On-demand 3D polymer scaffolds for directed stem cell differentiation. The project will develop new polymer gels that can be sculpted into shapes, representing tissues and organs. This 3D scaffold will provide a surface with biological signals to create functional tissues from stem cells. The approach will create engineered intestinal tissue with great promise to increase the survival rates of colon cancer patients.
Clean technologies for the synthesis and purification of a biohybrid and biodegradable polymer. The project aims to transform an Australian industry in the forefront of the global market for manufacturing biodegradable polymers and boost export earnings derived from CO2 based biohybrid polymers. The project will develop cost-effective and clean methods for processing CO2 based polymers and demonstrate its potential for packaging and biomedical applications.
Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour ....Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour requirement, higher production rate and better quality control than conventional production methods. The new process will combine benefits from both supercritical fluid technology (green process) and microfluidics (high mass & heat transfer).Read moreRead less
Improving performance of solvent extraction equipment for the minerals processing industry. This project will develop a fundamental understanding of how a new type of solvent extraction column, which was recently introduced to the mining industry, responds to changes in process conditions and operating parameters. This will enable the potential for optimal and efficient use of these assets and ensure a competitive advantage for Australia's biggest export earner.
The elutriation of ultrafine particles according to their density. This study is concerned with exploiting a new and powerful mechanism for separating particles according to their density, with strong potential for recovering and concentrating tens of billions of dollars worth of valuable minerals annually. By coupling the new separation mechanism with a centrifugal force it should be possible to apply gravity separation technology, arguably for the first time, to the recovery of ultrafine parti ....The elutriation of ultrafine particles according to their density. This study is concerned with exploiting a new and powerful mechanism for separating particles according to their density, with strong potential for recovering and concentrating tens of billions of dollars worth of valuable minerals annually. By coupling the new separation mechanism with a centrifugal force it should be possible to apply gravity separation technology, arguably for the first time, to the recovery of ultrafine particles from 200 microns to well below 10 microns, at high separation efficiency, and high feed rates. This study is also ideal for training new researchers, especially at the PhD level, in an area of importance to Australia's economic future. Read moreRead less
Carbon-Supported Iron Catalysts for Selective Catalytic Reduction of NO. Nitric oxide (NO) is a major pollutant from combustion systems. This project aims to develop cost-effective and environmentally benign zerovalent iron catalysts supported on carbon material for selective catalytic reduction (SCR) of NO using CO and unburned hydrocarbons as in-situ reductants. By applying differential reactor experimentation, kinetic modelling and advanced material characterisation techniques, the research w ....Carbon-Supported Iron Catalysts for Selective Catalytic Reduction of NO. Nitric oxide (NO) is a major pollutant from combustion systems. This project aims to develop cost-effective and environmentally benign zerovalent iron catalysts supported on carbon material for selective catalytic reduction (SCR) of NO using CO and unburned hydrocarbons as in-situ reductants. By applying differential reactor experimentation, kinetic modelling and advanced material characterisation techniques, the research will unravel complex relationships among catalyst structural features and activity, NO reduction mechanisms, and catalyst performance under practically relevant combustion conditions that underpin the development of an effective yet affordable SCR technology to control NO emission from industrial utilities and automobiles.Read moreRead less
Nano-engineered catalysts for sustainable fuel production from waste . This project aims to address two major problems simultaneously-reducing the burden of non-recyclable waste currently going to landfill in Australia, and offsetting Australia’s reliance on imported diesel to support industry and transport needs. While approximately 95% of diesel consumed in Australia is imported, vast quantities of carbon-based waste ends up in landfill. Municipal Solid Waste (MSW) is a mixture of plant-based ....Nano-engineered catalysts for sustainable fuel production from waste . This project aims to address two major problems simultaneously-reducing the burden of non-recyclable waste currently going to landfill in Australia, and offsetting Australia’s reliance on imported diesel to support industry and transport needs. While approximately 95% of diesel consumed in Australia is imported, vast quantities of carbon-based waste ends up in landfill. Municipal Solid Waste (MSW) is a mixture of plant-based waste (including food, garden, paper, and wood) and fossil-fuel derived materials (plastics). Using an innovative and environmentally-sustainable catalytic process, the outcomes of this project are aimed alleviating Australia’s dependence on diesel fuel imports and better waste management solutions in Australia.Read moreRead less
Engineering of cartilage-based biomaterials under dynamic culture conditions. This work contributes to the development of advanced technologies in the area of biomaterials. The cartilage biomaterials generated in this work will lead to new medical applications in tissue reconstruction and replacement, which is of direct benefit to society by improving the methods used to treat joint disease and injury. As there is a significant commercial market for tissue-engineered cartilage products, this res ....Engineering of cartilage-based biomaterials under dynamic culture conditions. This work contributes to the development of advanced technologies in the area of biomaterials. The cartilage biomaterials generated in this work will lead to new medical applications in tissue reconstruction and replacement, which is of direct benefit to society by improving the methods used to treat joint disease and injury. As there is a significant commercial market for tissue-engineered cartilage products, this research also has implications for enhancing the scope and profitability of the Australian biotechnology industry. The project will be a vehicle for research training in a broad range of interdisciplinary areas. Students involved in the work will be equipped with a versatile and valuable combination of skills.Read moreRead less
Low-temperature plasma-catalytic conversion of CH4 and CO2 to alcohols. This project aims to investigate a novel concept of integrated low-temperature plasma and catalytic membrane hybrid reactor system for alcohols production from methane (CH4), carbon dioxide (CO2) and water vapour. This research will combine plasma physics and reaction engineering techniques to develop an innovative gas to liquid technology. The outcomes have the potential to transform the nation's natural gas industry, impro ....Low-temperature plasma-catalytic conversion of CH4 and CO2 to alcohols. This project aims to investigate a novel concept of integrated low-temperature plasma and catalytic membrane hybrid reactor system for alcohols production from methane (CH4), carbon dioxide (CO2) and water vapour. This research will combine plasma physics and reaction engineering techniques to develop an innovative gas to liquid technology. The outcomes have the potential to transform the nation's natural gas industry, improve energy efficiency, and utilise CO2 rich gas resources.Read moreRead less
Particle classification using a ferrofluid in a non uniform magnetic field. The separation of micron size components of suspensions according to the size and density of the particles is presently an intractable problem. However, by using a magnetized ferrofluid it should be possible to generate unique particle trajectories for each combination of particle size and density. This study investigates the potential of this strategy for separating such particles, laying the foundation for new small-sc ....Particle classification using a ferrofluid in a non uniform magnetic field. The separation of micron size components of suspensions according to the size and density of the particles is presently an intractable problem. However, by using a magnetized ferrofluid it should be possible to generate unique particle trajectories for each combination of particle size and density. This study investigates the potential of this strategy for separating such particles, laying the foundation for new small-scale diagnostic "lab-on a chip" technology that could be used in biotechnology to study whole blood, or in mineral processing to control energy intensive ball mills for mineral particle liberation.Read moreRead less