Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of ....Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of the methodology to be developed is to expedite the discovery of new subclasses of diseases. Another is to provide prediction rules for the diagnosis and treatment of diseases.Read moreRead less
Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised impor ....Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised importance, this program will have direct implications in areas of condensed matter physics, quantum statistical mechanics, particle physics, complex systems, quantum information science and technology, quantum computation, engineered quantum systems and nanotechnology. Read moreRead less
Adapting the Bulk Synchronous Parallel processing model to Peer-to-Peer Networked Computing. Advances in distributed computing have shown that data parallel and parametric applications domains are amenable to wide area distribution. The project will advance the Bulk Synchronous Parallel processing model to describe innovative applications from the loosely synchronous domain, e.g. fluid dynamics, strategy algorithms and N-body problems are challenges that have significant scientific and industria ....Adapting the Bulk Synchronous Parallel processing model to Peer-to-Peer Networked Computing. Advances in distributed computing have shown that data parallel and parametric applications domains are amenable to wide area distribution. The project will advance the Bulk Synchronous Parallel processing model to describe innovative applications from the loosely synchronous domain, e.g. fluid dynamics, strategy algorithms and N-body problems are challenges that have significant scientific and industrial value. The project specializes the exciting peer-to-peer paradigm, a frontier of inter-networking technology. By using the latest techniques and taking advantage of the technology implosion caused by low cost parallel infrastructure, the project outcomes will give Australia a strong position in the future of parallel technology.Read moreRead less
Mathematical measurement and modelling of neuronal degeneration. Currently about 150,000 Australian's suffer from cognitive impairment due to Alzheimer's disease or dementia and this number is expected to double over the next few decades. By combining newly developed mathematical methods in complex systems with sophisticated neural imaging we will develop new techniques to advance the diagnosis and treatment of cognitive decline in normal ageing and neurodegenerative disease.
This project will ....Mathematical measurement and modelling of neuronal degeneration. Currently about 150,000 Australian's suffer from cognitive impairment due to Alzheimer's disease or dementia and this number is expected to double over the next few decades. By combining newly developed mathematical methods in complex systems with sophisticated neural imaging we will develop new techniques to advance the diagnosis and treatment of cognitive decline in normal ageing and neurodegenerative disease.
This project will also maintain the collaborative link between researchers in Biomathematics at Mount Sinai School of Medicine, New York and researchers in Applied Mathematics at UNSW that enables training of Australian scientists in the vital area of mathematical bio-complexity.Read moreRead less
Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast ....Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast cancer and contribute to the development of an automated diagnostic method, with the possibility of its application to other diseases. The project will also involve members of the regional community, train regional scientists and provide synchrotron experience for Australian scientists in time for Australia's first synchrotron.Read moreRead less
Implementing Feferman-Landin Logic. The objective of this project is to utilise computer based verification tools (such as PVS and Rewritting Logic) to develop a software engineering environment for specifying and verifying systems written in high-level programming languages such as Java, Scheme, and ML. The project will thus subtantially advance the use of formal computer based tools to develop reliable programs and specifications for life-critical systems. The project will also develop form ....Implementing Feferman-Landin Logic. The objective of this project is to utilise computer based verification tools (such as PVS and Rewritting Logic) to develop a software engineering environment for specifying and verifying systems written in high-level programming languages such as Java, Scheme, and ML. The project will thus subtantially advance the use of formal computer based tools to develop reliable programs and specifications for life-critical systems. The project will also develop formally
based interoperability between the PVS and Maude systems, two widely
used computer tools for reasoning about complex systems.Read moreRead less
Evolutionary multi-objective algorithms for Global Grids. This research investigates alternative software technologies for Grid-based evolutionary multi-objective decision algorithms. By employing the latest adaptive techniques and taking advantage of the low cost Grid infrastructure, new parallel evolutionary systems will be developed that can rapidly supply robust solutions to complex problems. This project will further develop an understanding of scaling issues in parallel evolutionary syste ....Evolutionary multi-objective algorithms for Global Grids. This research investigates alternative software technologies for Grid-based evolutionary multi-objective decision algorithms. By employing the latest adaptive techniques and taking advantage of the low cost Grid infrastructure, new parallel evolutionary systems will be developed that can rapidly supply robust solutions to complex problems. This project will further develop an understanding of scaling issues in parallel evolutionary systems and pave the way for even more widespread application of evolutionary techniques for large scale, data-intensive applications in science and industry.Read moreRead less
Non-commutative Fractal Geometry: New Invariants. This project capitilises on Australian strengths in mathematics, particularly non-commutative and fractal geometry. It will maintain and extend Australia's prominence in these subjects, providing excellent training and opportunities for young researchers. Given the wide range of applications of fractals, there is potential for future technological spin offs for Australia.
Novel approaches to strongly correlated quantum systems in two dimensions. The expected outcome of the research program is a significant boost in our understanding of strongly correlated quantum systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By strengthening both the underpinning theory and innovative computational tools to study quantum many-body systems, and by applying them to specific problems ....Novel approaches to strongly correlated quantum systems in two dimensions. The expected outcome of the research program is a significant boost in our understanding of strongly correlated quantum systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By strengthening both the underpinning theory and innovative computational tools to study quantum many-body systems, and by applying them to specific problems of recognized importance, this program will have direct implications in condensed matter physics and will exert significant influence in areas such as quantum chemistry, high energy physics, quantum computing, quantum atom optics and nanotechnology.Read moreRead less
Entanglement renormalization: a new route to strongly correlated fermions and novel states of matter in two dimensions. The expected outcome of the research program is a significant boost in our understanding of strongly correlated fermion systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By strengthening both the underpinning theory and innovative computational tools to study fermion systems, and by ....Entanglement renormalization: a new route to strongly correlated fermions and novel states of matter in two dimensions. The expected outcome of the research program is a significant boost in our understanding of strongly correlated fermion systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By strengthening both the underpinning theory and innovative computational tools to study fermion systems, and by applying them to specific problems of recognized importance, this program will have direct implications in condensed matter physics and will exert significant influence in areas such as quantum chemistry, particle, nuclear and atomic physics, quantum computing, quantum atom optics and nanotechnology.Read moreRead less