There is huge interest in the development of bioactive peptides and proteins for the treatment of a wide range of diseases. However, the biggest challenge in the development of peptide and protein drugs is overcoming their poor stability in the human body. The aim of my research is to develop novel methods that provide therapeutically promising peptides and proteins the ability to resist the body’s natural degradation pathways so they can reach their biological target and act as effective drugs.
Improving Access To Psychological Treatment And The Mental Health Of Australians With Chronic Physical Disease.
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Most Australians will have to manage one or more chronic health conditions in their lifetime. Poor mental health is known to significantly compromise the medical treatment, self-management and, thus, the prognosis of adults with chronic physical disease. The proposed fellowship seeks to address three critical knowledge gaps limiting our ability to support the mental health of Australians with chronic physical diseases.
Communication Technologies For Supporting Patients With Multiple Morbidities Accessing Hospital Services
Funder
National Health and Medical Research Council
Funding Amount
$428,065.00
Summary
This program of research focuses on the integration of accessible remote communication technologies, including mobile devices, for helping to engage and support patients accessing hospital services. There is a specific focus on using contemporary accessible technologies to support and empower people who may have difficulty following recommendations for disease management and lifestyle behaviours to reduce their risk of severe negative health events that cause hospitalisation or death.
Targeting Inflammation-associated Macrophages For Imaging And Therapy
Funder
National Health and Medical Research Council
Funding Amount
$415,218.00
Summary
Cancer and cardiovascular disease are the most common causes of morbidity and mortality worldwide. The development of effective therapies remains a major challenge and is often associated with severe side-effects. I recently developed novel targeting reagents to effectively deliver therapeutics and diagnostic agents deep inside diseased tissues, such as tumours and atherosclerotic plaques. My research will further explore their therapeutic and imaging applications in cancer and atherosclerosis.