Metal injection moulding of aluminium. The aim of this project is to develop a metal injection moulding (MIM) system for aluminium by employing point defect engineering to enhance the solid state sintering of aluminium. This study will also incorporate an econometric analysis of the potential for specific aluminium MIM parts. Using this novel, multidisciplinary approach, the market definition and the technology development will occur concurrently. The outcome will be an aluminium MIM system and ....Metal injection moulding of aluminium. The aim of this project is to develop a metal injection moulding (MIM) system for aluminium by employing point defect engineering to enhance the solid state sintering of aluminium. This study will also incorporate an econometric analysis of the potential for specific aluminium MIM parts. Using this novel, multidisciplinary approach, the market definition and the technology development will occur concurrently. The outcome will be an aluminium MIM system and a new business opportunity for a Queensland manufacturing company in a market that is growing at 10-25% per year and is expected to exceed $US1 billion in 2003.Read moreRead less
Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessmen ....Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessment of the distributional impact of a wide range of possible reforms, including how the outcomes of any policy change will affect disadvantaged sections of our society, whether different generations will be fairly treated, and the impact by gender.Read moreRead less
Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant be ....Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant benefits such as the development of new econometric theory, advanced computational methods and evidence-based guidelines for policymakers.Read moreRead less
Investigating the Concordance and Transmission of International Business Cycles. Business cycle recessions are costly. Apart from the economic cost, there is the devastating social and psychological impact of unemployment on individuals and families. The 1990/91 recession cost Australia somewhere between $25 and $30 billion in lost output and resulted in a half a million additional unemployed. Australia will certainly experience another recession and, given its openness to international influenc ....Investigating the Concordance and Transmission of International Business Cycles. Business cycle recessions are costly. Apart from the economic cost, there is the devastating social and psychological impact of unemployment on individuals and families. The 1990/91 recession cost Australia somewhere between $25 and $30 billion in lost output and resulted in a half a million additional unemployed. Australia will certainly experience another recession and, given its openness to international influences, it is likely that it will originate elsewhere in the world. In delivering a greater understanding of the interdependencies in international business cycles, the project will assist economic policymakers in their efforts to ameliorate Australia's next recession. Read moreRead less
A humanised sensory neuron high-throughput screening platform . Sensory neurons are responsible for converting external stimuli such as touch or temperature into graded electrical signals that allow us to interact with the world around us. However, unlike other cell types, sensory neurons cannot proliferate and thus must be removed from human cadavers, or animals, in order to study their pharmacology and function. This limits our ability to understand neuronal signalling pathways. This project a ....A humanised sensory neuron high-throughput screening platform . Sensory neurons are responsible for converting external stimuli such as touch or temperature into graded electrical signals that allow us to interact with the world around us. However, unlike other cell types, sensory neurons cannot proliferate and thus must be removed from human cadavers, or animals, in order to study their pharmacology and function. This limits our ability to understand neuronal signalling pathways. This project aims to use sensory neurons derived from human stem cells to develop and optimise assays that can be used to study the pharmacology and function of human sensory neurons in vitro. This enhances access to critical model systems and technology platforms and removes the need for isolation of cells from cadavers. Read moreRead less
Development of New Generation Magnetic Circular Dichroism Spectrometers. We are building two Magnetic Circular Dichroism (MCD spectrometers) to meet a rising need in the study of metallo-proteins and other molecules of biological interest. The PhD project described in this application will involve instrumentation design, interfacing and sampling handling development for biological samples. We wish to involve a Lastek, a scientific instrumentation company, in the possible commercial development o ....Development of New Generation Magnetic Circular Dichroism Spectrometers. We are building two Magnetic Circular Dichroism (MCD spectrometers) to meet a rising need in the study of metallo-proteins and other molecules of biological interest. The PhD project described in this application will involve instrumentation design, interfacing and sampling handling development for biological samples. We wish to involve a Lastek, a scientific instrumentation company, in the possible commercial development of aspects of this project.Read moreRead less
Redirecting Carbon Flow through Mesophyll and Bundle Sheath Cells of Sugarcane to Produce Poly-3-Hydroxybutyrate. This project is part of the National Priorities "Frontier Technologies for Building and Transforming Australian Industries." Using innovative plant metabolic engineering technologies combined with sophisticated computer modeling we are generating green plants that produce renewable, biodegradable, bioplastics possessing properties such that they are suitable replacements for petrol ....Redirecting Carbon Flow through Mesophyll and Bundle Sheath Cells of Sugarcane to Produce Poly-3-Hydroxybutyrate. This project is part of the National Priorities "Frontier Technologies for Building and Transforming Australian Industries." Using innovative plant metabolic engineering technologies combined with sophisticated computer modeling we are generating green plants that produce renewable, biodegradable, bioplastics possessing properties such that they are suitable replacements for petroleum-derived products in many applications. During the course of these studies, we are increasing our basic level of understanding of plant metabolism of important bioenergy crops. The production of renewable, bioplastics in sugarcane will help to diversify the Australian sugarcane industry by providing a value-added product with significant world-wide markets.Read moreRead less
Red Cell Polymorphisms and Malaria. Certain red blood cell disorders have been associated with innate protection against malaria infection. However many early studies were inconclusive. We intend to carry out a comprehensive study to investigate the effect of red blood cell differences on the invasion and/or growth of Plasmodium falciparum in vitro using improved techniques. Identification of red cell components involved in interaction with P.falciparum would give a better understanding of host ....Red Cell Polymorphisms and Malaria. Certain red blood cell disorders have been associated with innate protection against malaria infection. However many early studies were inconclusive. We intend to carry out a comprehensive study to investigate the effect of red blood cell differences on the invasion and/or growth of Plasmodium falciparum in vitro using improved techniques. Identification of red cell components involved in interaction with P.falciparum would give a better understanding of host parasite interactions which may in turn suggest novel approaches or pathways to persue. This may eventually lead to the development of novel therapeutics.
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A lipodomic approach to cnidarian-dinoflagellate symbiosis. Fatty Acids are essential for human health and for reef health. This lipodomic study using newly developed techniques, aims to understand the essential and non-essential fatty acid metabolic exchange in the symbiosis that drives coral reef formation and health, and in turn gives reflective insight into our own metabolism.
Assessing the impacts of proposed carbon trading and tax schemes on the Australian electricity industry and the overall economy. Currently, policymakers require a much clearer understanding of the impacts of different carbon abatement policies. Mounting evidence on global warming is making this an increasingly urgent priority. The proposed project is specifically concerned with using state of the art economic modelling approaches to give the best advice possible to policymakers in crafting an e ....Assessing the impacts of proposed carbon trading and tax schemes on the Australian electricity industry and the overall economy. Currently, policymakers require a much clearer understanding of the impacts of different carbon abatement policies. Mounting evidence on global warming is making this an increasingly urgent priority. The proposed project is specifically concerned with using state of the art economic modelling approaches to give the best advice possible to policymakers in crafting an environmentally sustainable set of economic policy instruments that can maintain our enviable standard of living well into the future. The findings of the project will be available before the new Kyoto negotiation round commences.Read moreRead less