Modernizing The Knowledge Base For Reproductive Health Care: Individual Patient Data Meta-analysis As The New Standard For Evidence Synthesis In Reproductive Health.
Funder
National Health and Medical Research Council
Funding Amount
$575,662.00
Summary
Characteristics of sick persons differ, and criteria that have been used to include them in studies may not match the individual profile of individuals who typically present to the health system. I propose a step towards more personalised medicine, which is new in the field of reproductive health. In a global collaboration, we plan to collect individual participant data of studies, and develop clinical rules and guidelines that tailor the individual profile of the sick individual.
Melanoma incidence continues to rise & it remains a leading cause of cancer death in young adults. Prevention & early detection are foundations of disease control. Drug treatments for advanced disease have recently begun to extend survival but remain ineffective in many. Utilising the extensive resources of Melanoma Institute Australia (world's largest melanoma treatment centre), this research seeks to improve outcomes of patients with difficult to treat & aggressive melanomas.
The growing momentum towards elimination of malaria and the need to control of drug-resistant parasites means that new drugs and vaccines are needed. In this Fellowship I will use the human malaria challenge system that I have developed to test whether new drugs and vaccines for malaria are working sufficiently well to justify their full development. In this system healthy volunteers are deliberately infected with malaria and then cured before they become unwell.
Better Care Of Heart And Lung Disease For Aboriginal And Torres Strait Islander People In Rural And Remote Australia
Funder
National Health and Medical Research Council
Funding Amount
$380,583.00
Summary
Lung and heart disease are major contributors to the Aboriginal Australian and Torres Strait Islander health gap. This is even more so in remote and regional Australia. This Fellowship will generate new knowledge regarding how best to prevent, diagnose and treat heart and lung disease in this setting. Based in Alice Springs, it will bring together researchers and health care providers across northern and Central Australia and link them with our leading national research institutes.