Novel Mechanism Underlying The Behavioural And Neurocognitive Deficits In Children With Sleep Disorders.
Funder
National Health and Medical Research Council
Funding Amount
$312,296.00
Summary
About one third of Australian children have a sleep disorder. Behavioural or academic problems are common in these children, however the link between sleep and daytime problems is still not clear. New research suggests the pattern of brain activity during deep sleep may provide some answers. This study will explore the link between brain activity during deep sleep and daytime functioning in children with sleep disorders, providing valuable information for treatment.
Novel Therapy For Enhancing Organ Maturation In Pre-term Babies
Funder
National Health and Medical Research Council
Funding Amount
$694,323.00
Summary
This project is developing a factor to enhance organ maturation and repair that may provide a new therapy for premature babies and fetuses with birth defects. This exciting new finding allows for the development of treatments of underdeveloped organs, in particular the lungs of premature and growth restricted babies. We are also trialing this factor in unborn babies with defects to the kidneys and lungs of which there is currently no cure.
Developmental Changes In Cerebral Oxygenation After Term And Preterm Birth
Funder
National Health and Medical Research Council
Funding Amount
$445,306.00
Summary
Approximately 10% of all births are preterm and the numbers of infants surviving are increasing. We have previously found that infants born preterm have lower blood pressure over the first 6 months after term equivalent age than infants born at term. We will use new technology to examine how preterm birth affects brain oxygenation and how this is altered with gestational age, sleep states and sleeping position, to provide insights into their increased risk for SIDS.
Improving Child Health Outcomes In Common, High Burden Conditions.
Funder
National Health and Medical Research Council
Funding Amount
$279,895.00
Summary
As medical advances over the past 50 years have helped to reduce traditional childhood illnesses such as infections, behavioural, developmental and mental health problems have increased. These problems affect at least 1 in 5 Australian children yet the vast majority of problems go undetected and untreated. I propose to develop, trial and disseminate evidence-based approaches to common child health problems including mental health and sleep problems.
Determining The Role Of Oxytocin And Associated Analogues In Treatments For Social Dysfunction
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
This proposal develops a research hub to study, understand and develop innovative treatments for social difficulties observed across mental health conditions. It identifies treatment targets to improve social difficulties, determines who is likely to respond to these targets, and shows how these benefits can be tracked in patients. To achieve these goals, this proposal places this laboratory at the centre of broad international and collaborative research, facilitating innovative training and pra ....This proposal develops a research hub to study, understand and develop innovative treatments for social difficulties observed across mental health conditions. It identifies treatment targets to improve social difficulties, determines who is likely to respond to these targets, and shows how these benefits can be tracked in patients. To achieve these goals, this proposal places this laboratory at the centre of broad international and collaborative research, facilitating innovative training and practice within Australian society.Read moreRead less
Tailoring A Brief Sleep Intervention For Autism: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$401,475.00
Summary
Up to 86% of children with Autism Spectrum Disorder (ASD) experience behavioural sleep problems which have been shown to be associated with increased core ASD symptoms, increased rates of internalizing and externalizing disorders, and increased parental stress. The “Sleeping Sound” study is a novel behavioural sleep intervention that has shown much promise as a treatment to reduce sleep problems and improve mental health outcomes in children with ASD.