Effects of prosthesis design on bone remodelling and longevity of dental restorations. The project targets both the 'Promoting and Maintaining Good Health' and 'Advanced Materials' designated research priority areas. The research will underpin Australia's leading role on some emerging interdisciplinary frontiers of biomechanics, biomaterials, health sciences and biomedical software. The development of computer aided clinical plan will help optimise dental restorations for 'long-term success'. Th ....Effects of prosthesis design on bone remodelling and longevity of dental restorations. The project targets both the 'Promoting and Maintaining Good Health' and 'Advanced Materials' designated research priority areas. The research will underpin Australia's leading role on some emerging interdisciplinary frontiers of biomechanics, biomaterials, health sciences and biomedical software. The development of computer aided clinical plan will help optimise dental restorations for 'long-term success'. The benefit will be to improve the ongoing performance and longevity of dental restoration, which complies with the highly demanding national goal of 'ageing well'. The study will also provide a new means to improve the therapy effect for many young Australians' effort towards a 'healthy start to their life'.Read moreRead less
Topography Optimisation of Implants for Enhancing Osseointegration. With recent increased life expectancy, the ratio of implant recipients to total population has dramatically increased. The project will address a critical issue in ensuring long-term success of prosthetic treatment. The proposed computational multiscale modelling will provide a sound scientific alternative means to optimisation of overall implant design including surface topography. The anticipated outcomes of this research will ....Topography Optimisation of Implants for Enhancing Osseointegration. With recent increased life expectancy, the ratio of implant recipients to total population has dramatically increased. The project will address a critical issue in ensuring long-term success of prosthetic treatment. The proposed computational multiscale modelling will provide a sound scientific alternative means to optimisation of overall implant design including surface topography. The anticipated outcomes of this research will help improve the quality of prosthetic therapy, and benefit our prosthodontic and orthopaedic professionals and their patients. The study clearly aligns with the national research goals of frontier technologies and maintaining good health.Read moreRead less
Nano-mechanical and nano-structural investigation of dentine: unravelling a novel nano-scale regulator of high durability of mineralised tissues. This project proposes that proteoglycans (PG) are key regulators of the high durability of dentine. PGs are primarily responsible for the structural organization of collagen in all vertebrates, however virtually nothing is known about their role on the biomechanics of mineralized tissues. This study aims to thoroughly address this question.
Design Optimisation for Fabrication of Ceramic Prosthetic Devices. The project aims to develop computer aided design and fabrication for ceramic prosthesis. It will help establish a world-class biomedical instrumentation company having part of its research and development in Australia. The study will not only foster domestic research expertise, but also provide the local prosthetic community and biomedical industry with an opportunity to participate in further innovation of biomaterials, biomedi ....Design Optimisation for Fabrication of Ceramic Prosthetic Devices. The project aims to develop computer aided design and fabrication for ceramic prosthesis. It will help establish a world-class biomedical instrumentation company having part of its research and development in Australia. The study will not only foster domestic research expertise, but also provide the local prosthetic community and biomedical industry with an opportunity to participate in further innovation of biomaterials, biomedical software and equipment. The outcomes will directly benefit the Australian prosthetic profession. Improvement in prosthesis restorative longevity for our increasing ageing population will support the national research goal of ageing well, ageing productively.Read moreRead less
Multiscale Study on Biomechanical Roles of Soft Tissue on Bone Remodelling. The project aims to increase our knowledge of the processes of bone remodelling and the role of soft tissue in this process. Mechanical force is a key stimulus for regulating bone remodelling. A significant question in biomechanics is why orthodontics only use very small forces (1 Newton) to generate significant oral bone remodelling, whereas prosthodontics that apply three orders of magnitude higher forces (~1000 Newton ....Multiscale Study on Biomechanical Roles of Soft Tissue on Bone Remodelling. The project aims to increase our knowledge of the processes of bone remodelling and the role of soft tissue in this process. Mechanical force is a key stimulus for regulating bone remodelling. A significant question in biomechanics is why orthodontics only use very small forces (1 Newton) to generate significant oral bone remodelling, whereas prosthodontics that apply three orders of magnitude higher forces (~1000 Newton) do not move dental implants. This project aims to develop new multiscale modelling and remodelling techniques in computational mechanics to explore the roles played by connective soft tissue in bone adaptation. Expected project outcomes would increase our understanding in biomechanics and affect health care disciplines such as orthodontics, prosthodontics and orthopaedics.Read moreRead less
