Patterns Of Care And Quality Of Life In Patients With Pancreatic Cancer.
Funder
National Health and Medical Research Council
Funding Amount
$680,010.00
Summary
Available evidence suggests that care of patients with pancreatic cancer is variable and dependent on a variety of factors such as geographic location, socioeconomic status and hospital volume. Variability in care may influence survival and quality of life of patients. We propose to conduct a comprehensive study of the management of patients with pancreatic cancer in NSW and, in a substudy in QLD, to determine how variation in management affects patient quality of life.
Studies in cancer control. As life expectancy in Australia (and throughout the world) continues to rise, so will the burden of cancer escalate. Treating cancer after diagnosis is costly, and in many instances, unsuccessful. Preventive strategies promise to reduce the future cancer burden, yet our knowledge in this arena is limited by the lack of credible research as to what works and what does not. This application addresses this gap directly by conducting research into the control of two cancer ....Studies in cancer control. As life expectancy in Australia (and throughout the world) continues to rise, so will the burden of cancer escalate. Treating cancer after diagnosis is costly, and in many instances, unsuccessful. Preventive strategies promise to reduce the future cancer burden, yet our knowledge in this arena is limited by the lack of credible research as to what works and what does not. This application addresses this gap directly by conducting research into the control of two cancers which exact a growing toll in Australia and elsewhere. The work seeks to identify and understand the causal pathways to cancer, and then use this information to devise evidence-based strategies for cancer control.Read moreRead less
Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related dis ....Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related disease, and assess potential adverse outcomes of vaccination. Men are currently not covered by routine vaccination or screening programs; this research will assess the benefit to men of vaccinating women only, and will consider the impact of vaccination and other interventions targeted towards men.Read moreRead less
Work life after a diagnosis of breast, prostate and colorectal cancer: Major disruption or work as usual. Each year, over 40,000 working-age individuals (as well as their families and workplaces) are affected by a diagnosis of cancer. This novel and important study will, for the first time in Australia, identify the extent and effects of loss of skilled workers from the workforce because of a diagnosis of breast, prostate or colorectal cancer and will lead to the development of new interventions ....Work life after a diagnosis of breast, prostate and colorectal cancer: Major disruption or work as usual. Each year, over 40,000 working-age individuals (as well as their families and workplaces) are affected by a diagnosis of cancer. This novel and important study will, for the first time in Australia, identify the extent and effects of loss of skilled workers from the workforce because of a diagnosis of breast, prostate or colorectal cancer and will lead to the development of new interventions that help people to recover from cancer. This project is critical to help advance health and labour policies in Australia which currently faces an ageing population, global economic unrest and rising unemployment.Read moreRead less
Integration Of Epidemiological, Biological, And Health Services Data In Cancer Research
Funder
National Health and Medical Research Council
Funding Amount
$290,032.00
Summary
Improved understanding of carcinogenic mechanisms, such as the importance of gene and environment interaction, has placed increased emphasis on the need for studies combining biological and epidemiological data. The proposed research program incorporates a number of cross-disciplinary studies which bridge classical epidemiology and basic science and strive to improve the clinical relevance and translational potential of research outcomes.
Improving Cancer Outcomes In Under-studied Cancers By Understanding Their Risk Factors And Patterns Of Cancer Care.
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
Cancer is the second leading cause of disease burden in Australia. Much can be done to reduce this burden through effective cancer prevention and ensuring all patients receive optimal evidence-based care. This research focuses on thyroid, kidney and ovarian cancer and aims to increase knowledge of these cancers’ causes and to investigate variation in patient care and its impact on outcomes. Ultimately the objective of the work is to decrease Australia’s cancer burden.
Generating The Evidence To Control Cancer And Optimise Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$6,564,341.00
Summary
Our Program addresses the public health aspects of common cancers, particularly cancers of the skin and gynaecological tracts. Each year in Australia, nearly 400,000 people are treated for skin cancer, and more than 3,500 women develop ovarian or uterine cancer. Our aims are first, to understand how we might prevent these cancers in the future; second, to enhance diagnosis of these cancers; and third, to improve the survival and quality of life for people who are diagnosed with these cancers
Microsimulation Modelling Of Post-Polypectomy Colonoscopy Surveillance Strategies For The Prevention Of Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$101,535.00
Summary
This research will provide a comprehensive evidence-based framework for post-polypectomy endoscopic surveillance in bowel cancer screening. A population-based micro-simulation model of colorectal cancer development will be used to perform epidemiological and health economic evaluations of Australian and international endoscopic surveillance guidelines. These will help inform policy that will potentially lead to improvements in bowel cancer screening and surveillance programs in Australia.
Testing And Treatment For Prostate Cancer In Australia: Epidemiology And Modelling
Funder
National Health and Medical Research Council
Funding Amount
$267,886.00
Summary
We aim to use observational data and mathematical modelling to investigate testing and treatment for prostate cancer in Australia. We will incorporate changes in prostate-specific antigen (PSA) testing and in clinical practice to investigate: a) over-diagnosis, being cancer cases diagnosed through PSA testing that would not have been otherwise diagnosed; b) the effect of PSA testing on prostate cancer mortality; and c) mortality and health care use under different PSA test scenarios.
Quantifying Breast Cancer Over-diagnosis In An Organized Mammography Screening Program
Funder
National Health and Medical Research Council
Funding Amount
$92,314.00
Summary
While breast screening reduces breast cancer deaths by finding cancers earlier, it may also find cancers that would never have required treatment. Currently there is no clear consensus about the level over-diagnosis. This study will examine the extent of over-diagnosis by comparing the breast screening histories of women diagnosed with breast cancer and women who have not had breast cancer. Findings will inform policy on breast screening in Australia.