Cracking the code of snails to elucidate parasite disease transmission. In Australia, a disease caused by liver flukes causes major economic losses to livestock production. The role of Australian pond snails as intermediate hosts for this parasite is poorly understood. This project aims to explore the phylogeography, biology and genomics of these snails. It expects to create novel molecular resources for important snail species and verify their roles as key vectors of flatworm parasites. The cur ....Cracking the code of snails to elucidate parasite disease transmission. In Australia, a disease caused by liver flukes causes major economic losses to livestock production. The role of Australian pond snails as intermediate hosts for this parasite is poorly understood. This project aims to explore the phylogeography, biology and genomics of these snails. It expects to create novel molecular resources for important snail species and verify their roles as key vectors of flatworm parasites. The curation of genomic and transcriptomic data sets, and elucidation of snail–parasite interactions will underpin the development of environmental diagnostic tests and deliver a new generation of intervention strategies to reduce the burden of liver fluke disease through the control of their snail intermediate hosts.Read moreRead less
Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinicia ....Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinician to reduce fetal deaths and enhance the chances of good outcomes with resultant savings in social and financial costs to the community. The development of such equipment would spawn future research into intervention treatments and contribute to Australia's position as a world leader in computerised health monitoring systems.Read moreRead less
Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This inform ....Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This information will provide the basis for tailoring treatment to a patients needs. It is anticipated that marketing of the PD GeneChip within Australia and overseas may produce revenue of at least $40 million annually.Read moreRead less
Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to ....Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to influence land use decisions. This should provide significant benefits to landholders, governments involved in land management and the public through increased productivity, profitability, biodiversity and ecosystem health in the context of future climate, agricultural commodity and carbon market uncertainties.Read moreRead less
Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability hav ....Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability having choice and control in their living arrangements.Read moreRead less
Disaster risk reduction practices that leave nobody behind. This project aims to answer critical questions about how to assist people with disabilities (PWD) in disasters, what their support needs are and how they might help themselves to better prepare for disasters. Significance includes coupling a person-centred emergency preparedness tool with cross-sectoral processes to collect and use data about the support needs of PWD in emergencies, increase cross-sector communication and collaboration ....Disaster risk reduction practices that leave nobody behind. This project aims to answer critical questions about how to assist people with disabilities (PWD) in disasters, what their support needs are and how they might help themselves to better prepare for disasters. Significance includes coupling a person-centred emergency preparedness tool with cross-sectoral processes to collect and use data about the support needs of PWD in emergencies, increase cross-sector communication and collaboration between emergency managers and community services, and improve equitable access for PWD to community-level disaster risk reduction (DRR). The expected outcome will be the co-design of effective mechanisms that state & federal decision makers can use to scale-up disability-inclusive DRR across Australia.Read moreRead less
Increasing organisational capacity of community residential units to facilitate ageing in place for people with intellectual disability. Unique challenges face the disability, aged care and health sectors because of the increased life expectancy of people with life-long intellectual disability (ID) and the likelihood of their premature ageing. Although this group is recognised by Federal and State governments as requiring specific and special service arrangements, little is known about adapting ....Increasing organisational capacity of community residential units to facilitate ageing in place for people with intellectual disability. Unique challenges face the disability, aged care and health sectors because of the increased life expectancy of people with life-long intellectual disability (ID) and the likelihood of their premature ageing. Although this group is recognised by Federal and State governments as requiring specific and special service arrangements, little is known about adapting disability and aged care services to their needs. This research will inform the development of policy and programs in the disability, aged care, and health sectors. The research aims to improve the capacity of disability group homes to respond to the health and ageing issues of older people with ID,to improve their quality of life.Read moreRead less
DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers ....DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers. This is possible because undiscovered low copy number biomarkers (faint stars) exist in human diagnostic fluids at levels far lower than current proteomic array detection limits.Read moreRead less
Special Research Initiatives - Grant ID: SR0354583
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional s ....Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional surfaces for applications in biodevices. The program we envisage will break down the barriers imposed by disciplinary boundaries and technical terminology to bring together the skills and infrastructure required to make rapid advances in this field.Read moreRead less
The effect of acquiring a disability in adulthood. This project aims to analyse the effect the acquisition of a disability in adulthood has on subsequent socio-economic circumstances (employment, housing, education, income, social capital, wealth) and wellbeing. Researchers from epidemiology, econometrics and statistics will use longitudinal data to model the patterns of disability and subsequent socio-economic and health circumstances over time. The methods aim to make causal statements and pro ....The effect of acquiring a disability in adulthood. This project aims to analyse the effect the acquisition of a disability in adulthood has on subsequent socio-economic circumstances (employment, housing, education, income, social capital, wealth) and wellbeing. Researchers from epidemiology, econometrics and statistics will use longitudinal data to model the patterns of disability and subsequent socio-economic and health circumstances over time. The methods aim to make causal statements and provide a template for research and evaluation in this field. Outcomes are expected to set priorities for action to improve socio-economic conditions, productivity and health for people with disabilities.Read moreRead less