Development of genetic technology for rodent population suppression. Vertebrate pests cost Australia over $1 billion each year in agricultural losses and environmental damage and novel strategies are urgently required to tackle this massive challenge. Newly proposed “gene drives”, which might rapidly spread through populations, have enormous potential for the sustained management and even eradication of pests. Through innovative application of cutting-edge genome editing approaches, this proposa ....Development of genetic technology for rodent population suppression. Vertebrate pests cost Australia over $1 billion each year in agricultural losses and environmental damage and novel strategies are urgently required to tackle this massive challenge. Newly proposed “gene drives”, which might rapidly spread through populations, have enormous potential for the sustained management and even eradication of pests. Through innovative application of cutting-edge genome editing approaches, this proposal aims to develop gene drive technology in mice as a prototypical vertebrate pest species. We will also develop cutting-edge mathematical models of rodent gene drives to identify crucial parameters for efficacious employment and investigate potential for impact on non-target populations.Read moreRead less
The biology and epidemiology of the grapevine canker fungi, Botryosphaeria sp. Decline and dieback of grapevines is becoming an increasing problem for the viticulture industry in NSW. Recently, species of the fungus Botryosphaeria, were isolated from grapevines exhibiting these symptoms. In order to understand the biology and epidemiology of the causal organisms, we aim to; (i) determine species of Botryosphaeria present in NSW vineyards; (ii) determine which species are pathogenic on grapevines ....The biology and epidemiology of the grapevine canker fungi, Botryosphaeria sp. Decline and dieback of grapevines is becoming an increasing problem for the viticulture industry in NSW. Recently, species of the fungus Botryosphaeria, were isolated from grapevines exhibiting these symptoms. In order to understand the biology and epidemiology of the causal organisms, we aim to; (i) determine species of Botryosphaeria present in NSW vineyards; (ii) determine which species are pathogenic on grapevines; (iii) characterise the genetic diversity of strains and; (iv) screen fungicides for the control of these fungi. Information on the species, their biology and pathogenicity on grapevines, will enable the development of appropriate management strategies for its control and may lead to the development of molecular tools to identify species of Botryosphaeria.Read moreRead less
Promoting engagement with life in older adulthood. This project aims to examine engagement in meaningful activities among older adults. Increasing older adults' engagement could promote direct benefits for social integration, well-being and better quality of life. The project is expected to generate new knowledge on programs that effectively promote engagement, as well as evaluating a new tailored approach to promoting engagement that aligns with individuals' unique strengths, capabilities and ....Promoting engagement with life in older adulthood. This project aims to examine engagement in meaningful activities among older adults. Increasing older adults' engagement could promote direct benefits for social integration, well-being and better quality of life. The project is expected to generate new knowledge on programs that effectively promote engagement, as well as evaluating a new tailored approach to promoting engagement that aligns with individuals' unique strengths, capabilities and values. The findings aim to provide benefits for community organisations and aged care service providers adopting innovative approaches to promoting ageing well.
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Identifying the diversity and evolution of loci associated with adaptation to aridity/heat and salinity in ancient cereal crops. This project will use ancient grains of wheat, barley and rye to find 'lost' genetic diversity at key genes associated with resistance to aridity, salt and disease. This project will make the proteins of key genes, and study their interaction with the environment over time by measuring ions in the grains to reveal the ancient environmental conditions.
