Australian Laureate Fellowships - Grant ID: FL160100108
Funder
Australian Research Council
Funding Amount
$2,409,738.00
Summary
How the brain creates a sense of auditory space. How the brain creates a sense of auditory space. Spatial hearing is necessary for locating the source of a sound, and critical for communication in noisy listening conditions. The object of this project is to determine how the mammalian brain, including in human listeners, represents sensitivity to interaural time differences, one of the two binaural cues, and how this representation is transformed from the brainstem to the cortex. Anticipated out ....How the brain creates a sense of auditory space. How the brain creates a sense of auditory space. Spatial hearing is necessary for locating the source of a sound, and critical for communication in noisy listening conditions. The object of this project is to determine how the mammalian brain, including in human listeners, represents sensitivity to interaural time differences, one of the two binaural cues, and how this representation is transformed from the brainstem to the cortex. Anticipated outcomes include a coherent model of binaural hearing that links cellular, systems and perceptual investigations, and an understanding of the human auditory brain that should facilitate novel technologies and interventions to improve hearing function.Read moreRead less
Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to ....Listen and learn - statistical learning and the adapting auditory brain. This project aims to explore the link between rapid neural adaptation - a form of learning referred to as statistical learning - and human listening performance in noisy environments. The project aims to generate a new understanding of mechanisms that contribute to listeners' abilities to understand speech in noise, and to complex communication disorders such as dyslexia. Expected outcomes will include increased capacity to investigate a broad range of cognitive and communication functions. Benefits will include potential technologies and algorithms to assist listening (in devices such as hearing aids), language development and reading.Read moreRead less
Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project ....Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project is to address this deficiency by measuring the patterns of neural activity evoked by speech sounds across the tonotopic axis in the inferior colliculus and auditory cortex and assess the extent to which the pattern of neural activity allows discrimination between the different speech sounds.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101468
Funder
Australian Research Council
Funding Amount
$413,614.00
Summary
Context matters: from sensory processing to decision making. Contextual modulation refers to prominent changes in the processing of information in brain and perception caused by interactions across space and time. Over the past two decades, an enormous amount of work has shown that spatial contextual effects occur throughout the sensory processing hierarchy. However, there has been little work examining how temporal context effects affect information processing and operate for high-level attribu ....Context matters: from sensory processing to decision making. Contextual modulation refers to prominent changes in the processing of information in brain and perception caused by interactions across space and time. Over the past two decades, an enormous amount of work has shown that spatial contextual effects occur throughout the sensory processing hierarchy. However, there has been little work examining how temporal context effects affect information processing and operate for high-level attributes of stimuli as well as interactions of self and environment. The project aims to fill this gap to further understand the nature and mechanisms of temporal contextual modulation on sensory information processing, perception, perceptual judgement and decision making at cellular, circuit and cognitive levels.Read moreRead less
Neuronal origin of functional maps on the mammalian visual cortex. This project aims to study how the brain processes images. Basic features of objects in the visual scene seem to be coded on the visual cortex in an orderly way. By recording neurones’ electrical activity in a mammalian brain, this project aims to study how such organisation is determined at the neuronal level, namely how the individual nerves and synapses that form the brain and process the signals are organised to form the over ....Neuronal origin of functional maps on the mammalian visual cortex. This project aims to study how the brain processes images. Basic features of objects in the visual scene seem to be coded on the visual cortex in an orderly way. By recording neurones’ electrical activity in a mammalian brain, this project aims to study how such organisation is determined at the neuronal level, namely how the individual nerves and synapses that form the brain and process the signals are organised to form the overall functional architecture visible at a macroscopic level. This understanding could realise the basis of normal visual perception in robotic vision and brain-machine interfaces.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100136
Funder
Australian Research Council
Funding Amount
$385,288.00
Summary
The influence of naturalistic context on visual short-term memory. This project aims to understand visual short-term memory in natural visual environments using a combination of behavioural and brain data. Visual short-term memory is thought to be critical to complex cognitive tasks such as learning and problem solving, but how low-level image context and high-level semantic information influence short-term memory is poorly understood. This project will use advanced computational image processin ....The influence of naturalistic context on visual short-term memory. This project aims to understand visual short-term memory in natural visual environments using a combination of behavioural and brain data. Visual short-term memory is thought to be critical to complex cognitive tasks such as learning and problem solving, but how low-level image context and high-level semantic information influence short-term memory is poorly understood. This project will use advanced computational image processing tools, neuro-imaging, and psychophysical experiments to provide a comprehensive analysis of short-term memory in naturalistic images. The expected outcome is a better understanding of the neural bottlenecks that limit short-term memory, and a model that predicts memory constraints in natural visual environments.Read moreRead less
How human vision separately determines object and scene motion. This project aims to enhance understanding of how people process visual scenes containing multiple moving objects of interest. The project intends to measure human visual performance to determine how the brain processes multiple motion signals simultaneously. Expected outcomes include an increased understanding of how we are able to use an evolving visual scene to distinguish between changes due to self-motion and those due to the m ....How human vision separately determines object and scene motion. This project aims to enhance understanding of how people process visual scenes containing multiple moving objects of interest. The project intends to measure human visual performance to determine how the brain processes multiple motion signals simultaneously. Expected outcomes include an increased understanding of how we are able to use an evolving visual scene to distinguish between changes due to self-motion and those due to the motion of multiple moving objects such as crowded city footpaths and busy roads. The results will improve our understanding of failures to see moving objects in challenging viewing conditions (for example, high density traffic), and inform work in the design of autonomous driving and augmented reality display systems.Read moreRead less
Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the funct ....Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the functional organisation of the sensory cortex at a level never previously possible in the living human brain. This will provide new understanding of the neural-level networks that underpin attention and touch perception in the human brain.Read moreRead less
A role for sleep in optimising attention. All animal brains are prediction machines, which allows even tiny flies to effectively navigate complex environments. To predict what will happen next is important for guiding attention, but also for detecting anything surprising. This project aims to understand how prediction is optimized by sleep in Drosophila flies. We aim to use electrophysiology and calcium imaging to map visual prediction error signals across the fly brain, and then determine how g ....A role for sleep in optimising attention. All animal brains are prediction machines, which allows even tiny flies to effectively navigate complex environments. To predict what will happen next is important for guiding attention, but also for detecting anything surprising. This project aims to understand how prediction is optimized by sleep in Drosophila flies. We aim to use electrophysiology and calcium imaging to map visual prediction error signals across the fly brain, and then determine how genetically controlled delivery of sleep regulates the quality and distribution of these signals. This knowledge will benefit our understanding of how brains balance a capacity for prediction versus surprise, by examining how evolution has solved this difficult problem in the smallest brains.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100433
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Cortical layer specific functional imaging of the human brain. This project aims to record layer specific cortical activity in humans by leveraging ultra-high field magnetic resonance imaging. It expects to yield robust techniques for the general analysis of neuroimaging-based, layer-specific measurements. This project will progress the fields of cognitive neuroscience and neuroimaging as well as bring the field of neuroimaging closer to that of neurophysiology and thus facilitate collaboration ....Cortical layer specific functional imaging of the human brain. This project aims to record layer specific cortical activity in humans by leveraging ultra-high field magnetic resonance imaging. It expects to yield robust techniques for the general analysis of neuroimaging-based, layer-specific measurements. This project will progress the fields of cognitive neuroscience and neuroimaging as well as bring the field of neuroimaging closer to that of neurophysiology and thus facilitate collaboration among researchers.Read moreRead less