Flow structures and transport: predictability and control. Moving flow structures (the boundary of an eddy, the flow interface between two fluids) are crucial in fluid mixing and in the transport of heat, pollutants and nutrients. This project will analyse their roles in improving predictions of spreading extents and rates for geophysical-scale problems, and in controlling transport at the micro-scale. Inaccuracies in currently available numerical diagnostics for transport prediction will be com ....Flow structures and transport: predictability and control. Moving flow structures (the boundary of an eddy, the flow interface between two fluids) are crucial in fluid mixing and in the transport of heat, pollutants and nutrients. This project will analyse their roles in improving predictions of spreading extents and rates for geophysical-scale problems, and in controlling transport at the micro-scale. Inaccuracies in currently available numerical diagnostics for transport prediction will be comprehensively evaluated via comparison with recent exact models. Analytical methods for quantifying transport under unsteady flow protocols will be developed, and used to answer questions on controlling transport in microfluidic applications in conjunction with experimentalists.Read moreRead less
A coupled finite volume method for viscoelastic flow problems on highly-skewed unstructured meshes: a computational rheology revolution. Commercial tools are unavailable for 21st century industry to analyse complex flow processes involving viscoelastic materials. Using fabrication of microstructured polymer optical fibre as a key case study, a coupled finite volume methodology holds the key for the next generation of computational rheology simulators.
Exploring new tools in nonlinear filtering and control. The conceptual advances with new design rules to be developed in the area of nonlinear filtering and control. Major benefits of this project will be its direct applications to state estimation and control problems in automobile, manufacturing, military hardware and medical device industries, and its increased capacity of contact research.
A multiplex microscope platform to define molecular events in fluid systems. This project aims to develop a novel microscopy platform that will enable the visualisation and quantification of molecular events occurring under fluid shear stress. The project will generate new knowledge in platelet biology that will allow characterisation and prediction of key molecular and morphological changes occurring across a blood thrombus under flowing conditions as found in the blood vessels. These new tools ....A multiplex microscope platform to define molecular events in fluid systems. This project aims to develop a novel microscopy platform that will enable the visualisation and quantification of molecular events occurring under fluid shear stress. The project will generate new knowledge in platelet biology that will allow characterisation and prediction of key molecular and morphological changes occurring across a blood thrombus under flowing conditions as found in the blood vessels. These new tools and the imaging platform will have applications for researchers wishing to visualise small and rapid molecular events in four dimensions (length, width, height and across time) under fluid shear stress, which is applicable across a range of industries. The project expects to deliver the next generation of intravital microscopes that can visualise and quantify events in a challenging flow environment.Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Developing novel aerosol inhalers for pulmonary drug delivery from the fundamental understanding of powder dispersion mechanisms. The project seeks to understand how powder aerosol inhalers can be significantly improved. The outcome will provide therapeutic benefits to the Australian community for better treatment of respiratory diseases and facilitate environmentally friendly technology since these inhalers do not require any harmful organic solvents to operate.
Reliable and efficient algorithms for modelling dynamical systems from data. Mathematical and computational models are increasingly important in diverse areas of science and engineering including aircraft and automotive design, robotics, medical sensing, and biology. However, finding an accurate model remains a difficult task. This project will develop new methods to reliably find highly accurate models from recorded data.
A New Approach to High-Performance Control of Nonlinear Systems. The coming generation of robots are highly mobile and will interact significantly with their environment, each other, and human collaborators. However, this leads to highly coupled nonlinear dynamical behaviour, and achieving accurate and reliable control of these systems is pushing current control theory to breaking point. This project aims to develop a new approach to control of nonlinear systems based on contraction theory and c ....A New Approach to High-Performance Control of Nonlinear Systems. The coming generation of robots are highly mobile and will interact significantly with their environment, each other, and human collaborators. However, this leads to highly coupled nonlinear dynamical behaviour, and achieving accurate and reliable control of these systems is pushing current control theory to breaking point. This project aims to develop a new approach to control of nonlinear systems based on contraction theory and convex optimisation, extending the power of optimisation-based control from linear to non-linear systems. The project is expected to lead to new theoretical developments, constructive algorithms and software, and experimental demonstrations on a range of platforms including bipedal walking robots and underwater robots.Read moreRead less
Advanced coverage control techniques for mobile networked systems. This project aims to efficiently control individual mobile sensors and actuators to achieve network-wide coverage quality for monitoring and control of industrial and environmental processes. Coverage control of mobile networked systems is important in control engineering due to the growing use of mobile robots and mobile wireless networks for sensing coverage and monitoring. The project will develop techniques for coverage contr ....Advanced coverage control techniques for mobile networked systems. This project aims to efficiently control individual mobile sensors and actuators to achieve network-wide coverage quality for monitoring and control of industrial and environmental processes. Coverage control of mobile networked systems is important in control engineering due to the growing use of mobile robots and mobile wireless networks for sensing coverage and monitoring. The project will develop techniques for coverage control of mobile networks which are expected to solve industrial control problems in the defence, communications and robotics industries and manage the environment.Read moreRead less
Control and state estimation in the next-generation interconnected systems. This project aims to develop a systematic and efficient approach to address fundamental challenges in control and secure state estimation in the next-generation interconnected systems. Control and state estimation in high-tech systems is an emerging area of control engineering. The importance of this area is quickly increasing due to the growing use of the next-generation interconnected systems, in which physical and hig ....Control and state estimation in the next-generation interconnected systems. This project aims to develop a systematic and efficient approach to address fundamental challenges in control and secure state estimation in the next-generation interconnected systems. Control and state estimation in high-tech systems is an emerging area of control engineering. The importance of this area is quickly increasing due to the growing use of the next-generation interconnected systems, in which physical and high-tech components are interacting in complex networks. The project is expected to have direct applications in the management of energy networks, and in industrial control and secure state estimation problems in the defence, communications, and automobile industries.Read moreRead less