Using genetics to recover Australia's lost history. This project aims to use historic hair samples collected by anthropological expeditions in the early 20th Century to generate the first genetic map of Aboriginal Australia – in order to reconstruct Australia’s pre-European genetic and cultural past. The map and the detailed contextual and genealogical information from museum archives will assist Aboriginal communities and individuals to reconstruct their personal and family history and trace an ....Using genetics to recover Australia's lost history. This project aims to use historic hair samples collected by anthropological expeditions in the early 20th Century to generate the first genetic map of Aboriginal Australia – in order to reconstruct Australia’s pre-European genetic and cultural past. The map and the detailed contextual and genealogical information from museum archives will assist Aboriginal communities and individuals to reconstruct their personal and family history and trace ancestry and augment oral or written records. The combination of cutting-edge science, detailed archival research, and a comprehensive family outreach and reporting program will be a step change in assisting Australia’s reconciliation process, the Stolen Generation, and repatriation of Indigenous remains.Read moreRead less
Developing new methods to retrieve and analyse preserved genetic information. This project will position Australia at the leading edge of research into preserved DNA, and will use innovative molecular biology approaches to develop a range of new forensic, archaeological and medical applications. It will build Australian knowledge and scientific capacity by developing core expertise and training personnel in areas important for biosecurity, customs and quarantine, forensics/counter-terrorism, and ....Developing new methods to retrieve and analyse preserved genetic information. This project will position Australia at the leading edge of research into preserved DNA, and will use innovative molecular biology approaches to develop a range of new forensic, archaeological and medical applications. It will build Australian knowledge and scientific capacity by developing core expertise and training personnel in areas important for biosecurity, customs and quarantine, forensics/counter-terrorism, and studies of climate change. It will also create and foster research innovation in molecular biology with spin-offs for evolution, archaeology, medical and conservation biology research, and will also encourage involvement with the rapidly expanding field of genomics and bioinformatics.Read moreRead less
Evolution, disease and extinction - using ancient and modern Deoxyribonucleic acid (DNA) to investigate molecular evolution in the Tasmanian devil. The Tasmanian devil is Australia's largest living marsupial carnivore and one of Tasmania's key tourism icons. Extinction in the wild will have long-term impacts on Tasmanian native ecosystems and economy. This study will provide critical genetic data and tools to monitor and prioritise conservation strategies, including insurance populations and dis ....Evolution, disease and extinction - using ancient and modern Deoxyribonucleic acid (DNA) to investigate molecular evolution in the Tasmanian devil. The Tasmanian devil is Australia's largest living marsupial carnivore and one of Tasmania's key tourism icons. Extinction in the wild will have long-term impacts on Tasmanian native ecosystems and economy. This study will provide critical genetic data and tools to monitor and prioritise conservation strategies, including insurance populations and disease suppression, aimed at preventing extinction. It will strengthen ongoing conservation programs carried out by the Save the Tasmanian Devil Program and will help publicise the plight of the devil both nationally and internationally.Read moreRead less
Exploring genetic diversity to identify new heat tolerance genes in wheat. This project aims to improve the selection and development of heat-tolerant wheat varieties. Heatwaves seriously reduce wheat yields worldwide, and the situation will worsen with climate variation. This project aims to apply a broad genetic scan to identify the main chromosome regions controlling heat tolerance at the sensitive flowering stage in Australian and European wheat varieties. It is expected that this knowledge ....Exploring genetic diversity to identify new heat tolerance genes in wheat. This project aims to improve the selection and development of heat-tolerant wheat varieties. Heatwaves seriously reduce wheat yields worldwide, and the situation will worsen with climate variation. This project aims to apply a broad genetic scan to identify the main chromosome regions controlling heat tolerance at the sensitive flowering stage in Australian and European wheat varieties. It is expected that this knowledge will deliver crucial breeders’ tools to select heat-tolerant varieties. The project also aims to identify genes most likely to control tolerance at these chromosome locations using gene expression profiling data, trait associations and knowledge of heat-tolerance genes from other species. It is expected that these genes will reveal molecular mechanisms of heat tolerance and create new opportunities to engineer superior levels of tolerance in cereals.Read moreRead less
The role of online social networks in successful ageing: benefitting from 'who you know' at older ages. The project will increase understanding of how online social networking contributes to successful ageing through partnering, economic and voluntary activity, family and social connectedness. The findings will inform policy recommendations, social interventions and education programs designed to enhance 'ageing well, ageing productively'. These are expected to benefit the health and well-being ....The role of online social networks in successful ageing: benefitting from 'who you know' at older ages. The project will increase understanding of how online social networking contributes to successful ageing through partnering, economic and voluntary activity, family and social connectedness. The findings will inform policy recommendations, social interventions and education programs designed to enhance 'ageing well, ageing productively'. These are expected to benefit the health and well-being of older Australians, with economic benefits of increased contributions to society and fewer demands on services. Social and economic benefits are also expected from insights into reducing the technological and psychological barriers that prevent older people from benefiting from the Internet and online social networking.Read moreRead less
Pioneering seed solutions for the industrial hemp industry. This project aims to develop the next generation of elite industrial hemp cultivars, grown for their seed with high protein and oil contents, that are drought resistant and make minimal THC, teamed with research into their feminisation to provide a safer and better method of producing premium female seed to supply to growers. Project outcomes will include increased fundamental knowledge of drought tolerance, cannabinoid biosynthesis and ....Pioneering seed solutions for the industrial hemp industry. This project aims to develop the next generation of elite industrial hemp cultivars, grown for their seed with high protein and oil contents, that are drought resistant and make minimal THC, teamed with research into their feminisation to provide a safer and better method of producing premium female seed to supply to growers. Project outcomes will include increased fundamental knowledge of drought tolerance, cannabinoid biosynthesis and the feminisation process, converted to practical ways to manipulate these important agronomic traits. This will derisk the industrial hemp industry, encouraging increased cultivation of a nutritionally and economically valuable crop in Australia and create valuable intellectual property applicable globally.Read moreRead less