Transforming industrial waste into valuable carbons for iron-carbon alloys: Fundamental investigations of structure, impurity reactions and carbon dissolution. This project will deliver the comprehensive science that will enable the ferrous alloy industry to utilize industrial waste as a carbon resource. Novel recycling process will enhance the international competitiveness and environmental sustainability of Australian industries. At the same time, our advances will allow ferrous alloy producer ....Transforming industrial waste into valuable carbons for iron-carbon alloys: Fundamental investigations of structure, impurity reactions and carbon dissolution. This project will deliver the comprehensive science that will enable the ferrous alloy industry to utilize industrial waste as a carbon resource. Novel recycling process will enhance the international competitiveness and environmental sustainability of Australian industries. At the same time, our advances will allow ferrous alloy producers to consume substantial amounts of chemically inert, difficult to recycle industrial/composite waste, and significantly reduce the amount of waste being sent to landfills/illegal dumps. The technology will have a significant impact on the environment through reductions in greenhouse gas emissions, savings on raw materials and enhanced waste recycling. Read moreRead less
Unlocking Australia's offshore gas endowment. This project aims to develop practical new methods of predicting and detecting the formation of solids in gas and liquefied natural gas (LNG) production. Australia has large offshore reserves of natural gas and has made the investments necessary to help fuel the global transition to cleaner, reliable energy sources. However, conventional engineering approaches of producing gas from deep-water reserves have reached the limits of viability because of t ....Unlocking Australia's offshore gas endowment. This project aims to develop practical new methods of predicting and detecting the formation of solids in gas and liquefied natural gas (LNG) production. Australia has large offshore reserves of natural gas and has made the investments necessary to help fuel the global transition to cleaner, reliable energy sources. However, conventional engineering approaches of producing gas from deep-water reserves have reached the limits of viability because of the costs required to prevent solids forming in subsea pipelines or cryogenic LNG plants. The project’s expected outcome include sophisticated tools in open-access software based on these new predictive methods, and a step-change in Australia’s ability to access its offshore gas.Read moreRead less
Controllable synthesis of multifunctional boron-based 2D materials. This project aims to make it possible to control the synthesis of boron-based two-dimensional (2D) materials with the desired following features in single or multiple aspects: thickness, composition, lateral sizes, porosity, surface area, and functionality. It intends to do so by designing and synthesising novel precursors, and by optimising the fabrication process of boron-based 2D nanosheets for different applications. The pro ....Controllable synthesis of multifunctional boron-based 2D materials. This project aims to make it possible to control the synthesis of boron-based two-dimensional (2D) materials with the desired following features in single or multiple aspects: thickness, composition, lateral sizes, porosity, surface area, and functionality. It intends to do so by designing and synthesising novel precursors, and by optimising the fabrication process of boron-based 2D nanosheets for different applications. The project will advance our fundamental knowledge in synthetic chemistry, materials chemistry, materials engineering and physics. It is expected to take us closer to unlocking the potential of boron-based 2D materials for real-world applications in, for example, energy storage and high-performance flexible electronics.Read moreRead less
Fundamentals and practical applications of hierarchically-structured bulk materials. Structured bulk materials are very promosing for process intensification. By using structured bulk materials instead of fine particles, this project will have the opportunity to realise hydrogen or methane storage at very low pressure, and significantly speed up the production of alternative transport fuels from syn gas.
Structural studies of host-pathogen interactions. The host-pathogen interface represents a major frontier for biomedical and biotechnological applications. This project aims to understand at the atomic level two such interfaces. In the first instance, the project will elucidate the molecular basis for inhibition of premature host cell death by poxviruses, in particular vaccinia and variola virus, the causative agent of smallpox. In the second instance, the aim is to understand how defensins, a ....Structural studies of host-pathogen interactions. The host-pathogen interface represents a major frontier for biomedical and biotechnological applications. This project aims to understand at the atomic level two such interfaces. In the first instance, the project will elucidate the molecular basis for inhibition of premature host cell death by poxviruses, in particular vaccinia and variola virus, the causative agent of smallpox. In the second instance, the aim is to understand how defensins, a major class of host defence molecules, recognise microbial targets such as fungi, and exert a potent antimicrobial effect. Understanding the precise molecular mechanisms operating at both these host-pathogen interfaces this will provide novel avenues for the design of antiviral and antimicrobial agents.Read moreRead less
The ins and outs of HIV biology. This project aims to delineate the fundamental mechanisms that regulate the production of HIV and the ability of HIV to cause AIDS in infected patients. It will utilise state-of-the-art technologies to unearth new clues that govern the biology of HIV, with the ultimate goal to develop novel vaccine and treatment strategies against HIV.
Hierarchically structured carbon nanotube catalysts for the conversion of biomass to fuels and chemicals. Australia has significant biomass resources, which can be used to produce industrial chemicals and transport fuels. This project will develop a new family of carbon-nanotube-supported catalysts that will lead to improvements in process efficiency and performance for biofuels production.
Computational enzymology: exploring the free energy landscape of enzymatic catalysis. Most biochemical reactions depend on enzyme catalysis and understanding how enzymes work at the molecular level remains a central question. This project will develop a suite of computational models to study the mechanisms of enzyme-catalysed reactions and such knowledge holds promise for technological benefits in the form of new drugs and novel catalysts.
Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and bi ....Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and biomedical research. The sensor network discipline also stand to benefit from the understanding of multi-object system and control framework. Read moreRead less
Structural analysis of poxviruses: advancing our understanding of complex DNA viruses and their in vivo crystals. This project will use innovative structural biology approaches to investigate two key particles of poxviruses, the largest viruses infecting humans. Advance in understanding of immature particles and natural crystals of poxviruses will provide the basis for the development of broad-spectrum antivirals and novel microparticles for vaccine-delivery.