This study investigates how much an individual's genes and environment account for the wide variation in brain structure and function. Using brain imaging we examine in what way the connectivity of the brain of identical and non-identical twins is the same or different from that of their co-twin, and carry out analysis of their DNA to identify some of the genes involved. This will provide fundamental information on genetic mechanisms influencing variation in brain structure and function.
An investigation of meaning negotiation in electronic discourse. This project investigates the use of collaborative electronic exchanges between language students in Indonesian and Queensland schools to enhance language and inter-cultural development. The chief investigators will develop a new model of discourse appropriate to such asynchronous communication (e-mail and forums), as well as investigate developments in technological literacy. Other outcomes will include guidelines for creating pra ....An investigation of meaning negotiation in electronic discourse. This project investigates the use of collaborative electronic exchanges between language students in Indonesian and Queensland schools to enhance language and inter-cultural development. The chief investigators will develop a new model of discourse appropriate to such asynchronous communication (e-mail and forums), as well as investigate developments in technological literacy. Other outcomes will include guidelines for creating practical technology-mediated tasks, and protocols for establishing and maintaining electronic tandem exchanges with a developing country. Results will be reported to the Industry Partner and relevant educational authorities and published in national and international journals such as ARAL, Babel and CALL Journal.Read moreRead less
A Prospective Study Of Language Impairment And Recovery Following Surgery For Brain Tumours
Funder
National Health and Medical Research Council
Funding Amount
$861,342.00
Summary
This multi-site project will investigate the incidence and nature of post-operative language difficulties (aphasia) in patients following surgery for left hemisphere primary brain tumours. It will provide comprehensive data concerning risk factors for post-surgical aphasia in Australian patients, in addition to important information about the brain lesions responsible for its various clinical presentations. This information will be used to generate recommendations for clinical practice.
Normal And Abnormal Development Of Brain Wiring And Its Impact On Brain Function
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
My laboratory is striving to understand how the patterns of neuronal connections form in the developing brain and how these underpin the functions of the brain throughout life. We use high-field magnetic resonance imaging to measure brain wiring and we investigate the genetic and environmental mechanisms causing developmental brain disorders that result in intellectual disability, autism, epilepsy and some mental illnesses.
The measurement of primary traits in second language oral proficiency in second language acquisition research. The proposed research will help to inform high-quality learning outcomes for international ESL (English as a Second Language) students and students who study Japanese or Spanish as a second language in Australian universities. Improved effectiveness in current second language teaching pedagogy will result from a deeper understanding of the role that the key language traits (syntactic co ....The measurement of primary traits in second language oral proficiency in second language acquisition research. The proposed research will help to inform high-quality learning outcomes for international ESL (English as a Second Language) students and students who study Japanese or Spanish as a second language in Australian universities. Improved effectiveness in current second language teaching pedagogy will result from a deeper understanding of the role that the key language traits (syntactic complexity, lexical range, accuracy and fluency) play in the attainment of advanced proficiency. Read moreRead less
Uncovering The Neural Mechanisms Of Obsessive-compulsive Disorder Using Brain Modelling
Funder
National Health and Medical Research Council
Funding Amount
$581,628.00
Summary
Obsessive-compulsive disorder (OCD) is an incurable mental illness and current therapies only mitigate its symptoms for a portion of individuals. Thus, there is a need to identify the neural causes of OCD to develop personalised therapies. We will combine mathematical modelling, computer simulations, and clinical and neuroimaging data to develop the first model of OCD. Outcomes from this study will enable targeted OCD research and the discovery of brain mechanisms supporting treatment response.
Dopamine Neuron Ontogeny: Convergent Neurobiological Pathway For Risk Factors Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$337,214.00
Summary
Schizophrenia is associated with changes in dopamine (a signalling molecule in the brain). These changes are present prior to psychosis, suggesting they begin early in development. Our aims are to manipulate key factors in the development of brain dopamine systems to clarify their role in psychosis and schizophrenia. This work has the potential to identify early brain changes that lead to schizophrenia, which in turn may generate better diagnoses and outcomes for people with this disorder.
The world through the prism of language: a cross-linguistic view of genders, noun classes, and classifiers. Australia is one of the most multilingual and multicultural countries in the world, with several hundred indigenous and immigrant languages. Noun classification devices - ranging from gender systems in familiar Indo-European languages to numeral classifiers in Southeast Asian languages - offer a unique insight into people's categorisation of the world around them. In-depth knowledge of how ....The world through the prism of language: a cross-linguistic view of genders, noun classes, and classifiers. Australia is one of the most multilingual and multicultural countries in the world, with several hundred indigenous and immigrant languages. Noun classification devices - ranging from gender systems in familiar Indo-European languages to numeral classifiers in Southeast Asian languages - offer a unique insight into people's categorisation of the world around them. In-depth knowledge of how speakers of different languages classify objects around them will promote intercultural understanding within Australia and world-wide, allowing us to overcome potential miscommunications due to different language backgrounds, and advancing our understanding of the region and the world (within the National Priority 'Safeguarding Australia'). Read moreRead less
Centre For Research Excellence In Speech And Language Neurobiology (CRE-SLANG)
Funder
National Health and Medical Research Council
Funding Amount
$2,491,340.00
Summary
Half a million Australian children have a speech/language disorder, tripling their changes of poor academic outcomes, limited employment options and social isolation. Current speech therapy is limited, focusing on symptoms and ignoring evidence on underlying aetiologies. By identifying and translating findings on new genes and brain pathways leading to speech and language disorders, we will transform detection, diagnosis, prognosis and genetic counselling of affected children and their families.
Through the eyes of the Chinese: Attitudes to and opinions of Australia and their influence on Sino-Australian business exchange. The outcomes of this research will have significant policy implications for the Australian government and business sectors in terms of improving intercultural understanding, facilitating bilateral trade, unlocking the potential of the Chinese market, as well as increasing economic efficiency. The capacity of Australian businesses to engage with China will be substanti ....Through the eyes of the Chinese: Attitudes to and opinions of Australia and their influence on Sino-Australian business exchange. The outcomes of this research will have significant policy implications for the Australian government and business sectors in terms of improving intercultural understanding, facilitating bilateral trade, unlocking the potential of the Chinese market, as well as increasing economic efficiency. The capacity of Australian businesses to engage with China will be substantially improved by enhancing our knowledge base about the individual, social, and national factors that facilitate and inhibit engagement in Sino-Australian business relations and exchange. Findings from this reserch will also inform the international development in education and training, tourism and technology in Australia.Read moreRead less