Tracking the musculoskeletal health and performance of talented adolescent female athletes. The vision is to gain an innovative understanding of risk factors for the early detection or prevention of injury, and to identify factors that promote participation longevity in young athletes. The biomechanics explored in this study will provide a basis for larger studies in future years. Large economic and social benefits can be gained from increased knowledge of injury prevention early in life. Lowere ....Tracking the musculoskeletal health and performance of talented adolescent female athletes. The vision is to gain an innovative understanding of risk factors for the early detection or prevention of injury, and to identify factors that promote participation longevity in young athletes. The biomechanics explored in this study will provide a basis for larger studies in future years. Large economic and social benefits can be gained from increased knowledge of injury prevention early in life. Lowered injury costs provide immediate cost benefits to the nation. Ultimately, in a nation familiar with the high costs of cardiovascular and musculoskeletal diseases, the health sector of Australia will be the greatest benefactor of this project.Read moreRead less
Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and aga ....Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and again make Australian TID the international benchmark. Results will highlight the role of TID practices in improving recreational participation and maximising, attracting, developing and retaining sport talent. This will result in improved use of sports limited TID funding by providing greater understanding of factors that influence elite selection and sport development.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100020
Funder
Australian Research Council
Funding Amount
$3,998,796.00
Summary
ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simula ....ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simulation system and robot simulators for surgical training and medical device assessment, and post-surgical assessment tools. The outcomes of the centre will significantly contribute to Australia by improved health outcomes, economic benefits, and a skilled workforce able to advance this joint biomechanics fields.Read moreRead less
Children Walking Well. Healthy feet in childhood are the foundation for musculoskeletal health and mobility throughout life. However, little is known about the effect of shoes worn on children. This Australian project is the first to address this shortcoming. A multidisciplinary team will investigate: factors contributing to consumer decision-making; footwear usage and selection; and the relationship between footwear styles, anatomical profile, biomechanics and physical activity. From our id ....Children Walking Well. Healthy feet in childhood are the foundation for musculoskeletal health and mobility throughout life. However, little is known about the effect of shoes worn on children. This Australian project is the first to address this shortcoming. A multidisciplinary team will investigate: factors contributing to consumer decision-making; footwear usage and selection; and the relationship between footwear styles, anatomical profile, biomechanics and physical activity. From our identification of mismatches between evidence of the relationship between shoes and function and current stakeholder knowledge and decision-making, we will make recommendations for how shoe manufacturers and health professionals can promote healthy feet in children.Read moreRead less
The implications of resistance training for the control of movement. Resistance training (or weight lifting) is an essential element of comprehensive rehabilitation programs in a wide range of clinical settings. However, because we know little about how the organization of the nervous system is affected by training with high loads, the consequences of resistance training for our ability to control functional movements are unclear. The ultimate goal of this research is to generate basic knowledge ....The implications of resistance training for the control of movement. Resistance training (or weight lifting) is an essential element of comprehensive rehabilitation programs in a wide range of clinical settings. However, because we know little about how the organization of the nervous system is affected by training with high loads, the consequences of resistance training for our ability to control functional movements are unclear. The ultimate goal of this research is to generate basic knowledge about the impact of resistance training on nervous system function. The research will lead to the design of injury prevention and rehabilitation programs that are maximally effective, and provide a genuine benefit to the community.Read moreRead less
Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spri ....Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spring-like function of the foot. It will explain a conceptually novel design allowing shoes to support our feet, whilst harnessing the energetic benefits of the foot's spring-like function. This research has the potential to revolutionise athletic footwear design and has direct implications for enhanced performance in running athletes.Read moreRead less
Understanding the potency and role of individual stem cells in the skin using Rainbow technology. To renew itself, the skin and its components rely on the activity of stem cells. This project will define more precisely the role of each individual stem cell by labelling them with a unique colour and following its fate. This project has the potential to change our current view on how the skin maintains and repairs itself.
Migration-Dependent Signalling in Macrophages . The project aims to investigate a mechanism of communication used by immune cells to guide each other towards sites of damage. The project will characterise newly revealed cell signalling membrane trails left behind by migrating cells, utilising biochemistry, innovative imaging and microscopy and a transparent zebrafish model to view cell migration through living tissues. Expected outcomes include new fundamental knowledge in the area of immune cel ....Migration-Dependent Signalling in Macrophages . The project aims to investigate a mechanism of communication used by immune cells to guide each other towards sites of damage. The project will characterise newly revealed cell signalling membrane trails left behind by migrating cells, utilising biochemistry, innovative imaging and microscopy and a transparent zebrafish model to view cell migration through living tissues. Expected outcomes include new fundamental knowledge in the area of immune cell migration with relevance to the basic biology of inflammation, repair and regeneration and new innovations for cell imaging. Significant benefits are expected to arise from this new knowledge and from advanced skills training and improved national capabilities in bio-imaging and analysis.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347607
Funder
Australian Research Council
Funding Amount
$306,000.00
Summary
FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged ex ....FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged expertise as well as priority within their respective institutions. In addition, it will facilitate wide-ranging collaborative arrangements to further develop and exploit this research area.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561041
Funder
Australian Research Council
Funding Amount
$347,358.00
Summary
A New Generation Biosensor and Fluorescence Facility for Proteomics. The complete DNA sequence (the genome) is now known for many organisms and advances are being made to identify the complement of messenger RNA (the transcriptome) and the resultant collection of proteins (the proteome). The genome is largely fixed while the transcriptome and proteome differ between cell types in an organism and constantly vary to adapt the cell to changing conditions. The mediators of these variations are prote ....A New Generation Biosensor and Fluorescence Facility for Proteomics. The complete DNA sequence (the genome) is now known for many organisms and advances are being made to identify the complement of messenger RNA (the transcriptome) and the resultant collection of proteins (the proteome). The genome is largely fixed while the transcriptome and proteome differ between cell types in an organism and constantly vary to adapt the cell to changing conditions. The mediators of these variations are proteins, interacting with each other and with signal molecules. The next frontier in molecular biology is to identify and quantify these protein interactions. Our two institutions have a very large cohort of biologists whose research on proteins would be greatly facilitated by the Biacore 3000 and the ISS K2.Read moreRead less