Neuronal Substrate Of Choice In The Rat Whisker System
Funder
National Health and Medical Research Council
Funding Amount
$405,851.00
Summary
Humans and other animals can optimise their goal-directed behaviour by linking stimuli or actions to consequent positive and negative rewards. How does an animal generate such associations, and make decisions in the natural environment where the associations are often uncertain, at times contradictory, and continuously changing? This project uses rat whisker system as an animal model to identify the neuronal basis of perceptual decision making and the role of context.
Fundamental flaws in the design and reporting of research outcomes can undermine evidence-based medicine, impede patient-centred care, cause harm to patients, and result in a waste of research dollars. Our 3-year multinational project engages with patients, caregivers, clinicians, researchers and policy makers, to establish core outcomes in haemodialysis. This will ensure that patient-centred outcomes are consistently measured and reported in haemodialysis trials and other forms of research.
The Australian Peritoneal Dialysis Outcomes And Practice Patterns Study (PDOPPS)
Funder
National Health and Medical Research Council
Funding Amount
$489,749.00
Summary
Peritoneal dialysis (PD) is a form of home dialysis that is both substantially cheaper and associated with better early survival than standard hospital-based haemodialysis. Its use in Australia has been severely limited by poor outcomes compared to the rest of the world. This international study aims to identify “real world” PD centre practices that will lead to better outcomes for Australian patients, greater uptake of home dialysis and health savings of tens of millions of dollars annually.
Evaluation Of The Efficacy And Safety Of Health Service Dialysate Sodium Practice On Clinical Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$1,958,205.00
Summary
Concerns the delivery of haemodialysis may be contributing to sodium retention and poor outcomes has led many health services to modify practice. However this modification is occurring in an unmeasured and haphazard manner leaving the impact unknown. This simple, pragmatic research will generate definitive evidence on the effect of health service dialysate sodium practices on the key clinical outcomes of death and cardiovascular events as well as health service utilisation.
Resilient Democracy for the 21st Century. This project will establish novel foundational theoretical frameworks for the design of democratic institutions that can withstand internal and external pressure towards autocratisation. It will develop state of the art dynamic models of information manipulation and political dynamics, and analyse large-scale online survey experiments, as well as contemporary and historical data. This combination will deliver new insights into the management of sensitive ....Resilient Democracy for the 21st Century. This project will establish novel foundational theoretical frameworks for the design of democratic institutions that can withstand internal and external pressure towards autocratisation. It will develop state of the art dynamic models of information manipulation and political dynamics, and analyse large-scale online survey experiments, as well as contemporary and historical data. This combination will deliver new insights into the management of sensitive information and how to protect democracy from information manipulation. Ultimately, the project will generate a body of theoretical and empirical evidence for the design of more effective and resilient democratic institutions for a more inclusive economic development. Read moreRead less
The economics of cooperative behaviour. Free-riding and rent-seeking, such as tax avoidance and nepotism, are group-undermining activities that societies including Australia continuously struggle with. The aim of this project is to develop a fuller understanding of how to protect human groups from these socially damaging group-related behaviours. Drawing on a conceptual grounding that combines ideas from across social science, the project aims to implement a suite of economic experiments to deve ....The economics of cooperative behaviour. Free-riding and rent-seeking, such as tax avoidance and nepotism, are group-undermining activities that societies including Australia continuously struggle with. The aim of this project is to develop a fuller understanding of how to protect human groups from these socially damaging group-related behaviours. Drawing on a conceptual grounding that combines ideas from across social science, the project aims to implement a suite of economic experiments to develop a view of humans' cooperative behaviour that unites several strands of economics literature and offers new insights about how institutions that counter free-riding and rent-seeking arise and are maintained.Read moreRead less