Microbial Indicators For The Conservative Therapy Of Dentinal Caries.
Funder
National Health and Medical Research Council
Funding Amount
$429,129.00
Summary
Recent developments in dental restorative materials create potential for conservative therapy of advanced tooth decay by sealing in the complex infecting microbial populations. Our studies have disclosed these microbial populations and indicated patterns. Planned analysis will follow the fate of bacterial populations that are sealed in this manner to determine the relationship to either resolution or progression of the lesion, leading to diagnostic indicators for clinical management.
Sealing Ability Of Adhesive Restorations In Caries And Non-caries Affected Teeth.
Funder
National Health and Medical Research Council
Funding Amount
$46,081.00
Summary
Dental fillings are used in treating tooth decay. Tooth coloured materials have become more common than metal fillings. A factor in determining the effectiveness of these adhesive restorations is analysing the bond strength between the filling and tooth. A poor bond between the restorative material and tooth is likely to produce problems such as tooth sensitivity and recurrent decay. We intend to investigate the sealing ability of adhesive restorations to carious affected teeth and sound teeth.
Intervention Strategies For The Prevention Of Early Childhood Caries
Funder
National Health and Medical Research Council
Funding Amount
$125,000.00
Summary
Rampant dental decay in young children remains an important challenge for preventive dentistry. Although it is a preventable disease, the prevalence is high in many disadvantaged communities. The study will examine a few intervention programs to determine their effectiveness in preventing early childhood decay. These include brushing the teeth with a safe, dental antibacterial gel compared to traditional oral hygiene methods. Brushing with antibacterial gels at crucial times during the establish ....Rampant dental decay in young children remains an important challenge for preventive dentistry. Although it is a preventable disease, the prevalence is high in many disadvantaged communities. The study will examine a few intervention programs to determine their effectiveness in preventing early childhood decay. These include brushing the teeth with a safe, dental antibacterial gel compared to traditional oral hygiene methods. Brushing with antibacterial gels at crucial times during the establishment of the oral flora is likely to prevent decay-causing bacteria from colonising a child’s mouth, so that the risk of dental decay is reduced, not only during childhood, but possibly extending to adulthood as well.Read moreRead less
The Effectiveness Of Consuming Fluoridated Water In Reducing Children's Caries Experience.
Funder
National Health and Medical Research Council
Funding Amount
$507,090.00
Summary
The extent to which water fluoridation has contributed to the considerable reduction of dental decay in children in recent times in Australia is unclear, due perhaps to the increasing availability of fluoride in other sources such as toothpaste, drops, tablets, and professional applications. It is proposed to monitor for approximately three years a sample of 23,140 primary and secondary school children to examine the precise contribution of consuming fluoridated water to new tooth decay. The pro ....The extent to which water fluoridation has contributed to the considerable reduction of dental decay in children in recent times in Australia is unclear, due perhaps to the increasing availability of fluoride in other sources such as toothpaste, drops, tablets, and professional applications. It is proposed to monitor for approximately three years a sample of 23,140 primary and secondary school children to examine the precise contribution of consuming fluoridated water to new tooth decay. The project also aims to examine the comparative role of diet, toothbrushing, socioeconomic status, and other factors in the development of tooth decay. Given the widespread fluoridation of water supplies in Australia, and the continuing public debate over the extent of its effectiveness in preventing tooth decay, one of the project's most significant features is its capacity to contribute to a calculation of the cost effectiveness of water fluoridation as a public health strategy for the reduction of decay experience in children. The findings of the project will provide a strong argument for either eliminating fluoride from the water supply due to it's negligable public benefit or extending water fluoridation to the remaining quarter of the Australian population who are currently being disadvantaged by not having access to the health benefits derived from consuming fluoridated water.Read moreRead less
Development Of Antimicrobial Peptides Targeting Oral Pathogenic Bacteria
Funder
National Health and Medical Research Council
Funding Amount
$663,350.00
Summary
The bacterial associated oral diseases; periodontitis and caries are major public health problems. The prevalence of these diseases and increasing bacterial antibiotic resistance has meant there is a need to develop new therapies. This project addresses this by modifying a novel class of antibiotics/antiseptics �antimicrobial peptides� to target oral bacteria and testing them using a newly developed screening method. This project will lead to new therapies for periodontitis and caries.