The END RHD CRE: Developing An Endgame For Rheumatic Heart Disease In Australia
Funder
National Health and Medical Research Council
Funding Amount
$2,601,147.00
Summary
Rheumatic heart disease (RHD) is caused by an abnormal immune reaction to some bacterial infections. Although RHD is rare in developed countries, Indigenous Australians still live with the burden of RHD. The END RHD CRE will explore risk factors for RHD, prevention with antibiotics, management of RHD and the potential for vaccine development. Individuals and communities experiencing RHD are integral partners to this work. The CRE will establish a strategy for ending RHD in Australia.
Innovative Health Programs To Reduce Inequality In Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
As part of his Senior NHMRC Fellowship, Prof Simon Stewart, a world-renowned health services researcher, will lead an internationally linked team of researchers from a broad range of health disciplines to undertake a program of research designed to improve the lives of those most vulnerable to heart disease and poor health outcomes. His program of research will focus on Indigenous Australians, patients with complex forms of heart disease and urban African communities in economic transition.
Global dementias: Examining structural vulnerability and dementia outcomes. This project aims to examine the social and cultural dimensions of dementia by using a comparative ethnographic approach to examine the experiences of people living with dementia in Australia, Malaysia and India. The project expects to generate new anthropological knowledge about structural inequalities by examining how dementia is responded to in diverse geographic, cultural and social settings. Expected outcomes of thi ....Global dementias: Examining structural vulnerability and dementia outcomes. This project aims to examine the social and cultural dimensions of dementia by using a comparative ethnographic approach to examine the experiences of people living with dementia in Australia, Malaysia and India. The project expects to generate new anthropological knowledge about structural inequalities by examining how dementia is responded to in diverse geographic, cultural and social settings. Expected outcomes of this project include the creation of a new evidence-base on dementia and the production of briefing documents to guide global health frameworks. The project should provide significant benefits for people living with dementia by providing locally-relevant strategies to respond to dementia and resultant disability.Read moreRead less
Emerging from the shadows: the evaluation of intervention strategies to reduce social isolation amongst the aged. Social isolation imposes a high cost on affected individuals and the community at large. This project will determine what interventions work in addressing social isolation amongst the older population.
The transition from secondary school to adulthood: Experiences and life outcomes for youth with an intellectual disability and their families. This project seeks to explore the challenges faced and outcomes achieved by students with an intellectual disability as they move from secondary school into adult life. The study will investigate the factors at an individual, educational, family, and societal level which positively and adversely affect outcomes for young people with an intellectual disab ....The transition from secondary school to adulthood: Experiences and life outcomes for youth with an intellectual disability and their families. This project seeks to explore the challenges faced and outcomes achieved by students with an intellectual disability as they move from secondary school into adult life. The study will investigate the factors at an individual, educational, family, and societal level which positively and adversely affect outcomes for young people with an intellectual disability and their families. Family impacts can include significant loss of income as parents may have to cease employment to care for their young adult who has limited employment or day placement options. Gaining the knowledge to minimise the disruption to family life, which often occurs at this time of transition, will lead to strengthening Australia's social and economic fabric.Read moreRead less
Driving performance and self-regulation practices in drivers with dementia . Despite the high prevalence of dementia in older drivers, a substantial gap remains in the evidence regarding the natural progression of the disease and its impact on fitness to drive. This project will use a combination of real-time, in-vehicle driver monitoring devices and a state-of-the-art driving simulator. Together, these will objectively measure natural driving patterns and self-regulation practices, and provide ....Driving performance and self-regulation practices in drivers with dementia . Despite the high prevalence of dementia in older drivers, a substantial gap remains in the evidence regarding the natural progression of the disease and its impact on fitness to drive. This project will use a combination of real-time, in-vehicle driver monitoring devices and a state-of-the-art driving simulator. Together, these will objectively measure natural driving patterns and self-regulation practices, and provide a comprehensive assessment of driving performance for drivers with mild dementia and a comparison group without dementia. The project will create a partnership between leading researchers, clinicians and policy makers in order to provide an answer to a complex problem.Read moreRead less
The nature, extent and effect of infant removal by child protection. This project aims to provide new knowledge about the nature, extent and effect of removals of babies from their parents in Australia. Removal is the highest level of intervention by the child protection system, and one which some mothers experienced on multiple occasions. Little is known, however, about its incidence and effects, nor whether there are over-represented groups (e.g. Aboriginal mothers and babies) who would respon ....The nature, extent and effect of infant removal by child protection. This project aims to provide new knowledge about the nature, extent and effect of removals of babies from their parents in Australia. Removal is the highest level of intervention by the child protection system, and one which some mothers experienced on multiple occasions. Little is known, however, about its incidence and effects, nor whether there are over-represented groups (e.g. Aboriginal mothers and babies) who would respond to targeted interventions. This project aims to identify appropriate early intervention and prevention strategies, preventing the need for babies to spend their whole childhood in care at great financial and societal cost.Read moreRead less
Quantitative multi-modal optical imaging of deep tissue. This project aims to create new tools to quantify the structural and functional properties of tissue. Combining multiple optical imaging technologies (multi-modal) into a single, miniaturised probe, these tools could enable physiologists and biomedical researchers to obtain new insight into disease. Encasing the highly miniaturised probe within a medical needle is aimed to allow insertion of the 'needle probe' deep into tissue, extending o ....Quantitative multi-modal optical imaging of deep tissue. This project aims to create new tools to quantify the structural and functional properties of tissue. Combining multiple optical imaging technologies (multi-modal) into a single, miniaturised probe, these tools could enable physiologists and biomedical researchers to obtain new insight into disease. Encasing the highly miniaturised probe within a medical needle is aimed to allow insertion of the 'needle probe' deep into tissue, extending optical imaging to areas not previously accessible. The project could develop novel quantification models to allow longitudinal assessment and comparison between subjects. Validating the tools with specific biomarkers, it could provide outcomes in breast and liver cancer, and a framework to explore other diseases.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989759
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting a ....Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries and will generate science to support and stimulate domestic industry, enhance the domestic knowledge base and international research profile, train students and future synchrotron scientists and foster domestic and international collaborations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100009
Funder
Australian Research Council
Funding Amount
$1,064,000.00
Summary
Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications. Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications: Ultra-high field magnetic resonance imaging provides unique high contrast images at previously inaccessible levels of resolution (<0.1mm). It non-invasively provides unprecedented information on chemical and biochemical processes including functional biological mechanisms. This infrastructure will be the focal point for ....Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications. Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications: Ultra-high field magnetic resonance imaging provides unique high contrast images at previously inaccessible levels of resolution (<0.1mm). It non-invasively provides unprecedented information on chemical and biochemical processes including functional biological mechanisms. This infrastructure will be the focal point for more than 100 academics and HDR students. It will take Australia to the forefront of magnetic resonance imaging capability as well as providing unique insights into diffusion and electrophoretic problems central to designing next generation energy storage. Outcomes will range from agricultural advances, higher performing batteries, and more effective cancer treatments as well advancing Australia's fundamental scientific capabilities.Read moreRead less