The Breast Cancer Biospecimen Resource will consist of stored samples of the majority of newly diagnosed breast cancers in NSW and through the Australian and New Zealand Breast Cancer Trials Group together with accurate, prospectively tracked clinical data on each specimen. This facility will serve as a model for extension of similar procedures to other common Australian cancers including cancers of the lung, bowel, prostate and melanoma. Research that is facilitated by this Resource holds real ....The Breast Cancer Biospecimen Resource will consist of stored samples of the majority of newly diagnosed breast cancers in NSW and through the Australian and New Zealand Breast Cancer Trials Group together with accurate, prospectively tracked clinical data on each specimen. This facility will serve as a model for extension of similar procedures to other common Australian cancers including cancers of the lung, bowel, prostate and melanoma. Research that is facilitated by this Resource holds real promise for improving patient selection for treatment. This will return a significant humanitarian and cost saving benefit. In addition this advance would also maximise the benefit of population mammographic screening.Read moreRead less
The Trans Tasman Radiation Oncology Group is an experienced research group conducting cancer clinical trials involving radiotherapy (RT) in order to improve cure rates, quality of life and to reduce side-effects of treatment. Fifty per cent of all cancer patients need RT as part of their treatment. The aim of the proposal is to strengthen the quality and safety of RT trials by (a) enabling rapid review and checking of treatment by electronic means and (b) improve trial design.
Availability of ethically consented, clinically annotated human cancer tissue is a key determinant of the international competitiveness of Australian biomedical researchers. This project will provide a structured national network to collect, process and disseminate tumour tissue; strategically target specific tumour types such as mesothelioma and rare paediatric tumours that can only be collected in substantial numbers through the formation of such a network and provide infrastructure that can b ....Availability of ethically consented, clinically annotated human cancer tissue is a key determinant of the international competitiveness of Australian biomedical researchers. This project will provide a structured national network to collect, process and disseminate tumour tissue; strategically target specific tumour types such as mesothelioma and rare paediatric tumours that can only be collected in substantial numbers through the formation of such a network and provide infrastructure that can be contracted by clinical and translational researchers. The project builds on a wealth of experience in tissue banking, large-scale molecular genetic and genomic studies in breast, ovarian, colorectal cancers and mesothelioma, and on an established consortium _ the Australasian Biospecimen Network.Read moreRead less
Australian Prostate Cancer Collaboration (APCC) Bio-Resource
Funder
National Health and Medical Research Council
Funding Amount
$2,310,000.00
Summary
The Australian Prostate Cancer Collaboration (APCC), supported by the Commonwealth Bank, Prostate Cancer Foundation of Australia and Andrology Australia, has been developing an Australia-wide network of prostate tissue banks and associated clinical databases for the past 3 years. The concept of this innovative project is to establish “nodes” or branches of the tissue bank in each State where tissues are collected and to coordinate the use of this material from a central committee or “head office ....The Australian Prostate Cancer Collaboration (APCC), supported by the Commonwealth Bank, Prostate Cancer Foundation of Australia and Andrology Australia, has been developing an Australia-wide network of prostate tissue banks and associated clinical databases for the past 3 years. The concept of this innovative project is to establish “nodes” or branches of the tissue bank in each State where tissues are collected and to coordinate the use of this material from a central committee or “head office”. A website has been established (www.apccbioresource.org.au) that is the national face of this ‘virtual’ national tissue bank and 7 State-based tissue bank consortiums are participating in this venture. The goal of this ‘virtual bank’ or network is to further enhance the national research effort by facilitating greater collaboration nationally and providing better access to, and optimal utilisation of, the clinical material available to facilitate improvements in prostate cancer management. Operational support for the nodes is critical for the success of a national Bio-Resource.Read moreRead less
The Australian Phenome Bank will establish a frozen sperm bank, database, and training program to enable access by the research community to new strains of genetically modified mice. Efficient access to diverse strains, provided by the Phenome Bank, will be critical for translating the human genome sequence into an understanding of specific mechanisms regulating all the body organ systems in health and disease, and for developing new disease prevention and treatment approaches.
Protocol Development, Web-based Data Collection And Data Quality For All Cancer Cooperative Trials Groups
Funder
National Health and Medical Research Council
Funding Amount
$1,840,000.00
Summary
Each year, 85,000 Australian develop cancer and 35,000 die of it. The Clinical Oncological Society of Australia and nine Australian cancer trials groups run studies that test new and better ways of preventing, curing, treating and palliating people affected by cancer. This grant will help these groups start trials faster; run them more efficiently; coordinate quality assurance; and standardize operating procedures. This grant will enable collaboration that increases the speed, efficiency and qua ....Each year, 85,000 Australian develop cancer and 35,000 die of it. The Clinical Oncological Society of Australia and nine Australian cancer trials groups run studies that test new and better ways of preventing, curing, treating and palliating people affected by cancer. This grant will help these groups start trials faster; run them more efficiently; coordinate quality assurance; and standardize operating procedures. This grant will enable collaboration that increases the speed, efficiency and quality of cancer research to lessen the suffering of people affected by cancer.Read moreRead less
The Australasian Leukaemia And Lymphoma Group (ALLG) Trial Centre
Funder
National Health and Medical Research Council
Funding Amount
$790,000.00
Summary
Lymphoma, leukaemia and related cancers of the blood affect thousands of Australians, including children. The Australasian Leukaemia and Lymphoma Group, a network of clinical and laboratory haematologists, will integrate laboratory research to discover new approaches to treatment, with clinical trials to test the safety and effectiveness of the new treatments. This approach should accelerate the research and maximise patient and community benefits.