ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit ne ....ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit new cell technologies. The Centre will build critical mass and national focus in bioinformatics to generate the human capital and intellectual property that Australia needs to compete in advanced bioscience and biotechnology.Read moreRead less
Statistical methods and tools for integrative microarray analysis. Tools used for biological and medical research have been evolving and there has been an increase in high-throughput technologies such as genome sequencing and DNA microarray. The growing number of entries and the increasing availability of public microarray repositories and other sequence databases have generated the new challenge of developing tools to efficiently integrate data by different research groups. This research provi ....Statistical methods and tools for integrative microarray analysis. Tools used for biological and medical research have been evolving and there has been an increase in high-throughput technologies such as genome sequencing and DNA microarray. The growing number of entries and the increasing availability of public microarray repositories and other sequence databases have generated the new challenge of developing tools to efficiently integrate data by different research groups. This research provides new statistical methods to integrate different data sets. Its application in the biomedical field will allow researchers to effectively interpret the myriad of data generated within the community.Read moreRead less
Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of ....Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of the methodology to be developed is to expedite the discovery of new subclasses of diseases. Another is to provide prediction rules for the diagnosis and treatment of diseases.Read moreRead less
Variational methods in partial differential equations. Research in partial differential equations is a very active area of modern mathematics linking nonlinear functional analysis, calculus of variations and differential geometry to applied sciences. This project will enable Australia-based researchers to participate in the forefront of mathematical research with leading international mathematicians by establishing new collaborations, strengthening on-going collaborations and providing internat ....Variational methods in partial differential equations. Research in partial differential equations is a very active area of modern mathematics linking nonlinear functional analysis, calculus of variations and differential geometry to applied sciences. This project will enable Australia-based researchers to participate in the forefront of mathematical research with leading international mathematicians by establishing new collaborations, strengthening on-going collaborations and providing international research experience for early career researchers. As a result, this proposal will enhance Australia's distinguished reputation in analysis and further link the UQ group with a number of mathematical institutes in USA and China.Read moreRead less
Equations of Monge-Ampere type and applications. Many fundamental problems in geometry, physics and applied sciences are related to equations of Monge-Ampere type. In recent years there have been rapid developments in the study of these equations with major breakthroughs made by the proposers. This project aims at new discoveries and findings in theory and applications by resolving outstanding open problems, and enhance Australian leadership, expertise, and training in key areas of mathematics a ....Equations of Monge-Ampere type and applications. Many fundamental problems in geometry, physics and applied sciences are related to equations of Monge-Ampere type. In recent years there have been rapid developments in the study of these equations with major breakthroughs made by the proposers. This project aims at new discoveries and findings in theory and applications by resolving outstanding open problems, and enhance Australian leadership, expertise, and training in key areas of mathematics and its applications.Read moreRead less
Queueing systems and their application to telecommunication systems and dams. The aim of this project is to investigate the behaviour of large queueing systems under critical load conditions and solve problems related to large telecommunication systems, information technologies and dams. The project will have significant economic and social benefits. It will lead to the solution of high priority problems of optimal control of water resources, as well as problems in design technology of high spee ....Queueing systems and their application to telecommunication systems and dams. The aim of this project is to investigate the behaviour of large queueing systems under critical load conditions and solve problems related to large telecommunication systems, information technologies and dams. The project will have significant economic and social benefits. It will lead to the solution of high priority problems of optimal control of water resources, as well as problems in design technology of high speed telecommunication networks. It will suggest new more profitable approaches to known problems such as effective bandwidth problem, analysis and design of computer networks, optimal control of dams, and anticipate not ordinary results and solutions. It will contribute to the mathematical culture in Australia and worldwide. Read moreRead less
Geometric partial differential systems and their applications. This proposal addresses questions central to the understanding of nonlinear partial differential systems from classical, quantum field theory and liquid crystals. Applications to physical problems such as the Yang-Mills flow, Faddeev's model and liquid crystal systems are of great interest and importance in the broader scientific community. The project will yield internationally significant results in theoretical mathematics, with ....Geometric partial differential systems and their applications. This proposal addresses questions central to the understanding of nonlinear partial differential systems from classical, quantum field theory and liquid crystals. Applications to physical problems such as the Yang-Mills flow, Faddeev's model and liquid crystal systems are of great interest and importance in the broader scientific community. The project will yield internationally significant results in theoretical mathematics, with applications in physics and and other sciences. Specialist training will be provided for Australia's next generation of mathematicians. This project will enable Australian researchers to stay at the forefront of research in this area, strengthening links with a number of world-leading mathematicians.Read moreRead less
Nonlinear elliptic partial differential equations and applications. Many fundamental advances in modern technology, science and economics are driven by the analysis of nonlinear models based on nonlinear partial differential equations. In recent years there has been increasing use in applications of partial differential equations of elliptic type with major discoveries made and longstanding problems resolved by the two Chief Investigators, who have in return received many international accolades ....Nonlinear elliptic partial differential equations and applications. Many fundamental advances in modern technology, science and economics are driven by the analysis of nonlinear models based on nonlinear partial differential equations. In recent years there has been increasing use in applications of partial differential equations of elliptic type with major discoveries made and longstanding problems resolved by the two Chief Investigators, who have in return received many international accolades. This project provides for the continuation of Australian leadership in key strategic areas of international science, such as optimal transportation, as well as the continued building of related expertise and training.Read moreRead less
Nonlinear elliptic equations and applications. Many fundamental advances in modern technology, science and economics are driven through the analysis of nonlinear models based on nonlinear partial differential equations. In recent years there has been an explosion in applications of partial differential equations of elliptic type with major discoveries in underlying theory being made by the two Chief Investigators. This project provides for the continuation of Australian leadership in key st ....Nonlinear elliptic equations and applications. Many fundamental advances in modern technology, science and economics are driven through the analysis of nonlinear models based on nonlinear partial differential equations. In recent years there has been an explosion in applications of partial differential equations of elliptic type with major discoveries in underlying theory being made by the two Chief Investigators. This project provides for the continuation of Australian leadership in key strategic areas of international science, such as optimal transportation, as well as the continued building of related expertise and training.Read moreRead less
Variational problems of Monge-Ampere type. Nonlinear models dominate the frontline of modern theoretical and applied mathematics. This project concerns contemporary variational problems with analysis linked strongly to the Monge-Ampere equation, which is a fully nonlinear partial differential equation. Its study in recent years has generated complex and deep theoretical issues along with a diverse range of applications. The proposal is divided into two themes, affine maximal surfaces (involving ....Variational problems of Monge-Ampere type. Nonlinear models dominate the frontline of modern theoretical and applied mathematics. This project concerns contemporary variational problems with analysis linked strongly to the Monge-Ampere equation, which is a fully nonlinear partial differential equation. Its study in recent years has generated complex and deep theoretical issues along with a diverse range of applications. The proposal is divided into two themes, affine maximal surfaces (involving fourth order partial differential equations of Monge-Ampere type) and optimal transportation (where Monge-Ampere theory has been applied successfully in recent years). Each of these builds upon major recent research breakthroughs of the proposers.Read moreRead less