Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encodi ....Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encoding and retrieval processes, the model can assess how changes in different sources of interference modulate performance through the trajectory of early development. Hierarchical Bayesian estimation aims to enable a simultaneous account of multiple tasks and support future deployment in applied contexts.Read moreRead less
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
Radicalisation, Counter-Radicalisation, and De-Radicalisation: Developing a New Understanding of Terrorism in the Australian Context. Concentrating on the unique drivers of extremism within Victoria (and Australia), the study will enhance counter terrorism stakeholders' understanding of domestic radicalization. This will assist in designing policies appropriate for Australian circumstances that can: 1. pre-empt, prevent and detect radicalisation without jeopardising social cohesion and 2. reduce ....Radicalisation, Counter-Radicalisation, and De-Radicalisation: Developing a New Understanding of Terrorism in the Australian Context. Concentrating on the unique drivers of extremism within Victoria (and Australia), the study will enhance counter terrorism stakeholders' understanding of domestic radicalization. This will assist in designing policies appropriate for Australian circumstances that can: 1. pre-empt, prevent and detect radicalisation without jeopardising social cohesion and 2. reduce Australia's reliance on overseas counter-radicalisation and de-radicalisation models, where practitioners confront different community dynamics. Working towards understanding what causes radicalization in Australia, the project offers to enhance national security and by addressing local circumstances carries the prospect of creating more cost-efficient counter terrorism practices.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100211
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and developmen ....The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and development using Australian English and facilitate the development of Australian speech technology applications from automatic speech recognition and text-to-speech synthesis used in taxi and other ordering services, to hearing prostheses and talking head aids for learning-impaired children, and a range of security and forensic applications.Read moreRead less
Program evaluation of the osteoarthritis awareness hub. Persons with osteoarthritis generally have poor knowledge about their disease and its appropriate management. The aim of this project is to evaluate whether improved knowledge, and management decisions of persons with osteoarthritis, can ultimately lead to improved health outcomes.