Topology Optimisation of Periodic Structures for Stent Design. Stenting therapy offers new therapeutical strategies to improve the quality of healthcare for numerous cardiovascular disease patients. This project will address the critical issues in stent design involving the delivery, dilatation and ongoing interaction with blood vessel and fluid. The novel topological configurations are expected to bring significant improvement to stent ensuring long-term success. The numerical techniques to be ....Topology Optimisation of Periodic Structures for Stent Design. Stenting therapy offers new therapeutical strategies to improve the quality of healthcare for numerous cardiovascular disease patients. This project will address the critical issues in stent design involving the delivery, dilatation and ongoing interaction with blood vessel and fluid. The novel topological configurations are expected to bring significant improvement to stent ensuring long-term success. The numerical techniques to be developed for optimising topology will provide new tools for design of periodic structures, making a broader impact on an important class of engineering structures and thus benefiting many relevant fields.Read moreRead less
Advanced Intramedullary Nailing Systems. The proposed project is aimed at developing advanced orthopaedic implants (intramedullary nails and associated locking screws) commonly used for bone fracture repair. These new generation metallic implants will be developed using a comprehensive research approach centred on physico-chemical and mechanical properties investigations. A new generation of intramedullary nailing systems with superior design and mechanical properties (small diameter and high st ....Advanced Intramedullary Nailing Systems. The proposed project is aimed at developing advanced orthopaedic implants (intramedullary nails and associated locking screws) commonly used for bone fracture repair. These new generation metallic implants will be developed using a comprehensive research approach centred on physico-chemical and mechanical properties investigations. A new generation of intramedullary nailing systems with superior design and mechanical properties (small diameter and high strength) and improved bone fixation is the key expected outcome. The knowledge generated in the project is expected to lead to the growth of the Industry Partner (Austofix). Training of a world class researcher in the multidisciplinary field of biomaterials will be an additional outcome.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100136
Funder
Australian Research Council
Funding Amount
$557,389.00
Summary
Large-volume, multi-use micro-computed tomography. This project aims to augment the existing X-ray micro-computed tomography (CT) scanning capabilities in South Australia and Australia by introducing a large-volume micro-CT scanner. This will enable three-dimensional scanning of large and heavy samples including whole machine parts, limbs/segments, prosthesis devices, large animals and vertebrates, fossils and plant root systems. The project expects to allow experimental testing rigs to be plac ....Large-volume, multi-use micro-computed tomography. This project aims to augment the existing X-ray micro-computed tomography (CT) scanning capabilities in South Australia and Australia by introducing a large-volume micro-CT scanner. This will enable three-dimensional scanning of large and heavy samples including whole machine parts, limbs/segments, prosthesis devices, large animals and vertebrates, fossils and plant root systems. The project expects to allow experimental testing rigs to be placed inside the scanner to test samples, such as mechanical testing of femurs or medical devices, while scanning, to study the structure-function relationships. This will build unlimited computer simulations of mechanical tests, valuable for precious specimens. Benefits will include aiding in risk reduction, decision making on products and a higher quality workforce.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100095
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
High-resolution X-ray micro computed tomography supporting West Australian geo-, physical and biological science. An X-ray micro computed tomography facility will provide West Australian researchers with much needed access to cutting-edge instrumentation for high-resolution three-dimensional imaging. This facility will support major research programs in key disciplines, including minerals and mining, energy, medical and biological sciences.