Controlling the organisation of matter using vortex fluidics. Vortex fluidic devices will be developed and used to construct functional complex molecules and materials, and probe the structure of self assembled systems. The scalable processing will be assessed for application in advanced materials production, the chemical industry and in developing complex molecules for drug discovery.
Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The exp ....Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The expected outcomes include new methods, models and a workable map of protein adsorption allowing us to 1) create advanced substrates for targeted applications and 2) understand existing phenomenon governed by naturally occurring nanoroughness. It will benefit manufacturing in fields ranging from biology to energy production.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100087
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-pro ....Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-property relationships, which are crucial for the development of the next generation of advanced materials with applications in electronics, optics, sensors, membranes, nanocoatings, biomaterials and polymer therapeutics. This facility underpins the efforts of the participating institutes in increasing the quality and quantity of research outcomes.Read moreRead less
The rational design and construction of new genetic circuits for applications in synthetic biology. By designing, building and testing new gene control modules, this project will gain an understanding of the design principles required for the construction of biological circuits with predictable and controllable behaviour. The ability to build such circuits will have significant economic benefit in areas such as metabolic engineering and biomedicine.
Discovery Early Career Researcher Award - Grant ID: DE120101788
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Shape sorting of nanoparticles at oil-water interfaces in microchannels. This project aims to study the effect of shape on the adsorption of nanoparticles at an oil/water interface and develop a rapid, inexpensive, efficient, versatile method for shape sorting of nanoparticles using a microfluidic approach. This technique can be applied for fractionation of synthetic nanoparticles, biosample analysis and environmental monitoring.
An account of wetting phenomena on nano-engineered surfaces. This project aims to provide researchers and industry with a toolbox to predict wetting behaviour on surfaces with nanoscale topography. A combined experimental and numerical study will lead to the discovery of the mechanisms by which topographical and chemical properties of the surface trigger the formation of nanostructure-induced air pockets and how these phenomena determine surface wettability. This will provide significant benefi ....An account of wetting phenomena on nano-engineered surfaces. This project aims to provide researchers and industry with a toolbox to predict wetting behaviour on surfaces with nanoscale topography. A combined experimental and numerical study will lead to the discovery of the mechanisms by which topographical and chemical properties of the surface trigger the formation of nanostructure-induced air pockets and how these phenomena determine surface wettability. This will provide significant benefits, as the predictive surface-wettability model will enhance controllability and productivity of diverse manufacturing processes and lead to new applications, high-value products and economic benefits in mining, energy, electronics, biomedicine and other fields.Read moreRead less
Rational design of genetic circuits that respond to transient signals. Engineered genetic circuits with predictable and robust behaviour promise unprecedented environmental and economic benefits. Yet much work remains to be done before living devices can routinely be built from a standarised set of biological parts - the goal of synthetic biologists. By studying how natural genetic switch circuits respond to transient signals, this project aims to uncover a set of design rules which could be use ....Rational design of genetic circuits that respond to transient signals. Engineered genetic circuits with predictable and robust behaviour promise unprecedented environmental and economic benefits. Yet much work remains to be done before living devices can routinely be built from a standarised set of biological parts - the goal of synthetic biologists. By studying how natural genetic switch circuits respond to transient signals, this project aims to uncover a set of design rules which could be used to construct and control purpose-built genetic networks and pathways. The results of this project are expected to add to the molecular tookit available to synthetic biologists.Read moreRead less
Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk ass ....Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk assessment. This is intended to be achieved by developing and validating high-throughput in vitro toxicity screening platforms for manufactured nanoparticles. The approach is based on advanced lab-on-a-chip microfluidic technologies. The predictive power of the platform will be refined and optimised via ex-vivo and in-vivo models.Read moreRead less
Controlling nano-carbon complexity and function. The project aims to develop versatile continuous flow thin film microfluidic device technology incorporating different external fields, including innovative magnetic or electric fields coupled with pulsed lasers, for gaining access to novel nano-carbon material for which current methods are ineffective or of limited utility. The technology will allow exquisite control, with real time monitoring, on reforming of carbon into functional material with ....Controlling nano-carbon complexity and function. The project aims to develop versatile continuous flow thin film microfluidic device technology incorporating different external fields, including innovative magnetic or electric fields coupled with pulsed lasers, for gaining access to novel nano-carbon material for which current methods are ineffective or of limited utility. The technology will allow exquisite control, with real time monitoring, on reforming of carbon into functional material with tunable properties, along with the self assembly of nano-carbon, and fabricating composites of nano-carbon material. Understanding their fundamental properties including photoluminescence will be targeted, for leveraging the properties in applications to generate new processes and products.
Read moreRead less
Structural diverse nanocarbon using continuous flow thin film microfluidics. This project aims to develop continuous flow thin film microfluidic device technology to gain access to nano-carbon material or carbon nano-material. This project will exploit high shear stress in dynamic thin films, field effects, including Faraday waves, plasma, magnetic, laser and LED irradiation. The technology is expected to allow both scalable ‘top down’ synthesis of graphene scrolls, laterally slicing carbon nano ....Structural diverse nanocarbon using continuous flow thin film microfluidics. This project aims to develop continuous flow thin film microfluidic device technology to gain access to nano-carbon material or carbon nano-material. This project will exploit high shear stress in dynamic thin films, field effects, including Faraday waves, plasma, magnetic, laser and LED irradiation. The technology is expected to allow both scalable ‘top down’ synthesis of graphene scrolls, laterally slicing carbon nanotubes and composites of different types of carbon, and ‘bottom up’ synthesis of nano-carbon from natural saccharides. By incorporating sustainability metrics including scalability, renewable feed-stocks and minimising waste, this research is expected to be attractive to industry and minimise the effect on the environment.Read moreRead less