Discovery Early Career Researcher Award - Grant ID: DE130101550
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Functional polymer encapsulation to enhance biological performance of implantable materials. This project will develop biomaterial films from essential oils using a low-cost 'green' technology. Applied to commercial biomaterials, these films will minimise infections and inflammations commonly associated with implants. These films will also enable clinical use of metallic resorbable implants for tissue engineering and function restoration.
Development of a market relevant DNA nano-vaccine platform. DNA vaccine technology can potentially provide a rapid response to existing or new pathogens, but its market success has been limited. By addressing key scientific and technical challenges, this project aims to develop a new and cost-effective DNA nanovaccine platform using a multiscale engineering approach. It is anticipated that novel nanoparticles for DNA delivery and an end-user-driven DNA vaccine technology with enhanced immunogeni ....Development of a market relevant DNA nano-vaccine platform. DNA vaccine technology can potentially provide a rapid response to existing or new pathogens, but its market success has been limited. By addressing key scientific and technical challenges, this project aims to develop a new and cost-effective DNA nanovaccine platform using a multiscale engineering approach. It is anticipated that novel nanoparticles for DNA delivery and an end-user-driven DNA vaccine technology with enhanced immunogenicity, stability and safety will be generated. Expected outcomes include new knowledge in nanomaterial science and a market ready technology platform, improving Australia’s capabilities in nanobiotechnology and vaccine development, as well as delivering a new value-added product for the Industry Partner. Read moreRead less
Development of Unprecedented Aluminosilicate Adjuvants. High-performance adjuvants are essential components of vaccine technology. Aluminium-based adjuvants are widely used, but provide weak cellular immunity and possible risk of neurotoxicity. Combining state-of-the-art nanotechnology and classic coordination chemistry, this project aims to apply a new design principle to create novel mesoporous aluminosilicate nanoparticles with alkalinity, for use as nanoadjuvants. This project expects to adv ....Development of Unprecedented Aluminosilicate Adjuvants. High-performance adjuvants are essential components of vaccine technology. Aluminium-based adjuvants are widely used, but provide weak cellular immunity and possible risk of neurotoxicity. Combining state-of-the-art nanotechnology and classic coordination chemistry, this project aims to apply a new design principle to create novel mesoporous aluminosilicate nanoparticles with alkalinity, for use as nanoadjuvants. This project expects to advance knowledge of how immune systems respond to changes in chemistry and nanostructure of aluminosilicate materials and enable the design of nanoadjuvants with enhanced cellular immunity and reduced toxicity. Outcomes include a new family of functional materials with unprecedented adjuvant performance.Read moreRead less
Next-Generation Multifunctional Nanoparticles for mRNA Transfection. This project aims to engineer a multifunctional nanoparticle platform tailored for mRNA delivery. An innovative assembly approach will be used to design nanoparticles with adjustable composition, asymmetry and surface topography. Uniquely, three functions will be integrated in one nanoparticle, with the goal to enhance transfection efficiency in target cells. This project expects to advance knowledge of mRNA transfection mechan ....Next-Generation Multifunctional Nanoparticles for mRNA Transfection. This project aims to engineer a multifunctional nanoparticle platform tailored for mRNA delivery. An innovative assembly approach will be used to design nanoparticles with adjustable composition, asymmetry and surface topography. Uniquely, three functions will be integrated in one nanoparticle, with the goal to enhance transfection efficiency in target cells. This project expects to advance knowledge of mRNA transfection mechanisms, and determine how cell-type dependent particle-mRNA interactions correlate with the nanoparticle structure and delivery performance. Outcomes include a new family of functional materials with improved mRNA delivery performance over benchmark systems to facilitate and broaden the application of mRNA technology.Read moreRead less
Vapour phase detection of chemical warfare agents. This project aims to create luminescent plastic optoelectronic materials that can detect airborne chemical warfare agents, particularly nerve agents. Such agents are often odourless and invisible at lethal concentrations, so technology must detect and identify them before exposure. The intended outcomes are design rules for sensitive and selective materials that can be used in a handheld infield detector to sense chemical warfare agents based on ....Vapour phase detection of chemical warfare agents. This project aims to create luminescent plastic optoelectronic materials that can detect airborne chemical warfare agents, particularly nerve agents. Such agents are often odourless and invisible at lethal concentrations, so technology must detect and identify them before exposure. The intended outcomes are design rules for sensitive and selective materials that can be used in a handheld infield detector to sense chemical warfare agents based on the materials’ photophysical properties, and new analytical methods and sensing protocols. This research will be of interest to security agencies in Australia and internationally, and will better protect our military.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101156
