Optimal control of nonlinear delay systems: theory, algorithms, and applications. Time delays are present in many engineering systems, including robots, irrigation canals, and chemical reactors. This project aims to develop state-of-the-art techniques for controlling systems with time delays in an optimal manner.
Relays and robustness: achieving optimal efficiency in wireless sensor networks. Wireless sensor networks consist of coordinated sensing and relay devices that offer us new ways to observe and interact with the physical world, with direct applications to national security and environmental monitoring. We aim to develop powerful new methods to get the best performance from a planned sensor network through smart relay deployment.
Optimal maintenance planning for critical mining and energy infrastructure. This project aims to develop cutting-edge mathematical algorithms for optimising maintenance activities in the mining and energy sectors. Such maintenance activities are prone to budget and time overruns due to poor planning - the result of outdated, inefficient manual processes. The project is expected to result in new maintenance planning methods, underpinned by rigorous mathematical theory, for reducing manual interve ....Optimal maintenance planning for critical mining and energy infrastructure. This project aims to develop cutting-edge mathematical algorithms for optimising maintenance activities in the mining and energy sectors. Such maintenance activities are prone to budget and time overruns due to poor planning - the result of outdated, inefficient manual processes. The project is expected to result in new maintenance planning methods, underpinned by rigorous mathematical theory, for reducing manual intervention and optimising both short- and long-term maintenance based on real-time sensor data. These new methods will be powerful tools for tackling the complexity of large-scale, time-critical maintenance projects, driving productivity in the resources industry and fostering collaboration between mathematicians and engineers.Read moreRead less
Maximisation of value in underground mine access design. This project represents a major advance in the problem of optimising the mine value associated with the access infrastructure of underground mines and providing powerful planning tools for management. The usefulness to the mining industry of the methods and algorithms the project is pioneering lies in their accuracy, flexibility and generality. Not only can they be used for benchmarking value in the design of specific mines, but they can ....Maximisation of value in underground mine access design. This project represents a major advance in the problem of optimising the mine value associated with the access infrastructure of underground mines and providing powerful planning tools for management. The usefulness to the mining industry of the methods and algorithms the project is pioneering lies in their accuracy, flexibility and generality. Not only can they be used for benchmarking value in the design of specific mines, but they can also determine the profitability or viability of mines under the use of new technologies. This is an important project for ensuring that Australia's mining industry remains efficient and internationally competitive. Given Australia’s economic dependence on mineral resources, it will also benefit the country as a whole.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100488
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Cellular dynamics of nanoengineered particles. Nanotechnology has the capacity to drive a new wave of biological innovation through engineering materials at the nanoscale. This project will advance understanding of how nanoengineered materials interact with biological systems to enable the development of nanomaterials for future translational research.
Data-Driven Multistage Robust Optimization—the New Frontier in Optimization. Robust optimisation is a powerful technology for decision-making in uncertain environments. Yet, developing numerically certifiable optimisation principles and data-driven methods that can be readily implemented by common computer algorithms remains an elusive goal for multistage robust optimisation. But it is crucial for the practical use of multistage optimisation. This project aims to develop this novel mathematical ....Data-Driven Multistage Robust Optimization—the New Frontier in Optimization. Robust optimisation is a powerful technology for decision-making in uncertain environments. Yet, developing numerically certifiable optimisation principles and data-driven methods that can be readily implemented by common computer algorithms remains an elusive goal for multistage robust optimisation. But it is crucial for the practical use of multistage optimisation. This project aims to develop this novel mathematical theory and methods by extending the investigators' recent award winning advances, including the von Neumann-prizewinning Lasserre-hierarchy approach. Results will provide a foundation and technologies for making superior decisions in the pervasive presence of big data uncertainty, enhancing data-driven innovation in AustraliaRead moreRead less
Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commerci ....Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commercial potential and important societal benefits.Read moreRead less
High-resolution elastography – Using optical micro-imaging of tissue mechanics to identify disease. Optical elastography, the probing of tissue’s micro-mechanical properties using optical imaging, offers new tools in surgery and pathology to improve differentiation of tissues. This project lays the groundwork for optical elastography to become a new medical micro-imaging modality by removing impediments to progress in this rapidly emerging field. On the micro-scale, between the scales of cells a ....High-resolution elastography – Using optical micro-imaging of tissue mechanics to identify disease. Optical elastography, the probing of tissue’s micro-mechanical properties using optical imaging, offers new tools in surgery and pathology to improve differentiation of tissues. This project lays the groundwork for optical elastography to become a new medical micro-imaging modality by removing impediments to progress in this rapidly emerging field. On the micro-scale, between the scales of cells and organs. This project will elucidate the origins of tissue mechanical contrast and determine limits on its measurement. It will develop a suite of probes: noncontact, endoscopic and needle, to enable access to all tissues in the body. To progress toward a new modality and inform our research, the project will test our tools on breast cancer tissues and burn scars.Read moreRead less
Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour ....Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour requirement, higher production rate and better quality control than conventional production methods. The new process will combine benefits from both supercritical fluid technology (green process) and microfluidics (high mass & heat transfer).Read moreRead less
Multi-modal virtual microscopy for quantitative diagnostic pathology. This project will contribute to the next generation of virtual microscopy systems that provide innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of diagnostic pathology. These tools will especially contribute to the screening and diagnosis of cervical, lung and bladder cancer.