Methylation As A Risk And Prognostic Factor For Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$594,913.00
Summary
DNA methylation is a process playing critical roles throughout life by altering the expression of genes. This study aims to investigate the potential use of methylation as marker of risk and early diagnosis of breast cancer in women with no clinical evidence of disease and marker of prognosis and response to treatment in breast cancer cases.
A Genome-wide Association Study Of Endometrial Cancer
Funder
National Health and Medical Research Council
Funding Amount
$1,066,328.00
Summary
Endometrial cancer (uterine-womb cancer) is the most common invasive gynaecological cancer in Australia. Each year more than 1400 women are affected by the condition. The non-biased approach of our large study will identify genes that increase risk of this cancer, to provide information for future targeted therapies to prevent progression, and large-scale studies investigating how these genes interact with environmental factors such as hormone replacement therapy and obesity to cause disease.
Risk Factors For Upper Limb Fractures In Children Falling From Playground Equipment - A Case Control Study
Funder
National Health and Medical Research Council
Funding Amount
$355,770.00
Summary
Each year in Victoria, up to 5,000 children attend hospital emergency departments with injuries associated with playground equipment. Approximately 1,000 children are admitted to hospital, reflecting the severity of these injuries. The estimated total lifetime treatment costs of these injuries is in the vicinity of $7.9 million (1996-97). In over three quarters of these children, a fall from equipment resulted in injury. Arm fracture is the most frequent and most costly injury. This study aims t ....Each year in Victoria, up to 5,000 children attend hospital emergency departments with injuries associated with playground equipment. Approximately 1,000 children are admitted to hospital, reflecting the severity of these injuries. The estimated total lifetime treatment costs of these injuries is in the vicinity of $7.9 million (1996-97). In over three quarters of these children, a fall from equipment resulted in injury. Arm fracture is the most frequent and most costly injury. This study aims to determine the factors which influence the risk of arm fracture in the event of a fall from playground equipment. It will focus in particular, on the height of the equipment and the type of undersurfacing. The study will involve interviewing children who have fallen from playground equipment at school or at pre-school. The results of the study will be used to make recommendations on how to improve the safety of playgrounds.Read moreRead less