Funder
Australian Research Council
Funding Amount
$426,476.00
Summary
Preconcentrators for vapour detection of explosive material. This Project’s aim is to develop a preconcentrator technology for the in-field detection of explosive vapours that have low concentrations in air. Low explosive vapour concentration limits the efficacy of portable detectors. Current preconcentrator technologies sorb vapours but require heat to release the concentrated material limiting their use to non-portable detectors. This project is expected to deliver materials and a device modul ....Preconcentrators for vapour detection of explosive material. This Project’s aim is to develop a preconcentrator technology for the in-field detection of explosive vapours that have low concentrations in air. Low explosive vapour concentration limits the efficacy of portable detectors. Current preconcentrator technologies sorb vapours but require heat to release the concentrated material limiting their use to non-portable detectors. This project is expected to deliver materials and a device module for a preconcentrator technology that will sorb explosive analytes, have low power requirements and be compatible with hand held explosives detectors. Security and law enforcement agencies should directly benefit from these findings, which would advance their safety and that of the community as a whole.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101030
Funder
Australian Research Council
Funding Amount
$368,446.00
Summary
Monoatomic metal doping of carbon-based nanomaterials for hydrogen storage. This project aims to present a new concept of monoatomic metal doped carbon-based nanomaterials as advanced solid-state hydrogen storage materials (S-HSMs) for hydrogen fuel cells. The key feature for this synthesis is the use of the unique “defect” structures in carbon lattice as the efficient anchoring sites to immobilise the metal species at atomic level. This project is expected to create new knowledge of atomic inte ....Monoatomic metal doping of carbon-based nanomaterials for hydrogen storage. This project aims to present a new concept of monoatomic metal doped carbon-based nanomaterials as advanced solid-state hydrogen storage materials (S-HSMs) for hydrogen fuel cells. The key feature for this synthesis is the use of the unique “defect” structures in carbon lattice as the efficient anchoring sites to immobilise the metal species at atomic level. This project is expected to create new knowledge of atomic interface catalysis and develop practical applications of S-HSMs in storage tanks for fuel cells, leading to reduction of carbon dioxide emissions and alleviation of air pollution. The success of this project will greatly enhance the Australian clean energy industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101190
Funder
Australian Research Council
Funding Amount
$359,446.00
Summary
Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collec ....Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collection. Expected project outcomes will place Australia at the forefront of practical low-cost and large-scale solar energy conversion technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100892
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structur ....Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structural design and surface modification. The success of the project will benefit Australia’s booming graphite industry and promote Australian competitiveness in wearable electronics markets.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190101351
Funder
Australian Research Council
Funding Amount
$406,000.00
Summary
Designing new perovskite quantum dots for efficient solar energy conversion. This project aims to rationally design new perovskite quantum dots featuring prominent phase and thermal stability in humid air and remarkable optoelectronic properties. These will be crucial for the development of next-generation flexible, lightweight solar energy conversion devices. This project expects to generate new knowledge in the fundamental mechanism of functional materials for more efficient solar energy conve ....Designing new perovskite quantum dots for efficient solar energy conversion. This project aims to rationally design new perovskite quantum dots featuring prominent phase and thermal stability in humid air and remarkable optoelectronic properties. These will be crucial for the development of next-generation flexible, lightweight solar energy conversion devices. This project expects to generate new knowledge in the fundamental mechanism of functional materials for more efficient solar energy conversion. Expected outcomes include new advanced materials and commercially compelling technology for sustainable and decentralised energy utilisation. This project will position Australia at the frontier of clean energy, flexible optoelectronics and related research areas.Read moreRead less