Use Of Expression Profiling To Identify Genes Influencing Cardiovascular Risk In The Norfolk Island Population Isolate
Funder
National Health and Medical Research Council
Funding Amount
$697,409.00
Summary
This study will use a unique population isolate from Norfolk Island. We aim to identify genes that play a role in cardiovascular disease risk. Norfolk has a population of ~1200 permanent residents, most of whom are direct descendents of 18th century English Bounty mutineers and Polynesian women. We will undertake gene expression mapping to identify genomic loci that influence cardiovascular disease using samples from this population isolate.
Structural Basis For Inhibition Of Malaria Invasion By Targeting The Apical Membrane Antigen Of Plasmodium Falciparum.
Funder
National Health and Medical Research Council
Funding Amount
$434,134.00
Summary
3 million children die every year from malaria infections. A leading vaccine candidate is a protein from the malaria parasite called AMA1. Humans that have been infected with malaria make antibodies to this protein which can kill parasites, however little is known about how this occurs. We aim to identify regions of the protein that generate antibodies that prevent malaria parasites from invading human cells and help in the search for a vaccine against malaria.
Building Decision Support Systems To Combat Emerging Infectious Diseases And Neglected Tropical Diseases: A Precision Public Health Approach
Funder
National Health and Medical Research Council
Funding Amount
$1,562,250.00
Summary
Emerging infectious diseases and neglected tropical diseases cause significant disease burden globally, and pose major health security threats in the Asia Pacific. The frequency and severity of disease outbreaks are increasing, mostly driven by environmental and socio-demographic change. My research program will use cutting-edge technologies and analytics to develop interactive, dynamic and user-friendly decision support systems that optimise surveillance and control of infectious diseases.
Improved design and control of brushless doubly-fed reluctance machine generators for wind power applications. The growing importance of the reduction in greenhouse gas emissions over the coming years is driving the increased usage of renewable energy sources such as wind power. Currently the cost of wind energy is considerably higher than fossil fuel energy sources. Part of the reason for this is the initial cost and ongoing maintenance of the wind turbines. The proposed research considers a n ....Improved design and control of brushless doubly-fed reluctance machine generators for wind power applications. The growing importance of the reduction in greenhouse gas emissions over the coming years is driving the increased usage of renewable energy sources such as wind power. Currently the cost of wind energy is considerably higher than fossil fuel energy sources. Part of the reason for this is the initial cost and ongoing maintenance of the wind turbines. The proposed research considers a new kind of generator based on the Brushless Doubly Fed Machine (BDFRM) that has the potential to lower the initial cost of the generator/inverter hardware of the wind turbine, and also decrease the ongoing maintenance costs. If the research is able to show that the BDFRM is able to realise its potential, then this will aid the further use of wind energy.Read moreRead less