The genomic landscape of speciation in hominins and other taxa. This project will develop a new analytical framework to build detailed genomic maps of speciation genes across different taxa, to determine whether observed speciation is the result of background selection and demography alone, or whether there are actual barriers to gene flow and introgressed DNA. The model will provide novel insights into the mechanistic basis of speciation, specifically whether a common set of genes or pathways a ....The genomic landscape of speciation in hominins and other taxa. This project will develop a new analytical framework to build detailed genomic maps of speciation genes across different taxa, to determine whether observed speciation is the result of background selection and demography alone, or whether there are actual barriers to gene flow and introgressed DNA. The model will provide novel insights into the mechanistic basis of speciation, specifically whether a common set of genes or pathways are central to the speciation process. The framework will be developed using the large genomic datasets available across a range of plant and animal species. Applying the model to a modern human population dataset will elucidate the role introgressed DNA from Denisovan and Neanderthals has played in shaping human evolutionary history and may provide novel insights into the genetic basis of disease.Read moreRead less
Theorising and understanding how policy processes affect uptake of evidence on social determinants of health and equity in Australian health policy. This project determines how to apply recent recommendations from the World Health Organisation about the social determinants of health to Australia. Analysis of health sector policies, including detailed case studies, will determine how governments can shape policy and implementation processes to improve Australia’s health.
Road safety and Aboriginal people. This study will involve an in-depth examination of factors underlying the high involvement in road crashes by Aboriginal people in Australia. Using mixed methods in six communities across NSW and South Australia it will inform development of new programs aimed at closing the gap in this important area.
Policy orientation of non-health sectors to social determinants of health. This project aims to advance understanding of how Australian government policies in four sectors (justice, environment, planning, and industry) are oriented to action on social determinants of health equity (SDHE), including Indigenous health. Evidence shows that government policy in all sectors affects health. The World Health Organization and the United Nations have called for whole-of-government approaches to SDHE. The ....Policy orientation of non-health sectors to social determinants of health. This project aims to advance understanding of how Australian government policies in four sectors (justice, environment, planning, and industry) are oriented to action on social determinants of health equity (SDHE), including Indigenous health. Evidence shows that government policy in all sectors affects health. The World Health Organization and the United Nations have called for whole-of-government approaches to SDHE. The project plans to apply theory to understand how policy values and strategies in the selected sectors provide for or present barriers to this approach. Expected project outcomes will produce evidence for policy-makers on how to strengthen policy coherence across sectors to address SDHE more effectively in order to promote Australian health and reduce health inequities.Read moreRead less
Investigating social, built and physical environment factors for remote Indigenous communities, and their relationships with cardiometabolic outcomes. This study with 74 remote Indigenous communities will be the first to evaluate features of their social, built and physical environments in relation to cardiometabolic risks and diseases. Policy-relevant results will identify features of environments to be targeted to assist reducing chronic diseases for Indigenous peoples in remote communities.