Shaken Baby Syndrome: Characterization Of A Model And Evaluation Of Novel Pharmacological Therapies
Funder
National Health and Medical Research Council
Funding Amount
$412,460.00
Summary
Shaken baby syndrome is a form of traumatic brain injury in infants less than 2 years of age. It results in death in 10-40 % of cases, and neurological problems in survivors. No treatment exists largely because there is no well characterized model of the syndrome that replicates the human situation. This study will fully characterize our newly developed model of shaken baby syndrome and examine the effectiveness of a novel interventional strategy targeting brain swelling.
MOSAIC: A GP Cluster Randomised Trial To Reduce Partner Violence Among Pregnant Women And Women With Pre-school Children
Funder
National Health and Medical Research Council
Funding Amount
$432,250.00
Summary
Intimate partner abuse or domestic violence is common and damaging for women in the early childbearing years. It has a negative effect on the mental and physical health of women and their children. Because of poor health, victimised women and children are frequent attenders to family doctors (GPs), but doctors face many barriers in making an effective response. One of these barriers is the critical absence of evidence for what would help women attending GPs in dealing with partner abuse. This is ....Intimate partner abuse or domestic violence is common and damaging for women in the early childbearing years. It has a negative effect on the mental and physical health of women and their children. Because of poor health, victimised women and children are frequent attenders to family doctors (GPs), but doctors face many barriers in making an effective response. One of these barriers is the critical absence of evidence for what would help women attending GPs in dealing with partner abuse. This is vital to inform both GP training and clinical practice. There is sound evidence that home visiting or support by peers improves the health of disadvantaged mothers and children. Similarly, advocacy improves the health and wellbeing of abused women. The MOSAIC community intervention trial combines these two elements: home visiting-peer support and domestic violence advocacy and this strategy will be evaluated in a randomised trial. The trial aims to reduce partner abuse and depression among women pregnant or with children under 5 attending GPs. It also aims to strengthen mother-child bonds. Trained and supported GPs from 40 participating practices will identify 700 abused or at risk women over a 40 week period. Women in the intervention arm of the trial, identified as abused or at risk by their GPs will be offered the support of trained para-professional 'mentor mothers' for up to a year, while the comparison arm will be offered standard GP care. Recent funding allows a pilot study of mentor mother recruitment and training to be undertaken in 2003. The study will strengthen GP support for this difficult issue and build a 'critical mass' of GPs interested in partner abuse management in the 5 participating divisions. The MOSAIC study will assess the value to GPs and women of an enhanced support system for victims' care and provide much needed evidence of an intervention embedded in general practice to reduce partner abuse of pregnant women and women with young children.Read moreRead less
Can parents teach their children to drink alcohol responsibly? Or, is one drop a drop too many? Parents typically supply alcohol to their children believing it is the best way to teach responsible drinking. Whether parents should provide alcohol is controversial and the evidence to inform this decision is unclear. This research will provide an in-depth understanding of the consequences of parents providing alcohol to their children and when, where and how this can be done to minimise harm. This ....Can parents teach their children to drink alcohol responsibly? Or, is one drop a drop too many? Parents typically supply alcohol to their children believing it is the best way to teach responsible drinking. Whether parents should provide alcohol is controversial and the evidence to inform this decision is unclear. This research will provide an in-depth understanding of the consequences of parents providing alcohol to their children and when, where and how this can be done to minimise harm. This is a national priority as alcohol abuse is a leading cause of injury and death among young Australians and developing the knowledge for preventive health care is essential. This research will provide parents with the information they need to give their children a healthier start to life.Read moreRead less
ADHD And Comorbidity: Implications For Clinical Practice And Molecular Genetics
Funder
National Health and Medical Research Council
Funding Amount
$284,878.00
Summary
ADHD is emerging as the most common, controversial childhood behavioural problem. Previously we have shown that much of the confusion may lie in the fact that ADHD is inherited as a continuum throughout the entire population, only some people having such a strong genetic potential that they warrant the label ADHD. The threshold to achieve this label is partly a community one, leading to the argument over who should be labelled and treated. This grant goes further in examining the possibility tha ....ADHD is emerging as the most common, controversial childhood behavioural problem. Previously we have shown that much of the confusion may lie in the fact that ADHD is inherited as a continuum throughout the entire population, only some people having such a strong genetic potential that they warrant the label ADHD. The threshold to achieve this label is partly a community one, leading to the argument over who should be labelled and treated. This grant goes further in examining the possibility that there is more than one type of ADHD. Some ADHD children have other behavioural problems such as conduct disorder or learning problems. Some have problems throughout their lives while others grow out of it. In Australia we are unique in having developed the most extensive twin databases world-wide and have already studied aspects of ADHD both in the children and their parents. In this grant we shall explore whether there are distinct genetic types of ADHD, characterised not just by their ADHD symptoms but also by the other behavioural problems they experience and by what happens as they grow-up. Such information is invaluable in developing a treatment program dealing with all aspects of the ADHD and also addresses the question of what will happen as they get older. No other study internationally has such extensive data to address these key questions., vital both to clinicians and families. Given the significant genetic component to ADHD, the next possibility is to find the genes involved in the different types. Knowing what these genes do may help in the development of medications more targeted to specific patterns of problems. Recently genes have been identified which may be involved in specific types of ADHD, as well as genes involved in associated problems such as reading disability and substance abuse. This study offers the potential to clearly identify the role of these genes and so assist in improved diagnosis and treatment interventions.Read moreRead less
Dynamic social systems and adolescent alcohol/tobacco use: A new cusp catastrophe model. This research will substantially improve our understanding of the development of adolescent high-risk behaviours. It will directly inform multimodal prevention strategies by demonstrating how substance use, peer factors, and parent relationships unfold over time. This is much needed because most prevention strategies are too simplistic to address complex precursors to alcohol/tobacco use. The research wil ....Dynamic social systems and adolescent alcohol/tobacco use: A new cusp catastrophe model. This research will substantially improve our understanding of the development of adolescent high-risk behaviours. It will directly inform multimodal prevention strategies by demonstrating how substance use, peer factors, and parent relationships unfold over time. This is much needed because most prevention strategies are too simplistic to address complex precursors to alcohol/tobacco use. The research will benefit health researchers in and beyond Australia who seek to understand behaviours that do not adhere to conventional assumptions. Collaboration with researchers from leading national and international centres will enhance Australia's research reputation and will attract postgraduates and researchers to Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100329
Funder
Australian Research Council
Funding Amount
$361,357.00
Summary
Adult drinking and child maltreatment in families, communities and societies. This project aims to measure how adult drinking is linked to child maltreatment within families, communities and societies. The project will use data from 20 countries, including Australia, and expects to develop new knowledge about links between adult drinking, fathering, community-level alcohol availability, societal drinking patterns and harms to children. Expected outcomes include national and cross-national policy ....Adult drinking and child maltreatment in families, communities and societies. This project aims to measure how adult drinking is linked to child maltreatment within families, communities and societies. The project will use data from 20 countries, including Australia, and expects to develop new knowledge about links between adult drinking, fathering, community-level alcohol availability, societal drinking patterns and harms to children. Expected outcomes include national and cross-national policy-relevant data and analysis that will inform prevention of alcohol-related child maltreatment and alcohol policy globally. This project should support reductions in the economic and human costs of alcohol-related child abuse and neglect for children, families and societies.Read moreRead less