed for further improvement of the technology performance in commercial applications. The major goal of this project is in combining most recent advances in combustion modelling with practical UCG operations and developing new advanced models specifically for UCG diagnostics and optimisation. The project outcomes involve: better understanding and optimisation of UCG processes and further development of advanced modelling techniques.
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Cloud scheduling and management of energy systems with real-time support. This project aims to research cloud scheduling and management of modern energy systems with real-time communication support. The approach consists of optimisation with balanced benefits for customers, aggregators and network service providers for modern energy systems; real-time communication support for unified energy scheduling and management over many microgrids; and cloud energy scheduling and management with deadline ....Cloud scheduling and management of energy systems with real-time support. This project aims to research cloud scheduling and management of modern energy systems with real-time communication support. The approach consists of optimisation with balanced benefits for customers, aggregators and network service providers for modern energy systems; real-time communication support for unified energy scheduling and management over many microgrids; and cloud energy scheduling and management with deadline guarantee. This project is expected to facilitate increasing deployment of disruptive energy technologies on a massive scale, create opportunities for energy industries, and maintain Australia’s leading position in renewable energy.Read moreRead less
Advanced Stability Sensor for Anaerobic Digestion Processes. Australia is firmly committed to energy reduction and production, where possible, renewable energy production. Anaerobic digestion is the only in-use wastewater treatment option that not only can have net zero energy consumption, but that actually produces energy. This energy is from renewable carbon sources is therefore a zero contributor to greenhouse gases. Australia has some of the strongest environmental limit laws in the world. ....Advanced Stability Sensor for Anaerobic Digestion Processes. Australia is firmly committed to energy reduction and production, where possible, renewable energy production. Anaerobic digestion is the only in-use wastewater treatment option that not only can have net zero energy consumption, but that actually produces energy. This energy is from renewable carbon sources is therefore a zero contributor to greenhouse gases. Australia has some of the strongest environmental limit laws in the world. While this is reasonable - given our sensitive environment -assisting industry in meeting those limits in a cost effective manner is a priority. Given sufficient process stability and transparency, anaerobic digestion is a low capital and operating cost option. Read moreRead less