From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
Ecohydrologic functioning of ephemeral streams. This project aims to increase understanding of how surface-groundwater interactions sustain vegetation associated with ephemeral streams. One of the biggest problems faced by mining and regional development in arid regions is how to protect ecological and heritage values of ephemeral streams by minimising impacts of water abstraction and surplus discharge. The project will use environmental tracers, coupled with assessment of vegetation water use a ....Ecohydrologic functioning of ephemeral streams. This project aims to increase understanding of how surface-groundwater interactions sustain vegetation associated with ephemeral streams. One of the biggest problems faced by mining and regional development in arid regions is how to protect ecological and heritage values of ephemeral streams by minimising impacts of water abstraction and surplus discharge. The project will use environmental tracers, coupled with assessment of vegetation water use and numerical modelling, to assess resilience of ephemeral streams to changes in flows resulting from mining activities and climate-related shifts in recharge. Expected outcomes of the project include providing appropriate context for evaluating and adapting management to conserve scarce water resources. This project should significantly contribute to the sustainable management of both mineral and groundwater resources.Read moreRead less
Using large scale modelling to understand reading development and dyslexia. This project aims to construct a computational model of reading that makes quantitative predictions about reading behaviour and dyslexia. It will test theories of reading development and dyslexia based on what they predict in terms of reading performance, predictions which many theories of dyslexia do not make. The model will be in English, French and Italian, which offer rich and constraining data to test the model. The ....Using large scale modelling to understand reading development and dyslexia. This project aims to construct a computational model of reading that makes quantitative predictions about reading behaviour and dyslexia. It will test theories of reading development and dyslexia based on what they predict in terms of reading performance, predictions which many theories of dyslexia do not make. The model will be in English, French and Italian, which offer rich and constraining data to test the model. The project is expected to explain the link between reading performance and underlying influences and why dyslexia manifests differently in different languages.Read moreRead less
Where do inductive biases come from? A Bayesian investigation. This project aims to investigate the origin of our thinking and learning biases using state-of-the-art mathematical models and sophisticated experimental designs. Expected outcomes include bridging the gap between human and machine learning by pairing mathematical modelling with experimental work, forming a necessary step toward the development of machine systems that can reason like people do. This will provide significant benefits ....Where do inductive biases come from? A Bayesian investigation. This project aims to investigate the origin of our thinking and learning biases using state-of-the-art mathematical models and sophisticated experimental designs. Expected outcomes include bridging the gap between human and machine learning by pairing mathematical modelling with experimental work, forming a necessary step toward the development of machine systems that can reason like people do. This will provide significant benefits such as understanding how people operate so effectively in real environments, when even the most powerful computers struggle to handle the complexities of everyday learning problems.Read moreRead less
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light ....Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light on the evolution of Australia’s most diverse vertebrate lineage, and provide comparative data with which to interpret the lizard fossil record in Australia, and the range declines and relative extinction risks of native lizard species.Read moreRead less
Learning from others: Inductive reasoning based on human-generated data. Most of the data we see every day, from politics to gossip, comes from other people. Making inferences about such data is difficult because the people who provided it may have biases or limitations in their knowledge that we do not know about and must figure out. This project uses a series of experiments tied to normative computational models of social reasoning to explore how people solve this problem. This work has the po ....Learning from others: Inductive reasoning based on human-generated data. Most of the data we see every day, from politics to gossip, comes from other people. Making inferences about such data is difficult because the people who provided it may have biases or limitations in their knowledge that we do not know about and must figure out. This project uses a series of experiments tied to normative computational models of social reasoning to explore how people solve this problem. This work has the potential to make a major impact in understanding how information is understood and shared, especially when it is about topics that people lack firsthand knowledge about, like climate change. The computational models also have applications to the development of expert systems upon which our information economy relies.Read moreRead less
ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions i ....ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions in science. An essential function of the network will be introducing researchers end users to new tools and broadening the horizons of graduate students.Read moreRead less
Special Research Initiatives - Grant ID: SR0354804
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impac ....ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impacts of contaminated soil and wastes, and land remediation. By facilitating communication, the network enhances national and international research coordination, interaction with regulators, end-users, industry, and other stakeholders, achievement of critical mass for new initiatives, enhances research training and contributes to a critical National Priority.Read moreRead less