Discovery Early Career Researcher Award - Grant ID: DE160100755
Funder
Australian Research Council
Funding Amount
$371,000.00
Summary
Evolution of genome architecture. The project aims to understand how changes to genome architecture over evolutionary time are linked to the diversity of animal morphology. Our genome sequence is arranged into higher order structures that enable coordinated gene expression. The appropriate expression of genes in time and space is necessary to produce the multitude of cell types that make up a multicellular organism. Yet, to date, genome topology is poorly explored, especially between species. Th ....Evolution of genome architecture. The project aims to understand how changes to genome architecture over evolutionary time are linked to the diversity of animal morphology. Our genome sequence is arranged into higher order structures that enable coordinated gene expression. The appropriate expression of genes in time and space is necessary to produce the multitude of cell types that make up a multicellular organism. Yet, to date, genome topology is poorly explored, especially between species. The project involves comparisons of the 3D structure of genomes in divergent species. These findings are expected to inform the underlying principles of gene regulation in animals and species evolution.Read moreRead less
Special Research Initiatives - Grant ID: SR0354500
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
- ....ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
-facilitate training in array methodologies and bioinformatics,
-co-ordinate innovation of technologies,-provide centralised data warehousing,
-provide access to automated high-level gene annotation,
-provide data mining tools,
-set standards for data management and exchangeRead moreRead less
A Federation of cultures? Innovative approaches to multicultural accommodation. This project examines how state and federal governments can better protect and support the values, beliefs and cultural practices of different cultural and religious groups, especially in matters concerning family life, community identity and freedom of conscience, within a framework of respect for human rights.
Governing vs. opposition parties and the global financial crisis: Comparing the United Kingdom and Australia. The Australian Prime Minister has described the global financial crisis as the 'equivalent of a rolling national security crisis'. Our project, which examines the pressures upon political parties to adopt an adversarial approach to crises as an election approaches, benefits the nation by enhancing our understanding of how political systems cope with crisis. Should governing and oppositio ....Governing vs. opposition parties and the global financial crisis: Comparing the United Kingdom and Australia. The Australian Prime Minister has described the global financial crisis as the 'equivalent of a rolling national security crisis'. Our project, which examines the pressures upon political parties to adopt an adversarial approach to crises as an election approaches, benefits the nation by enhancing our understanding of how political systems cope with crisis. Should governing and opposition parties unite in order to tackle the national crisis and portray consensus to the outside world? Or should they continue to engage in routine adversary criticism, facilitating dialogue and providing a 'check' on a centralised response? Our research will help develop an understanding of Australia's capacity to respond to major economic threats.Read moreRead less
Confronting the devolution paradox: constitutional values, federal political culture and governance reform. Australia, like many countries, depends in part on devolutionary reform if its federal system of government is to adapt effectively to change. This project confronts a key barrier to reform; the ‘devolution paradox’, in which popular demands for decentralisation and diversity are confounded by conflicting political pressures for national policy uniformity and control. By mapping and compar ....Confronting the devolution paradox: constitutional values, federal political culture and governance reform. Australia, like many countries, depends in part on devolutionary reform if its federal system of government is to adapt effectively to change. This project confronts a key barrier to reform; the ‘devolution paradox’, in which popular demands for decentralisation and diversity are confounded by conflicting political pressures for national policy uniformity and control. By mapping and comparing the constitutional values and federal political culture of Australian citizens, citizens in Canada, USA and UK, and Australian reform policymakers, in more detail than ever before, it will give insights into how this key paradox might be resolved, helping unlock reform potential and restore adaptive capacity to our political system.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100154
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
The World Legal Information Institute European law collection: effective access to European legal information in English for Australian researchers. This facility will provide the most comprehensive collection of free access English language databases of European legal materials (both national and supra-national) and allow citations of European cases and articles to be tracked, improving Australian research in European law.
Does physiological plasticity of individuals render populations resilient to climate change? Abrupt environmental changes can put natural populations at risk of extinction. The project will show to what extent individuals can compensate for temperature changes and thereby render populations resilient to climate change. This research will make theoretical advances and improve the power to predict impacts of future climate change.
Nanotechnology in nature: the evolutionary significance of iridescent ultraviolet colouration in butterflies. Nanostructural colour is a novel and interesting biological phenomenon that has potential application in textile and paint industries. This research has the potential to uncover knowledge relevant to future genetic manipulation and/or artificial synthesis of this trait for industry. Fundamental benefits will include a contribution to our understanding of evolution and biological diversit ....Nanotechnology in nature: the evolutionary significance of iridescent ultraviolet colouration in butterflies. Nanostructural colour is a novel and interesting biological phenomenon that has potential application in textile and paint industries. This research has the potential to uncover knowledge relevant to future genetic manipulation and/or artificial synthesis of this trait for industry. Fundamental benefits will include a contribution to our understanding of evolution and biological diversity, enhancement of Australia's research profile, and the cultivation of new scientific expertise. This proposal also promises to benefit the Australian scientific community through the establishment of collaborative links with universities in the USA and UK, and to increase mainstream awareness of Australia's stunning natural resources.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100614
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Novel statistical algorithms and methods to quantify and partition pleiotropy between complex traits in populations. A fundamental question in biology is how common genetic effects are shared between traits or groups. For example, is cognition or human behaviour genetically identical across genders or across human population groups? This project will address these questions using multiple independent genome-wide association studies.
Discovery and characterization of new classes of small regulatory RNAs in mammals. The project will reaffirm and enhance Australian leadership in the most rapidly developing area of molecular biological and genetic research, by the application of ultra high-throughput sequencing technologies to discovery of regulatory RNAs, thereby to identify the characteristics of important regulatory pathways that underpin mammalian development, brain function and species diversity. The results of this resear ....Discovery and characterization of new classes of small regulatory RNAs in mammals. The project will reaffirm and enhance Australian leadership in the most rapidly developing area of molecular biological and genetic research, by the application of ultra high-throughput sequencing technologies to discovery of regulatory RNAs, thereby to identify the characteristics of important regulatory pathways that underpin mammalian development, brain function and species diversity. The results of this research will have wide implications and applications in biotechnology, genetic engineering, animal breeding, medical science and advanced informatics.Read moreRead less