Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
The Role Of Melanoma Tumour Antigen P97 (Melanotransferrin) In Melanoma Tumourigenesis.
Funder
National Health and Medical Research Council
Funding Amount
$563,242.00
Summary
The Role of Melanoma Tumour Antigen p97 (Melanotransferrin) in Melanoma Tumourigenesis Melanotransferrin (MTf) is a homologue of the iron transport protein, transferrin, and was one of the first well characterised melanoma tumour antigens. Our published studies have shown that MTf plays an important role in melanoma tumourigenesis in vivo. In this proposal, we will assess if it is associated with melanoma progression in patient samples and examine its role in melanoma growth and metastasis.
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.
Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si a ....Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si alleviates stress in wheat, from gene to farm scale, providing cost-benefit analysis and a best–practice toolbox for implementation by farmers. Outcomes are anticipated to provide a cheaper and more environmentally sustainable solution to issues of water scarcity and yield losses to pests in Australia’s leading crop.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100030
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub in Intelligent Robotic Systems for Real-Time Asset Management. This hub aims to transform the way assets and infrastructure are managed by developing new capabilities for intelligent robotic systems for inspection, monitoring, and maintenance. The hub expects to generate new knowledge in robotics and associated fields including sensing, planning, data processing, and machine learning using interdisciplinary approaches and tight collaboration between academia and industry. The ex ....ARC Research Hub in Intelligent Robotic Systems for Real-Time Asset Management. This hub aims to transform the way assets and infrastructure are managed by developing new capabilities for intelligent robotic systems for inspection, monitoring, and maintenance. The hub expects to generate new knowledge in robotics and associated fields including sensing, planning, data processing, and machine learning using interdisciplinary approaches and tight collaboration between academia and industry. The expected outcomes are robots with the ability to autonomously collect data for integration into a digital twin that provides a real-time representation of the true state of a physical asset. The benefits include both improved asset management and establishing Australia as a leading manufacturer of advanced robotic systems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100155
Funder
Australian Research Council
Funding Amount
$370,000.00
Summary
An Ultra-wideband Radio Receiver for the Parkes 64-metre Radio Telescope. An ultra-wideband radio receiver for the Parkes 64-metre radio telescope: This project aims to construct a state-of-the-art ultra-wide-band receiver and signal processing system for the Parkes 64-metre radio telescope. The receiver will operate across the entire 700 megahertz to four gigahertz band with outstanding sensitivity and polarimetric performance, providing a unique capability for high-time-resolution wide-bandwid ....An Ultra-wideband Radio Receiver for the Parkes 64-metre Radio Telescope. An ultra-wideband radio receiver for the Parkes 64-metre radio telescope: This project aims to construct a state-of-the-art ultra-wide-band receiver and signal processing system for the Parkes 64-metre radio telescope. The receiver will operate across the entire 700 megahertz to four gigahertz band with outstanding sensitivity and polarimetric performance, providing a unique capability for high-time-resolution wide-bandwidth astronomy. It is expected to deliver enhanced science outcomes for a wide range of projects and greatly improve the telescope's operational efficiency, extending its lifetime into the Square Kilometre Array era. Key science projects include tests of theories of relativistic gravitation, including the search for gravitational waves, probing neutron star interiors and investigations of the magnetic structure of our galaxy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100107
Funder
Australian Research Council
Funding Amount
$672,000.00
Summary
The next generation fast radio burst detector for Australia. This project intends to provide a next-generation fast radio burst detector for the Australian Square Kilometre Array Pathfinder. The project expects to both transform our understanding of fast radio bursts, enigmatic flashes of radio waves of unknown origin, but also use the bursts as tools to study the cosmic web of matter that resides in intergalactic space. To do so, the project aims to deliver a more sensitive detection system ca ....The next generation fast radio burst detector for Australia. This project intends to provide a next-generation fast radio burst detector for the Australian Square Kilometre Array Pathfinder. The project expects to both transform our understanding of fast radio bursts, enigmatic flashes of radio waves of unknown origin, but also use the bursts as tools to study the cosmic web of matter that resides in intergalactic space. To do so, the project aims to deliver a more sensitive detection system capable of localising a large sample of fast radio bursts to greater distances, found commensal to other observations. This should provide significant benefit, including the resolutions to key open astrophysical questions and improved scientific outcomes for transient searches with the Square Kilometre Array.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989759
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting a ....Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries and will generate science to support and stimulate domestic industry, enhance the domestic knowledge base and international research profile, train students and future synchrotron scientists and foster domestic and international collaborations.Read moreRead less
ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the d ....ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the design of peptides and proteins for targeted scientific, agricultural, biotechnology, animal health and pharmaceutical applications. CIPPS will assemble leading researchers from diverse disciplines to create a sustainable national entity that will drive new Australian industries and train next generation researchers.Read moreRead less