Capacity Building In Childhood And Adolescent Obesity Prevention
Funder
National Health and Medical Research Council
Funding Amount
$2,080,191.00
Summary
As obesity prevalence in children and adolescents continues to climb, there is an urgent need to build Australia's ability to undertake solutions-orientated research across several fronts. This program covers the four areas of greatest need for building research capacity in obesity prevention.Whole-of-community intervention programs: These evaluate what works and what does not work in the real world of trying to get integrated action at the community level and how to get the maximum uptake by ch ....As obesity prevalence in children and adolescents continues to climb, there is an urgent need to build Australia's ability to undertake solutions-orientated research across several fronts. This program covers the four areas of greatest need for building research capacity in obesity prevention.Whole-of-community intervention programs: These evaluate what works and what does not work in the real world of trying to get integrated action at the community level and how to get the maximum uptake by children and adolescents, their families, schools and other community settings.Assessing the cost-effectiveness of interventions: This research combines existing and emerging evidence with new modeling techniques to estimate the costs, population impacts, and cost-effectiveness of a variety of interventions.Socio-cultural contexts for obesity prevention: This research seeks to understand the various attitudes, beliefs, perceptions and values relating to food, physical activity and body size perception so that social marketing messages and intervention programs are socially and culturally appropriate and resonate with the variety of communities involved.Analysing policy processes and interventions: Policy changes are important early and powerful drivers of creating environments where the health choices are the easy choices, and the evidence base for such changes in obesity prevention is urgently needed.The four Lead Applicants in the team are all highly experienced researchers across the range of disciplines involved and are already working on a number of combined projects which will provide the research platform for the seven Team Investigators to build their skills. The Team Investigators are at various stages in their research careers and are already contributing to a significant extent. This capacity building grant will substantially boost this critical area of research by developing a team of cross-disciplinary researchers of international standing.Read moreRead less
Urban Green Space And The Health Of Aboriginal People
Funder
National Health and Medical Research Council
Funding Amount
$92,541.00
Summary
This study will look at the effect of park land, gardens and other areas of publicly accessible natural environment on the health of Aboriginal children, specifically obesity and physical exercise, living in communities located in major cities and inner regional areas.
Transgenerational Impacts Of Paternal Stress On Offspring Mental Health: Epigenetic Mechanisms And Therapeutic Interventions
Funder
National Health and Medical Research Council
Funding Amount
$572,941.00
Summary
We are following up the extraordinary, almost ‘Lamarckian’, discovery that environmental influences on fathers can affect their offspring via ‘epigenetic’ changes to the sperm. We will explore mechanisms whereby increased levels of paternal stress can cause behavioural changes in the offspring, which are relevant to depression and anxiety disorders, and how positive environmental factors, including physical activity, may induce beneficial effects. This will have major public health implications.
Re-imagining Environments For Connection And Engagement: Testing Actions For Social Prescribing In Natural Spaces
Funder
National Health and Medical Research Council
Funding Amount
$499,750.00
Summary
This project will evaluate whether and how nature-based social prescribing (NBSP) can address mental well-being. We will experimentally test the effectiveness of NBSP in promoting connection among populations experiencing social isolation and loneliness with socially oriented opportunities in safe, inclusive and accessible, green and blue outdoor urban spaces. The project will build the evidence base for the value of NBSP investments in improving mental health.
Early Environmental Determinants Of Pancreatic Islet Autoimmunity: A Pregnancy To Early Life Cohort Study In Children At Risk Of Type 1 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$1,124,069.00
Summary
The doubling in incidence of type 1 diabetes in children over the last 20 years may be explained by our modern environment, including excessive weight gain in pregnancy and early life, inadequate dietary omega- 3 fatty acids or vitamin D, or viral infections. We therefore aim to study children with a family member with type 1 diabetes from the pregnancy and through early childhood to determine the effects of the environment on their risk of developing type 1 diabetes .This will lead to strategie ....The doubling in incidence of type 1 diabetes in children over the last 20 years may be explained by our modern environment, including excessive weight gain in pregnancy and early life, inadequate dietary omega- 3 fatty acids or vitamin D, or viral infections. We therefore aim to study children with a family member with type 1 diabetes from the pregnancy and through early childhood to determine the effects of the environment on their risk of developing type 1 diabetes .This will lead to strategies to prevent type 1 diabetes.Read moreRead less
Centre Of Research Excellence For The Protection Of Pancreatic Beta Cells
Funder
National Health and Medical Research Council
Funding Amount
$2,607,110.00
Summary
Type 1 diabetes (T1D) is an autoimmune disorder that results in the destruction of the pancreatic beta cells. The overall aim of the CRE is to elucidate the gene-environment interactions and modifiable environmental exposures that are driving the development of islet autoimmunity and progression to T1D. The CRE will unify and add value to new and established collaborations with multi-disciplinary input from genomics, bioinformatics and systems biology into the investigation of T1D.
Built Environments And Child Health In WalEs And AuStralia (BEACHES)
Funder
National Health and Medical Research Council
Funding Amount
$797,256.00
Summary
A better understanding of how the built environment drives obesity in children will inform evidence-based planning policy and practice strategies to prevent the rise in non-communicable diseases (NCDs) in future generations. We will bring together five large UK and Australian cohort studies to understand how complex and interacting built environment factors influence modifiable risk factors (physical inactivity, sedentary time, unhealthy diet) for NCD’s across childhood.
The Darwin Prospective Melioidosis Study: Years 27-31
Funder
National Health and Medical Research Council
Funding Amount
$1,281,718.00
Summary
The Darwin Prospective Melioidosis Study has documented 914 cases since 1989, with 115 fatalities. A surge in Darwin melioidosis cases over the past 5 years has been linked to urban development and the discovery of a new bacterial strain. Whole genome sequencing of our unique 25+ year set of bacteria and their linked patient data will unravel the changing epidemiology and identify important virulence factors, forming a foundation for future diagnostics, therapeutics, and vaccines.