Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989226
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Multi-photon imaging for infection, immunity, and self recognition. This proposal will address a gap in our imaging capabilities, allowing us to visualise the movement of immune cells and infectious agents such as bacteria and viruses within living tissues. This will immensely improve our capacity to understand interactions between the immune system, invading organisms and the rest of our body. The intravital imaging system will provide novel insights into how the immune system works, which will ....Multi-photon imaging for infection, immunity, and self recognition. This proposal will address a gap in our imaging capabilities, allowing us to visualise the movement of immune cells and infectious agents such as bacteria and viruses within living tissues. This will immensely improve our capacity to understand interactions between the immune system, invading organisms and the rest of our body. The intravital imaging system will provide novel insights into how the immune system works, which will benefit the design of vaccines, the treatment of cancer, and our understanding of allergy. This state-of-the-art facility will also provide vital training in an emerging technology that will have application in many areas of biology.
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Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561229
Funder
Australian Research Council
Funding Amount
$518,427.00
Summary
Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at V ....Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at Victoria University for the development of communication and endoscopic technology. The instrument design will allow multiple use of the lightsource and choice of specific imaging devices (microscopes) to ensure that applications in biocellular imaging, intravital microscopy and fiber optic design and imaging are individually optimised.Read moreRead less