Flotation separation of nanoparticles. This project deals with the separation of fine nanoparticles suspended in water, by attachment to small gas bubbles. It aims to find a way of removing nanoparticles from water, or of separating one species from another. The process could be used for simple solids such as metal oxides, and for biological materials such as large molecules, viruses and small bacteria. The work will be both theoretical and experimental. This ground-breaking project will build u ....Flotation separation of nanoparticles. This project deals with the separation of fine nanoparticles suspended in water, by attachment to small gas bubbles. It aims to find a way of removing nanoparticles from water, or of separating one species from another. The process could be used for simple solids such as metal oxides, and for biological materials such as large molecules, viruses and small bacteria. The work will be both theoretical and experimental. This ground-breaking project will build upon past successes of the applicant, whose invention in the field of resource recovery is contributing close to $1 billion a year to Australia's exports.Read moreRead less
Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials fo ....Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials for widespread environmental, agricultural and food applications.Read moreRead less
Optimising Fouling Control in Membrane Bioreactors. Membrane bioreactors (MBR) are growing in importance for wastewater treatment because they offer an alternative for producing higher effluent quality wastewater within a more compact space compared to conventional processes. However, due to the pumping and bubbling used to keep the membranes clear of foulants resulting from the biological processes in MBR's, controlling fouling incurs significant energy usage and costs. The proposal aims to red ....Optimising Fouling Control in Membrane Bioreactors. Membrane bioreactors (MBR) are growing in importance for wastewater treatment because they offer an alternative for producing higher effluent quality wastewater within a more compact space compared to conventional processes. However, due to the pumping and bubbling used to keep the membranes clear of foulants resulting from the biological processes in MBR's, controlling fouling incurs significant energy usage and costs. The proposal aims to reduce the costs of fouling control by understanding the optimal conditions to remove these depositions and improve the design of MBR modules, operating conditions and shear delivery in the membrane system.Read moreRead less
Macromolecular Fouling in Membrane Bioreactors. As the demands for domestic and industrial water increasing in Australia and overseas, membrane bioreactors (MBR) offer an alternative for producing higher effluent quality wastewater compared to conventional processes. However, aeration costs used to remove fouling deposits (which reduce the operating performance) need to be further minimised. The proposal aims to study fundamental mechanisms involve in the deposition of foulant components by usin ....Macromolecular Fouling in Membrane Bioreactors. As the demands for domestic and industrial water increasing in Australia and overseas, membrane bioreactors (MBR) offer an alternative for producing higher effluent quality wastewater compared to conventional processes. However, aeration costs used to remove fouling deposits (which reduce the operating performance) need to be further minimised. The proposal aims to study fundamental mechanisms involve in the deposition of foulant components by using model systems of polysaccharides, proteins and microbial cells and comparing these with real MBR systems. The effect of bubbling varied gas compositions (air/H2S ratios) a novel approach in this study will be investigated to prevent or remove foulants in MBR systems. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882388
Funder
Australian Research Council
Funding Amount
$130,000.00
Summary
Advanced characterisation of organics and biopolymers in water and wastewater treatment. Although membrane technology is increasingly used for water production, wastewater treatment and reclamation, fouling by complex bio-organics is a major limitation. The liquid chromatography-organic carbon detection and the Flow FFF equipments give detailed analyses of the complex organics, thereby helping to understand the fouling and organic removal mechanisms allowing process optimisation. The availabilit ....Advanced characterisation of organics and biopolymers in water and wastewater treatment. Although membrane technology is increasingly used for water production, wastewater treatment and reclamation, fouling by complex bio-organics is a major limitation. The liquid chromatography-organic carbon detection and the Flow FFF equipments give detailed analyses of the complex organics, thereby helping to understand the fouling and organic removal mechanisms allowing process optimisation. The availability of these equipments will ramatically improve the quality of a number of research projects currently funded and being developed in Australia. This equipment would provide necessary infrastructure to keep Australian researchers world leaders in this research field (one of Australian top research priorities) and attract national and international collaborations.Read moreRead less
Pancreatic Differentiation of Cord Blood Stem Cells using Smart Surfaces. Cord blood cells obtained at the time of delivery of a baby are a valuable resource that have the potential to develop into many cell types. This Project entails attaching stem cells derived from cord blood to appropriate 3 dimensional smart surfaces, and examining the ability of such cells to develop into insulin-producing cells. An understanding of how to coax stem cells, seeded on to smart surfaces, to develop into ma ....Pancreatic Differentiation of Cord Blood Stem Cells using Smart Surfaces. Cord blood cells obtained at the time of delivery of a baby are a valuable resource that have the potential to develop into many cell types. This Project entails attaching stem cells derived from cord blood to appropriate 3 dimensional smart surfaces, and examining the ability of such cells to develop into insulin-producing cells. An understanding of how to coax stem cells, seeded on to smart surfaces, to develop into mature cells with different functions will enhance our ability to understand how cells develop. As well, it enhance the potential usefulness of cord blood for research purposes. Read moreRead less
Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types o ....Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types of tissues being generated for clinical applications, including possible applications in the treatment of heart disease, the largest killer of people in the Western world. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100125
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and inter ....Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and international research collaborations, develop cutting-edge technology and unique local skills, and contribute to Australia maintaining a leading position in redox-related research in biology and medicine. In doing so, the facility will increase the likelihood of gaining future, value-adding funding.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237427
Funder
Australian Research Council
Funding Amount
$269,000.00
Summary
Equipment for Fluorescence-Based Cellular Analysis. The requested equipment is needed by a large grouping of highly productive researchers to carry out work across a very broad range of fields that is otherwise difficult or impossible to perform. The new equipment will facilitate obtaining many exciting and important outcomes, including identification of: (i) mechanisms controlling cell death, (ii) natural biological products that may have commercial applications (eg anti-fouling agents), (iii) ....Equipment for Fluorescence-Based Cellular Analysis. The requested equipment is needed by a large grouping of highly productive researchers to carry out work across a very broad range of fields that is otherwise difficult or impossible to perform. The new equipment will facilitate obtaining many exciting and important outcomes, including identification of: (i) mechanisms controlling cell death, (ii) natural biological products that may have commercial applications (eg anti-fouling agents), (iii) "probiotic" bacteria and vaccines that may be used to protect animals from disease, and (iv) mechanisms by which changes in human lens proteins contribute to the development of cataract.Read moreRead less
New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R& ....New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R&D company that will lead to development of new techniques for use in biotechnology in Australia and overseas.Read moreRead less