Suboptimal Sleep And Unhealthy Brain Ageing: Improving Outcomes Through Treatment
Funder
National Health and Medical Research Council
Funding Amount
$632,705.00
Summary
My research will address limitations in our understanding of the impact of sleep characteristics on memory and thinking abilities and biological markers of brain health in older adults, by; 1) exploring these relationships over time, and 2) enabling direct assessment of the effect of improved sleep on memory and thinking, and markers of brain health, following sleep-improvement therapy. My results will contribute to the development of strategies aimed at promoting healthy brain ageing.
Developing Robust Biomarkers For Vascular Cognitive Impairment And Dementia: Adding V To The ATN Research Framework
Funder
National Health and Medical Research Council
Funding Amount
$3,289,215.00
Summary
The main objective of this research is to develop biomarkers for vascular dementia. It builds upon the longitudinal studies and international consortia that I lead. The studies will use multimodal MRI, advanced retinal imaging, mass spectrometry and other techniques to establish and validate robust biomarkers of vascular contributions to dementia. The findings will help achieve a definitive diagnosis of vascular dementia and quantify vascular pathology in someone with dementia.
Challenging Behaviours In Dementia: Mechanisms, Assessment And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
This research program focuses on the behavioural symptoms of dementia. These symptoms are common, and can range from reduced motivation and empathy to overeating, gambling and socially-inappropriate or repetitive behaviour. Notably, these behaviours are challenging for carers and families to cope with, and often lead to patients being placed into aged care facilities. My research aims to understand why these symptoms develop and how we can manage these behaviours effectively.
Development Of Novel Therapies To Treat Obesity Related Metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,981,372.00
Summary
Obesity results in the development of many diseases particularly as we age. These diseases include type 2 diabetes, fatty liver diasease and dementia. This research rpogram with develop new strategies and therapies targeted to treat these obesity related diseases.
Patient-centred Volunteer Program For People With Dementia: A Stepped Wedge Cluster Randomised Controlled Trial Of The MyCare Ageing Program
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
The MyCare Ageing program provides hospitalised patients with dementia and/or delirium with tailored emotional and practical support via trained volunteers in hospital and in the transition home. This project will provide critical information on whether MyCare Ageing works to reduce future hospitalisations and prevent poor patient outcomes, the factors that impact on how the program is delivered in hospital and in the community, and whether the program is cost-effective.