Characterisation and Treatment of Reverse Osmosis Concentrates from Water Recycling Applications. Concentrates from reverse osmosis (RO) pose a considerable threat to both the environment but also the successful implementation of reverse osmosis as a technology. Naturally, the concentrate contains everything that the RO retains and hence contaminants such as viruses, organics such as pharmaceutically active compounds and hormones as well as nutrients and salinity. Treatment of such waste streams ....Characterisation and Treatment of Reverse Osmosis Concentrates from Water Recycling Applications. Concentrates from reverse osmosis (RO) pose a considerable threat to both the environment but also the successful implementation of reverse osmosis as a technology. Naturally, the concentrate contains everything that the RO retains and hence contaminants such as viruses, organics such as pharmaceutically active compounds and hormones as well as nutrients and salinity. Treatment of such waste streams will enhance the health of receiving water bodies and reduce the risk of increased build up of contaminants if wastes are recycled into wastewater treatment plants. New ways to treat such contaminants will be explored, the efficiency and cost evaluated in the broader water cycle and sustainability framework.Read moreRead less
Mitigation of silica nanoparticle scaling in water treatment. This project aims to develop strategies to mitigate silica scaling at coal seam gas (CSG) water treatment facilities. CSG is adsorbed to the surface of coal along fractures and cleats and released when pressure is reduced by removal of groundwater, which has chemistry specific to the region from which it is extracted. Desalination of produced water is severely impacted by mineral scaling on reverse osmosis membranes. This project will ....Mitigation of silica nanoparticle scaling in water treatment. This project aims to develop strategies to mitigate silica scaling at coal seam gas (CSG) water treatment facilities. CSG is adsorbed to the surface of coal along fractures and cleats and released when pressure is reduced by removal of groundwater, which has chemistry specific to the region from which it is extracted. Desalination of produced water is severely impacted by mineral scaling on reverse osmosis membranes. This project will consider silica and silica-rich nanoparticles in concert with cations and organics, with the aim of better managing cations so to facilitate nanoparticle lubrication. Project outcomes may include more productive use of assets, improved pre-treatment infrastructure to support reverse osmosis operation, and the environmental benefits of reduced chemical waste and increased water recovery.Read moreRead less
Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the ....Optimising dissolved air flotation (DAF) for algae removal by bubble modification in drinking water and advanced wastewater systems. Algal blooms in potable water reservoirs and advanced wastewater treatment lagoons can impact the performance and economic viability of water treatment processes resulting in taste and odour episodes and the risk of algal toxins as well as causing further limitation to already stressed water resources in Australia. This project aims to develop an adaptation of the dissolved air flotation process that is already used for algae treatment that will provide a more robust, economic and sustainable barrier to algal cells in accordance with the Australian Drinking and Recycled Water Guidelines.Read moreRead less
Assessment and optimisation of N-nitrosamine rejection by reverse osmosis for planned potable water recycling applications. Water recycling is a strategic approach to secure potable water supplies in Australia. The underlying challenge is to protect public health by ensuring robust treatment processes capable of effectively eliminating contaminants of concern. This research aims to enhance the capabilities of advanced water treatment plant designers and operators to control N-nitrosamine concent ....Assessment and optimisation of N-nitrosamine rejection by reverse osmosis for planned potable water recycling applications. Water recycling is a strategic approach to secure potable water supplies in Australia. The underlying challenge is to protect public health by ensuring robust treatment processes capable of effectively eliminating contaminants of concern. This research aims to enhance the capabilities of advanced water treatment plant designers and operators to control N-nitrosamine concentrations by optimised reverse osmosis treatment. A predictive model will be developed allowing for the optimisation of N-nitrosamine removal by reverse osmosis filtration in full scale installation. The project will directly enhance the viability of indirect potable water recycling and thus reduce dependency on water sources vulnerable to climate change.Read moreRead less
Membrane distillation development for concentrated solar thermal systems. Membrane distillation development for concentrated solar thermal systems. This project aims to develop a new membrane distillation module that works with a high efficiency solar thermal tower system. Fresh water and energy are inextricably linked and form the basis for all human activity. Remote locations in Australia and the Middle East and North Africa are blessed with abundant solar resources and increasing levels of de ....Membrane distillation development for concentrated solar thermal systems. Membrane distillation development for concentrated solar thermal systems. This project aims to develop a new membrane distillation module that works with a high efficiency solar thermal tower system. Fresh water and energy are inextricably linked and form the basis for all human activity. Remote locations in Australia and the Middle East and North Africa are blessed with abundant solar resources and increasing levels of development, but burdened by access to reliable water treatment and electricity generation facilities. This project will use recently developed materials and design tools to overcome technical challenges that limited membrane distillation technology. This is expected to open up an innovative method for co-production of water and electricity which can handle transient solar and water quality inputs.Read moreRead less
Identification of novel biomarkers in tears for prostate cancer diagnosis and prognosis. The purpose of this study is to identify novel biomarkers in the tears of patients with CaP. The use of the several techniques will increase the chance of success and enable us to find more diagnostic markers. If successful, the identified proteins may be used to diagnose and determine the stage of cancer. This will help guide clinicians in choosing the best treatment methods for an individual patient. The m ....Identification of novel biomarkers in tears for prostate cancer diagnosis and prognosis. The purpose of this study is to identify novel biomarkers in the tears of patients with CaP. The use of the several techniques will increase the chance of success and enable us to find more diagnostic markers. If successful, the identified proteins may be used to diagnose and determine the stage of cancer. This will help guide clinicians in choosing the best treatment methods for an individual patient. The markers may also be used to monitor the disease progress and the effects of treatment. The results from this study may improve the prognosis of CaP patients.Read moreRead less
Development of a non-invasive diagnostic test of Embryo Viability. A successful outcome will:
. improve the cost effectiveness of assisted reproductive technologies resulting in reduced health care costs and allowing greater use of ART in animal production
. by greater cost-effectiveness, facilitate greater access to these advanced technologies in less well developed economies
. build the national capacity in development and validation of biotech diagnostics
. build collaborative relationsh ....Development of a non-invasive diagnostic test of Embryo Viability. A successful outcome will:
. improve the cost effectiveness of assisted reproductive technologies resulting in reduced health care costs and allowing greater use of ART in animal production
. by greater cost-effectiveness, facilitate greater access to these advanced technologies in less well developed economies
. build the national capacity in development and validation of biotech diagnostics
. build collaborative relationship between the CI, University of Sydney and a leading industry partner (Cook Australia)
. lead to significant new fundamental knowledge in embryology that will be of major International significance
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Single molecule spectroscopy-guided design of thermostable industrial enzymes. The production and engineering of proteins are key methodologies in life sciences. The current project aims to develop new approaches to accelerate the production and analysis of proteins and to apply them to discover improved proteins for use as feedstock supplements.
Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative ....Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative that could be incorporated into DTA programs if their ecological relevance can be demonstrated. This project will develop and validate a new and internationally significant suite of in vitro bioassays for incorporation into DTA programs, leading to more ethical, cost effective and improved environmental protection.Read moreRead less
Engineering cyanobacteria for high-value flavours and fragrances production. Engineering the metabolism of cyanobacteria for industrial production of flavours and fragrances has great commercial potential. Cyanobacteria capture more than 25% of the planet’s carbon. Due to their native metabolism and capacity to express complex plant proteins, they represent an attractive Synthetic Biology platform for the biosynthesis of flavours and fragrances. Combining physiological strain characterisation an ....Engineering cyanobacteria for high-value flavours and fragrances production. Engineering the metabolism of cyanobacteria for industrial production of flavours and fragrances has great commercial potential. Cyanobacteria capture more than 25% of the planet’s carbon. Due to their native metabolism and capacity to express complex plant proteins, they represent an attractive Synthetic Biology platform for the biosynthesis of flavours and fragrances. Combining physiological strain characterisation and ‘omics studies, new Synthetic Biology strategies and models will be developed. The project aims at engineering a suite of modified freshwater and marine cyanobacteria for flavours and fragrances biosynthesis. The project aims at enabling solar biomanufacturing to underpin the emergence of an advanced Australian bioeconomy.Read moreRead less